SCD
Inhibitory Selectivity
SCD Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S1158 |
MK-8245MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Phase 2. |
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| S8076 |
PluriSIn #1 (NSC 14613)PluriSIn #1 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs. |
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| S9607New |
A939572A939572 is a potent and orally bioavailable stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 of <4 nM and 37 nM for mSCD1 and hSCD1, respectively. |
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| S5120 |
ElemicinElemicin (3,4,5-trimethoxyallylbenzene) is a constituent of the oleoresin and the essential oil of Canarium luzonicum. Elemicin is a constituent of natural aromatic phenylpropanoids present in many herbs and spices. Elemicin inhibits Stearoyl-CoA Desaturase 1(SCD1) activity in the liver by metabolic activation. |
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| S6842 |
MF-438MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with IC50 of 2.3 nM for rSCD1. |
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| S4470New |
CVT-11127CVT-11127 (FMK13918) is an inhibitor of stearoylCoA desaturase-1 (SCD1). CVT-11127 reduces lipid synthesis and impaires proliferation by blocking the progression of cell cycle through the G(1)/S boundary and by triggering programmed cell death. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S1158 |
MK-8245MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Phase 2. |
||
| S8076 |
PluriSIn #1 (NSC 14613)PluriSIn #1 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs. |
||
| S9607New |
A939572A939572 is a potent and orally bioavailable stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 of <4 nM and 37 nM for mSCD1 and hSCD1, respectively. |
||
| S5120 |
ElemicinElemicin (3,4,5-trimethoxyallylbenzene) is a constituent of the oleoresin and the essential oil of Canarium luzonicum. Elemicin is a constituent of natural aromatic phenylpropanoids present in many herbs and spices. Elemicin inhibits Stearoyl-CoA Desaturase 1(SCD1) activity in the liver by metabolic activation. |
||
| S6842 |
MF-438MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with IC50 of 2.3 nM for rSCD1. |
||
| S4470New |
CVT-11127CVT-11127 (FMK13918) is an inhibitor of stearoylCoA desaturase-1 (SCD1). CVT-11127 reduces lipid synthesis and impaires proliferation by blocking the progression of cell cycle through the G(1)/S boundary and by triggering programmed cell death. |
