Disulfiram

Disulfiram is an agent used to support the treatment of chronic alcoholism by producing an acute sensitivity to alcohol.

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In DMSO USD 130 In stock
USD 97 In stock
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Disulfiram  Chemical Structure

Disulfiram Chemical Structure
Molecular Weight: 296.54

Validation & Quality Control

Customer Reviews(1)

Quality Control & MSDS

Related Compound Libraries

Disulfiram is available in the following compound libraries:

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Product Description

Biological Activity

Disulfiram is an agent used to support the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram is also being studied as a treatment for cocaine dependence, as it prevents the breakdown of dopamine (a neurotransmitter whose release is stimulated by cocaine); the excess dopamine results in increased anxiety, higher blood pressure, restlessness and other unpleasant symptoms. Several studies have reported that it has anti-protozoal activity as well. [1]

Chemical Information

Download Disulfiram SDF
Molecular Weight (MW) 296.54
Formula

C10H20N2S4

CAS No. 97-77-8
Storage 3 years -20℃Powder
6 months-80℃in DMSO
Syonnyms Antabuse, Antabus
Solubility (25°C) * In vitro DMSO 59 mg/mL (198 mM)
Water <1 mg/mL (<1 mM)
Ethanol 59 mg/mL (198 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name

Preparing Stock Solutions

Stock Solution (1ml DMSO) 1mM 10mM 20mM 30mM
Mass(mg) 0.29654 2.9654 5.9308 8.8962

Research Area

Customer Reviews (1)


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Rating
Source J Proteomics, 2013, 79:114-22. Disulfiram purchased from Selleck
Method Motility Assay
Cell Lines human sperm
Concentrations 10-80 uM
Incubation Time 0, 15, 30, 60 or 120 min
Results Disulfiram inhibited sperm motility.

Product Citations (1)

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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