IDO

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S7111 NLG919 <1 mg/mL 15 mg/mL 30 mg/mL
S7756 Indoximod (NLG-8189) <1 mg/mL 1 mg/mL <1 mg/mL
S7910 Epacadostat (INCB024360) <1 mg/mL 87 mg/mL 53 mg/mL
S7587 INCB024360 analogue <1 mg/mL 54 mg/mL 54 mg/mL
Catalog No. Information Product Use Citations Product Validations
S7111

NLG919

NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM in cell-free assays. Phase 1.

S7756

Indoximod (NLG-8189)

Indoximod (NLG-8189), a methylated tryptophan, acts as an IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor, and reverses IDO-mediated immune suppression. Phase 2.

S7910

Epacadostat (INCB024360)

Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO).

S7587

INCB024360 analogue

INCB024360 analogue is a potent, competitive IDO1 (indoleamine-(2,3)-dioxygenase) inhibitor with IC50 of 67 nM. Phase 2.