SREBP

SREBP Products

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  • SREBP Inhibitors (4)
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Catalog No. Product Name Information Product Use Citations Product Validations
S8284 Fatostatin HBr Fatostatin HBr is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.
Cell Rep, 2023, 42(8):112963
Respir Res, 2023, 24(1):8
Ann Transl Med, 2022, 10(18):958
S9785 Fatostatin

Fatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells.

bioRxiv, 2024, 10.1101/2024.01.16.575899
EMBO Rep, 2021, e52537
Front Oncol, 2021, 11:796152
S9067 Pseudoprotodioscin Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
E0209 Cinobufotalin

Cinobufotalin, extracted from the skin secretion of the giant toad, is a novel SREBP1 inhibitor that suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.

S8284 Fatostatin HBr Fatostatin HBr is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.
Cell Rep, 2023, 42(8):112963
Respir Res, 2023, 24(1):8
Ann Transl Med, 2022, 10(18):958
S9785 Fatostatin

Fatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells.

bioRxiv, 2024, 10.1101/2024.01.16.575899
EMBO Rep, 2021, e52537
Front Oncol, 2021, 11:796152
S9067 Pseudoprotodioscin Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
E0209 Cinobufotalin

Cinobufotalin, extracted from the skin secretion of the giant toad, is a novel SREBP1 inhibitor that suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.

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Tags: SREBP inhibitor|SREBP agonist|SREBP activator|SREBP inducer|SREBP antagonist|SREBP signaling pathway|SREBP assay kit