Thalidomide-OH

For research use only.

Catalog No.S1015 Synonyms: Cereblon ligand 2, E3 ligase Ligand 2

CAS No. 5054-59-1

Thalidomide-OH (Cereblon ligand 2, E3 ligase Ligand 2) is the Thalidomide-based Cereblon ligand that is applicable to the recruitment of CRBN protein. Thalidomide-OH can be connected to the ligand for protein by a linker to form PROTACs.

Purity & Quality Control

Biological Activity

Description Thalidomide-OH (Cereblon ligand 2, E3 ligase Ligand 2) is the Thalidomide-based Cereblon ligand that is applicable to the recruitment of CRBN protein. Thalidomide-OH can be connected to the ligand for protein by a linker to form PROTACs.

Protocol

References

Solubility (25°C)

Chemical Information

Molecular Weight
Formula
CAS No. 5054-59-1
Storage powder
in solvent
Synonyms Cereblon ligand 2, E3 ligase Ligand 2
Smiles C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)O

In vivo Formulation Calculator (Clear solution)

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID