Home Others Others Rhamnose

research use only

Rhamnose

Cat.No.E0245

Rhamnose(L-Rhamnose) is an important 6-deoxy sugar present in many natural products, glycoproteins, and structural polysaccharides.
Rhamnose Chemical Structure

Chemical Structure

Molecular Weight: 164.16

Jump to

Quality Control

Batch: E024501 DMSO]33 mg/mL]false]]]false]]]false Purity: 99.36%
99.36

Solubility

In vitro
Batch:

DMSO : 33 mg/mL (201.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Molarity Calculator

Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
+
%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 164.16 Formula

C6H12O5

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 3615-41-6 -- Storage of Stock Solutions

Synonyms L-Rhamnose Smiles CC(O)C(O)C(O)C(O)C=O

Mechanism of Action

In vitro

The polymeric copies of a rhamnose motif form glycopolymers (ARGPs), which can bind endogenous antirhamnose antibodies present in human serum, thus attract antibodies from human serum to the target cell surface.
In vivo

Rhamnose(Rha) conjugated immunogens induces high titers of anti-Rha antibodies in wildtype mice, which can replace α1,3galactosyltransferase knockout (α1,3GT KO) mice in such antigen/antibody-mediated vaccine design when developing cancer immunotherapies.
References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06392360 Recruiting
Metabolic Disturbance|Permeability; Increased
Appalachian State University|AGRANA
 May 13 2024 Not Applicable
NCT05999708 Withdrawn
Colitis Ulcerative
GlaxoSmithKline
 October 31 2023 Phase 1
NCT04109352 Unknown status
Glucose-Galactose Malabsorption|Enteropathy|Malnutrition Child|Intestinal Permeability|Linear Growth Failure
University of Virginia|International Atomic Energy Agency|Flinders University|International Centre for Diarrhoeal Disease Research Bangladesh|St. John''s Research Institute|The University of The West Indies|Mmust Masinde Muliro University of Science and Technology|Asociacion Benefica Prisma|Scottish Universities Environmental Research Centre|University of Michigan|Tropical Diseases Research Centre Zambia|Gastroenterology Services Ltd.
 September 1 2019 --
NCT03986476 Completed
IBS
Örebro University Sweden
 March 26 2019 Not Applicable

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.