Home Protein Tyrosine Kinase Ephrin receptor chemical NVP-BHG712 isomer

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NVP-BHG712 isomer Ephrin receptor chemical

Cat.No.E2835

NVP-BHG712 isomer, a regioisomer of NVP-BHG712, shows conserved non-bonded binding to EphA2 and EphB4.
NVP-BHG712 isomer Ephrin receptor chemical Chemical Structure

Chemical Structure

Molecular Weight: 503.48

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Quality Control

Batch: E283501 DMSO]100 mg/mL]false]Ethanol]2 mg/mL]false]Water]Insoluble]false Purity: 99.56%
99.56

Solubility

In vitro
Batch:

DMSO : 100 mg/mL (198.61 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 2 mg/mL

Water : Insoluble

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In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 503.48 Formula

C26H20F3N7O

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 2245892-85-5 -- Storage of Stock Solutions

Mechanism of Action

Targets/IC50/Ki
EphA2
EphB4
References

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