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SUMO Products

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Catalog No. Product Name Information Product Use Citations Product Validations
S4922 NSC 632839 NSC 632839 is not only a DUB inhibitor, but also a deSUMOylase inhibitor, it inhibits USP2, USP7, and SENP2 with EC50 of 45 μM, 37 μM, and 9.8 μM, respectively.
S8696 2-D08 2-D08 (2',3',4'-trihydroxy flavone) is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET (c-RET), KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays.
Nat Commun, 2021, 12(1):4794
Cancers (Basel), 2021, 13(14)3475
Cancer Sci, 2021, 112(10):4075-4086
S8829 Subasumstat (TAK-981) Subasumstat (TAK-981) is a novel, selective inhibitor of the SUMOylation enzymatic cascade with potential immune-activating and antineoplastic activities.
Mol Cell Biol, 2021, 10.1128/MCB.00135-21
Research Square, 2021, 10.21203/rs.3.rs-620216/v1
S9159 momordin-Ic Momordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo.
S9432 Ginkgolic Acid Ginkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT).
Neurochem Res, 2021, 10.1007/s11064-021-03260-x
S9445 Ginkgolic Acid (C13:0) Ginkgolic Acid (C13:0) is a natural anticariogenic agent in Ginkgo biloba L. that exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. Ginkgolic acid is a potent sumoylation inhibitor and reported to inhibit histone acetylation transferase (HAT).
A5175 SUMO1 Rabbit Recombinant mAb SUMO1 Rabbit Recombinant mAb detects endogenous level of total SUMO1.
A5196 SUMO4 Rabbit Recombinant mAb SUMO4 Rabbit Recombinant mAb detects endogenous level of total SUMO4.
A5199 Sumo2/3 Rabbit Recombinant mAb Sumo2/3 Rabbit Recombinant mAb detects endogenous level of total Sumo2/3.
S4922 NSC 632839 NSC 632839 is not only a DUB inhibitor, but also a deSUMOylase inhibitor, it inhibits USP2, USP7, and SENP2 with EC50 of 45 μM, 37 μM, and 9.8 μM, respectively.
S8696 2-D08 2-D08 (2',3',4'-trihydroxy flavone) is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET (c-RET), KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays.
Nat Commun, 2021, 12(1):4794
Cancers (Basel), 2021, 13(14)3475
Cancer Sci, 2021, 112(10):4075-4086
S8829 Subasumstat (TAK-981) Subasumstat (TAK-981) is a novel, selective inhibitor of the SUMOylation enzymatic cascade with potential immune-activating and antineoplastic activities.
Mol Cell Biol, 2021, 10.1128/MCB.00135-21
Research Square, 2021, 10.21203/rs.3.rs-620216/v1
S9159 momordin-Ic Momordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo.
S9432 Ginkgolic Acid Ginkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT).
Neurochem Res, 2021, 10.1007/s11064-021-03260-x
S9445 Ginkgolic Acid (C13:0) Ginkgolic Acid (C13:0) is a natural anticariogenic agent in Ginkgo biloba L. that exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. Ginkgolic acid is a potent sumoylation inhibitor and reported to inhibit histone acetylation transferase (HAT).
A5175 SUMO1 Rabbit Recombinant mAb SUMO1 Rabbit Recombinant mAb detects endogenous level of total SUMO1.
A5196 SUMO4 Rabbit Recombinant mAb SUMO4 Rabbit Recombinant mAb detects endogenous level of total SUMO4.
A5199 Sumo2/3 Rabbit Recombinant mAb Sumo2/3 Rabbit Recombinant mAb detects endogenous level of total Sumo2/3.
Tags: SUMO Inhibition | SUMO antibody | SUMO inhibitors | SUMO modulation