| S7534 |
BAPTA-AM
|
BAPTA-AM is a selective, membrane-permeable calcium chelator.
|
-
Nat Commun, 2025, 16(1):7699
-
JCI Insight, 2025, 10(16)e191245
-
Liver Int, 2025, 45(10):e70341
|
|
| S7074 |
Ionomycin
|
Ionomycin (SQ23377) is a potent and selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. It induces the activation of protein kinase C (PKC) and promotes apoptosis.
|
-
Protein Cell, 2025, pwaf020
-
Nat Commun, 2025, 16(1):8054
-
Cancer Commun (Lond), 2025, 10.1002/cac2.70036
|
|
| S2446 |
Levosimendan
|
Levosimendan(OR1259,OR1855,Simsndan) is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure.
|
-
J Immunother Cancer, 2024, 12(11)e009805
-
Antiviral Res, 2017, 146:76-85
|
|
| S2397 |
Palmatine chloride
|
Palmatine hydrochloride (Palmatine chloride (6CI,7CI); Fibrauretin) is a hydrochloride salt of palmatine which is a protoberberine alkaloid.
|
-
Molecules, 2021, 26(5)1210
-
J Med Virol, 2019, 91(8):1440-1447
|
|
| S1911 |
Disodium Cromoglycate
|
Disodium Cromoglycate (Gynazole ,FPL 670 (Cromolyn) Disodium,Cromolyn sodium) is an antiallergic drug with IC50 of 39 μg/mL.
|
|
|
| E3642 |
Haliotidis concha Extract
|
Haliotidis Concha Extract is extracted from the shell of Haliotidis Concha, which influences calcium channels, expression of PMCA1 mRNA, and regulates ion calcium channels and calcium-ATPase.
|
|
|
| E2691 |
BAPTA tetrapotassium salt
|
BAPTA tetrapotassium salt (BAPTA tetrapotassium) is a non-permeable, selective extracellular calcium chelator, with 105-fold greater affinity for Ca2+ than Mg2+, which is a valuable tool to study the role of calcium in cell signaling.
|
|
|
| S5478 |
Dantrolene sodium
|
Dantrolene sodium(F 440) acts as a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.
|
-
Vet Res, 2025, 56(1):199
-
ACS Omega, 2025, 7004-7012
-
ACS Omega, 2025, Article ASAP
|
|
| S6994 |
TD-165
|
TD-165 is a PROTAC-based cereblon (CRBN) degrader. This compound comprises a cereblon (CRBN) ligand binding group, a linker and an von Hippel-Landau (VHL) binding group.
|
|
|