SUMO

Isoform-selective Products

SUMO Products

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  • SUMO Inhibitors (6)
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Catalog No. Product Name Information Product Use Citations Product Validations
S8696 2-D08 2-D08 (2',3',4'-trihydroxy flavone) is a cell permeable, mechanistically unique inhibitor of protein sumoylation.
Acta Pharmaceutica Sinica B, 2024, 10.1016/j.apsb.2024.01.006
J Biol Chem, 2023, 299(10):105215
J Biol Chem, 2023, 299(10):105215
S8829 Subasumstat (TAK-981) Subasumstat (TAK-981) is a novel, selective inhibitor of the SUMOylation enzymatic cascade with potential immune-activating and antineoplastic activities.
Nat Struct Mol Biol, 2023, 10.1038/s41594-023-01045-0
Cell Death Dis, 2023, 14(2):170
Sci Adv, 2023, 9(4):eadd4969
S9432 Ginkgolic Acid Ginkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT).
CNS Neurosci Ther, 2022, 10.1111/cns.13871
Neurochem Res, 2021, 10.1007/s11064-021-03260-x
S9159 momordin-Ic Momordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo.
Int J Mol Sci, 2022, 23(15)8282
S4922 NSC 632839 NSC 632839 is not only a DUB inhibitor, but also a deSUMOylase inhibitor, it inhibits USP2, USP7, and SENP2 with EC50 of 45 μM, 37 μM, and 9.8 μM, respectively.
S9445 Ginkgolic Acid (C13:0) Ginkgolic Acid (C13:0) is a natural anticariogenic agent in Ginkgo biloba L. that exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. Ginkgolic acid is a potent sumoylation inhibitor and reported to inhibit histone acetylation transferase (HAT).
S8696 2-D08 2-D08 (2',3',4'-trihydroxy flavone) is a cell permeable, mechanistically unique inhibitor of protein sumoylation.
Acta Pharmaceutica Sinica B, 2024, 10.1016/j.apsb.2024.01.006
J Biol Chem, 2023, 299(10):105215
J Biol Chem, 2023, 299(10):105215
S8829 Subasumstat (TAK-981) Subasumstat (TAK-981) is a novel, selective inhibitor of the SUMOylation enzymatic cascade with potential immune-activating and antineoplastic activities.
Nat Struct Mol Biol, 2023, 10.1038/s41594-023-01045-0
Cell Death Dis, 2023, 14(2):170
Sci Adv, 2023, 9(4):eadd4969
S9432 Ginkgolic Acid Ginkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT).
CNS Neurosci Ther, 2022, 10.1111/cns.13871
Neurochem Res, 2021, 10.1007/s11064-021-03260-x
S9159 momordin-Ic Momordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo.
Int J Mol Sci, 2022, 23(15)8282
S4922 NSC 632839 NSC 632839 is not only a DUB inhibitor, but also a deSUMOylase inhibitor, it inhibits USP2, USP7, and SENP2 with EC50 of 45 μM, 37 μM, and 9.8 μM, respectively.
S9445 Ginkgolic Acid (C13:0) Ginkgolic Acid (C13:0) is a natural anticariogenic agent in Ginkgo biloba L. that exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. Ginkgolic acid is a potent sumoylation inhibitor and reported to inhibit histone acetylation transferase (HAT).

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Tags: SUMO Inhibition | SUMO antibody | SUMO inhibitors | SUMO modulation