Gap-Junction

Other Cytoskeletal Signaling Related Inhibitors

HSP Kinesin Microtubule Associated Integrin PAK Dynamin MLCK TACC3 Actin Cardiac Myosin

Cat.No.	Product Name	Information
S0339	Gap 26	Gap 26, a connexin mimetic peptide that composeds of residue no. 63-75 of the extracellular loop 1 of connexin 43 (Cx43), is a gap junction inhibitor. This compound blocks photoliberating inositol-1,4,5-trisphosphate triggers ATP release.
E7978	Danegaptide	Danegaptide is a potent and orally active gap-junction modifier that improves cardiac conduction and reduces atrial fibrillation/flutter in the canine sterile pericarditis model by enhancing gap-junction communication.
S6946	Gap19	Gap19 is a nonapeptide derived from the cytoplasmic loop (CL) of Cx43 and acts as a selective connexin 43 (Cx43) hemichannel blocker. This compound blocks Cx43 hemichannels without inhibiting gap junctions (GJs) at IC50 of 6.5 μM when applied intracellulary.
E0040	Gap 27	Gap 27 is a synthetic connexin-mimetic peptide and acts as a gap junction inhibitor. This compound is highly effective in interrupting co-operative cell-cell interactions, such as the synchronous beating of embryonic cardiomyocytes.