Deoxycholic acid sodium salt

For research use only.

Catalog No.S3069 Synonyms: Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA

Deoxycholic acid sodium salt Chemical Structure

CAS No. 302-95-4

Deoxycholic acid sodium salt (Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA) is specifically responsible for activating the TGR5 receptor (GPCR19) that stimulates brown adipose tissue (BAT) thermogenic activity.

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Biological Activity

Description

Deoxycholic acid sodium salt (Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA) is specifically responsible for activating the TGR5 receptor (GPCR19) that stimulates brown adipose tissue (BAT) thermogenic activity.

Targets
GPCR19 [1]
()

Protocol

Solubility (25°C)

In vitro DMSO 83 mg/mL (200.21 mM)
Water 83 mg/mL (200.21 mM)
Ethanol ''''83 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 414.55
Formula

C24H39NaO4

CAS No. 302-95-4
Storage powder
in solvent
Synonyms Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01632917 Completed Drug: ATX-101 - U.S.|Drug: ATX-101 - EU Healthy Kythera Biopharmaceuticals June 2012 Phase 1
NCT01462786 Completed Drug: ATX-101 Healthy Kythera Biopharmaceuticals October 2011 Phase 1
NCT01319916 Completed Drug: ATX-101 Healthy Kythera Biopharmaceuticals December 2010 Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID