SREBP antagonist | SREBP inhibitor | SREBP agonist

Not only can you personalize your library with chemicals from within Selleck’s inventory, but we can also purchase chemicals from other companies and integrate them into your custom library. Build the right library for your research endeavors by choosing from compounds in all of our available libraries.

Please contact us at [email protected] to customize your library.

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Specific Compounds Quantities 96 or 384 well Plate Map Dry/solid or DMSO solution

Antibodies

InVivo Antibodies

Therapeutic Antibodies

Bioreagents

qPCR: 2x SYBR Green qPCR Master Mix; 2x SYBR Green qPCR Master Mix(Low ROX); 2x SYBR Green qPCR Master Mix(High ROX)

Protein Assay: Protein A/G Magnetic Beads for IP; Anti-Flag magnetic beads; Anti-Flag Affinity Gel; Anti-Myc magnetic beads; Anti-HA magnetic beads; Magnetic Separator; Poly FLAG Peptide lyophilized powder

Protease Inhibitor Cocktail: Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO); Phosphatase Inhibitor Cocktail (2 Tubes, 100X)

Cell Biology: Cell Counting Kit-8 (CCK-8)

Animal Experiment: Mouse Direct PCR Kit (For Genotyping)

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Catalog No.	Product Name	Information	Product Use Citations
S8284	Fatostatin (125B11) HBr	Fatostatin HBr (Fatostatin A, 125B11) is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.	EMBO Rep, 2021, e52537 Nat Metab, 2021, 10.1038/s42255-021-00479-4 Cell, 2020, S0092-8674(20)31626-3
S9067	Pseudoprotodioscin	Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
S9785	Fatostatin	Fatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells.	EMBO Rep, 2021, e52537 Reproduction, 2021, 162(6):397-410
S8284	Fatostatin (125B11) HBr	Fatostatin HBr (Fatostatin A, 125B11) is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.	EMBO Rep, 2021, e52537 Nat Metab, 2021, 10.1038/s42255-021-00479-4 Cell, 2020, S0092-8674(20)31626-3
S9067	Pseudoprotodioscin	Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
S9785	Fatostatin	Fatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells.	EMBO Rep, 2021, e52537 Reproduction, 2021, 162(6):397-410

SREBP

SREBP Products