Home Microbiology Parasite inhibitor Nicarbazin For research use only.

Nicarbazin

Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug.

Nicarbazin Chemical Structure

Nicarbazin Chemical Structure

CAS: 330-95-0

Purity & Quality Control

Batch: S486601 DMSO] 9 mg/mL] false] Water] Insoluble] false] Ethanol] Insoluble] false Purity: 98%
98

Nicarbazin Related Products

Choose Selective Parasite Inhibitors

Biological Activity

Description Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug.
In vitro
In vitro Nicarbazin increases activity of lipoprotein lipase. It can act as a carrier ionophore, worsen oxidative stress and increase colony stimulating factors which may have affect on long term adverse reactions of drug[1].
In Vivo
In vivo Nicarbazin is an effective and wide spread recognized substance for controlling the protozoal diseases with low number of short term adverse reactions[1]. It can negatively affect reproduction by reducing egg production, egg weight, and egg hatchability[2].

Chemical Information & Solubility

Molecular Weight 426.38 Formula

C13H10N4O5.C6H8N2O
CAS No. 330-95-0 SDF --
Smiles CC1=CC(=NC(=O)N1)C.C1=CC(=CC=C1NC(=O)NC2=CC=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 9 mg/mL ( (21.1 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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