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Adenosine Deaminase

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Adenosine Deaminase Products

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Catalog No. Product Name Information Product Use Citations Product Validations
S0950 Hibifolin Hibifolin (Gossypetin-8-O-β-D-glucuronide) is a flavonol glycoside and acts as a potential inhibitor of adenosine deaminase (ADA) with a Ki of 49.92 μM. Hibifolin prevents β-amyloid-induced neurotoxicity in cultured cortical neurons.
S1199 Cladribine (RWJ 26251) Cladribine (RWJ 26251, Leustatin, 2-CdA, 2-chlorodeoxyadenosine, 2-Chloro-2′-deoxyadenosine, CldAdo, Jk 6251, NSC 105014) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.
Neoplasia, 2021, 23(12):1183-1191
Hum Cell, 2021, 10.1007/s13577-021-00639-4
Hum Cell, 2021, 10.1007/s13577-021-00579-z
S9521 Pentostatin Pentostatin is a potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Nat Metab, 2020, 10.1038/s42255-020-0227-4
S0950 Hibifolin Hibifolin (Gossypetin-8-O-β-D-glucuronide) is a flavonol glycoside and acts as a potential inhibitor of adenosine deaminase (ADA) with a Ki of 49.92 μM. Hibifolin prevents β-amyloid-induced neurotoxicity in cultured cortical neurons.
S1199 Cladribine (RWJ 26251) Cladribine (RWJ 26251, Leustatin, 2-CdA, 2-chlorodeoxyadenosine, 2-Chloro-2′-deoxyadenosine, CldAdo, Jk 6251, NSC 105014) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.
Neoplasia, 2021, 23(12):1183-1191
Hum Cell, 2021, 10.1007/s13577-021-00639-4
Hum Cell, 2021, 10.1007/s13577-021-00579-z
S9521 Pentostatin Pentostatin is a potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Nat Metab, 2020, 10.1038/s42255-020-0227-4