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Benzyl benzoate

Name: Benzyl benzoate
Brand: Selleck Chemicals
SKU: S4599
Rating: 5 (1 reviews)

Synonyms: Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester

Catalog No.S4599 Purity: 99.65%

Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.

Benzyl benzoate Chemical Structure

CAS: 120-51-4

Purity & Quality Control

Batch: S459901 Purity: 99.65%

99.65

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Biological Activity

Description	Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.

In vitro
In vitro	Benzyl benzoate possess oestrogenic activity in MCF7 human breast cancer cells in vitro. It is able to increase the growth of oestrogen-dependent MCF7 human breast cancer cells^[1].
Cell Research	Cell lines	Oestrogen-responsive MCF7 human breast cancer cell line
	Concentrations	0-100 μM
	Incubation Time	7 days
	Method	Cells are added to the required volume of phenol red-free RPMI 1640 medium containing 5% DCFCS at a concentration of about 0.2 × 10⁵ cells ml⁻¹ and plated in monolayer in 0.5 ml aliquots into 24-well plastic tissue culture dishes (Nunc). After 24 h, the medium is changed to the same medium but containing the required concentration of test compound. Culture medium is changed routinely every 3–4 days. Cell counts are performed by counting released nuclei on a model ZBI Coulter Counter.

References

[1] Charles AK, et al. J Appl Toxicol. 2009, 29(5):422-434.

Chemical Information & Solubility

Molecular Weight	212.24	Formula	C₁₄H₁₂O₂
CAS No.	120-51-4	SDF	Download Benzyl benzoate SDF
Density	1.118 g/mL at 20 °C
Smiles	C1=CC=C(C=C1)COC(=O)C2=CC=CC=C2
Storage (From the date of receipt)	2 year -80°C liquid	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	2 year -80°C liquid		1 month-20°Cin solvent

In vitro
Batch:

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In vivo
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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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