Adenosine Deaminase

Inhibitory Selectivity

Adenosine Deaminase Products

All (3) Adenosine Deaminase Inhibitors (3)

Catalog No.	Information	Product Use Citations
S1199	Cladribine Cladribine (Leustatin, 2-CdA, 2-chlorodeoxyadenosine, 2-Chloro-2′-deoxyadenosine, CldAdo) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.	Nat Commun, 2021, 12(1):1275 Nat Commun, 2020, 29;11(1):2086 PLoS Pathog, 2020, 16;16(3):e1008341
S9521	Pentostatin Pentostatin is a potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.	Nat Metab, 2020, 10.1038/s42255-020-0227-4
S0950^New	Hibifolin Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in vitro.

Catalog No.

Information

Product Use Citations

Product Validations

S1199

Cladribine

Cladribine (Leustatin, 2-CdA, 2-chlorodeoxyadenosine, 2-Chloro-2′-deoxyadenosine, CldAdo) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.

Nat Commun, 2021, 12(1):1275

Nat Commun, 2020, 29;11(1):2086

PLoS Pathog, 2020, 16;16(3):e1008341

S9521

Pentostatin

Pentostatin is a potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.

Nat Metab, 2020, 10.1038/s42255-020-0227-4

S0950^New

Hibifolin

Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in vitro.

Catalog No.	Information	Product Use Citations
S1199	Cladribine Cladribine (Leustatin, 2-CdA, 2-chlorodeoxyadenosine, 2-Chloro-2′-deoxyadenosine, CldAdo) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.	Nat Commun, 2021, 12(1):1275 Nat Commun, 2020, 29;11(1):2086 PLoS Pathog, 2020, 16;16(3):e1008341
S9521	Pentostatin Pentostatin is a potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.	Nat Metab, 2020, 10.1038/s42255-020-0227-4
S0950^New	Hibifolin Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in vitro.

Catalog No.

Information

Product Use Citations

Product Validations

S1199