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Calcium Channel Agonists

Cat.No. Product Name Information Product Use Citations Product Validations
S7924 Bay K 8644 Bay K 8644 is a racemate. Bay K 8644 is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.
J Neurotrauma, 2025, 10.1177/08977151251374286
EMBO Rep, 2024, 25(11):4777-4802
ACS Nano, 2021, 10.1021/acsnano.1c03517
Verified customer review of Bay K 8644
E4039 (S)-(-)-Bay K8644 (S)-(-)-Bay K8644 is a voltage-sensitive L-type calcium channel agonist. It also activates Ba2+ currents (Iba) with EC50 of 32 nM.
Nat Commun, 2025, 16(1):7115
Nature Communications, 2025, 7115
S5191 Cinacalcet Cinacalcet (AMG073, Sensipar, Cin) is an orally active, allosteric agonist of receptors for calcium (CaR) that increases the sensitivity of the CaR to Ca.
International Journal of Molecular Sciences, 2022, 4323
Int J Mol Sci, 2022, 23(8)4323
S9151 Praeruptorin E Praeruptorin E, isolated from Peucedanum praeruptorum Dunn., is a cardiotonic agent with selective cardiac calcium channel agonistic effect.
E0137 GV-58

GV-58 is a novel, selective N-type and P/Q-type Ca2+ channels agonist with IC50s of 7.21 μM and 8.81 μM, respectively.