Calcium Channel Chemicals

Cat.No. Product Name Information Product Use Citations Product Validations
S7534 BAPTA-AM BAPTA-AM is a selective, membrane-permeable calcium chelator.
Nat Commun, 2025, 16(1):7699
JCI Insight, 2025, 10(16)e191245
Liver Int, 2025, 45(10):e70341
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S7074 Ionomycin Ionomycin (SQ23377) is a potent and selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. It induces the activation of protein kinase C (PKC) and promotes apoptosis.
Protein Cell, 2025, pwaf020
Nat Commun, 2025, 16(1):8054
Cancer Commun (Lond), 2025, 10.1002/cac2.70036
S2446 Levosimendan Levosimendan(OR1259,OR1855,Simsndan) is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure.
J Immunother Cancer, 2024, 12(11)e009805
Antiviral Res, 2017, 146:76-85
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S2397 Palmatine chloride Palmatine hydrochloride (Palmatine chloride (6CI,7CI); Fibrauretin) is a hydrochloride salt of palmatine which is a protoberberine alkaloid.
Molecules, 2021, 26(5)1210
J Med Virol, 2019, 91(8):1440-1447
S1911 Disodium Cromoglycate Disodium Cromoglycate (Gynazole ,FPL 670 (Cromolyn) Disodium,Cromolyn sodium) is an antiallergic drug with IC50 of 39 μg/mL.
E3642 Haliotidis concha Extract Haliotidis Concha Extract is extracted from the shell of Haliotidis Concha, which influences calcium channels, expression of PMCA1 mRNA, and regulates ion calcium channels and calcium-ATPase.
E2691 BAPTA tetrapotassium salt BAPTA tetrapotassium salt (BAPTA tetrapotassium) is a non-permeable, selective extracellular calcium chelator, with 105-fold greater affinity for Ca2+ than Mg2+, which is a valuable tool to study the role of calcium in cell signaling.
S5478 Dantrolene sodium Dantrolene sodium(F 440) acts as a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.
Vet Res, 2025, 56(1):199
ACS Omega, 2025, 7004-7012
ACS Omega, 2025, Article ASAP
S6994 TD-165 TD-165 is a PROTAC-based cereblon (CRBN) degrader. This compound comprises a cereblon (CRBN) ligand binding group, a linker and an von Hippel-Landau (VHL) binding group.