TACC3

Other Cytoskeletal Signaling Related Inhibitors

HSP Kinesin Microtubule Associated Integrin PAK Dynamin MLCK Gap-Junction Actin Cardiac Myosin

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S8965	BO-264	BO-264 is a potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3) with IC50 of 188 nM and Kd of 1.5 nM. This compound specifically blocks the function of FGFR3-TACC3 fusion protein. It induces SAC-dependent mitotic arrest, apoptosis and DNA damage with antitumor activities.
S5919	KHS101 hydrochloride	KHS101 is a small-molecule inhibitor of TACC3, which is a key component of centrosome-microtubule dynamic networks.