SREBP

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SREBP Products

All (4)
SREBP Inhibitors (4)
New SREBP Products

Catalog No.	Product Name	Information	Product Use Citations
E0209^New	Cinobufotalin	Cinobufotalin, extracted from the skin secretion of the giant toad, is a novel SREBP1 inhibitor that suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.
S8284	Fatostatin (125B11) HBr	Fatostatin HBr (Fatostatin A, 125B11) is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.	EMBO Rep, 2021, e52537 Nat Metab, 2021, 10.1038/s42255-021-00479-4 Cell, 2020, S0092-8674(20)31626-3
S9067	Pseudoprotodioscin	Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
S9785	Fatostatin	Fatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells.	EMBO Rep, 2021, e52537 Front Oncol, 2021, 11:796152 Reproduction, 2021, 162(6):397-410
E0209^New	Cinobufotalin	Cinobufotalin, extracted from the skin secretion of the giant toad, is a novel SREBP1 inhibitor that suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.
S8284	Fatostatin (125B11) HBr	Fatostatin HBr (Fatostatin A, 125B11) is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.	EMBO Rep, 2021, e52537 Nat Metab, 2021, 10.1038/s42255-021-00479-4 Cell, 2020, S0092-8674(20)31626-3
S9067	Pseudoprotodioscin	Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
S9785	Fatostatin	Fatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells.	EMBO Rep, 2021, e52537 Front Oncol, 2021, 11:796152 Reproduction, 2021, 162(6):397-410
E0209^New	Cinobufotalin	Cinobufotalin, extracted from the skin secretion of the giant toad, is a novel SREBP1 inhibitor that suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.