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Kinesin spindle protein

Cat.No. Product Name Feedback Added
S2737

ARRY-520 

Dec 2011
ARRY-520 is a potent and selective kinesin spindle protein (KSP) inhibitor with an IC50 of 15 nM for A2780, CP70 and 01-28 cell lines in vitro.
S2731

AZ 3146 

Nov 2011
AZ 3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor with an IC50 of 35 nM.
S1452

Ispinesib (SB-715992)

Jul 2010
Ispinesib (SB 715992) is a potent mitotic kinesin KSP (Eg5) inhibitor with a Ki and an IC50 of 0.6 and 4.1 nM, respectively.
S2182

SB 743921

Jan 2011
SB743921 is a second generation, highly potent and active KSP inhibitor with a Ki of 0.1 nM for KSP (Eg5).
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