GPCR19

GPCR19 Products

  • All (7)
  • GPCR19 Activators (2)
  • GPCR19 Antagonist (1)
  • GPCR19 Agonists (4)
  • New GPCR19 Products
Catalog No. Product Name Information Product Use Citations Product Validations
S6806 SBI-115 SBI-115 is a novel TGR5 (GPCR19) antagonist. SBI-115 decreases cell proliferation, cholangiocyte spheroid growth and cAMP levels in cystic cholangiocytes.
Cells, 2023, 12(4)526
Nat Commun, 2022, 13(1):3419
Research Square, 2021, 10.21203/rs.3.rs-274411/v1
S4689 Deoxycholic acid Deoxycholic acid (Deoxycholate, Desoxycholic acid, Cholerebic, Cholorebic) is a cytolytic agent. The physiologic effect of deoxycholic acid is by means of decreased cell membrane integrity. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
Bio Protoc, 2022, 12(20)e4533
S0193 TGR5 Receptor Agonist TGR5 Receptor Agonist (TGR5, CCDC, MDK00245, compd 6) is a potent agonist of TGR5(GPCR19, GPBAR1, M-BAR). TGR5 Receptor Agonist shows improved potency with pEC50 of 6.8 and 7.5 in the U2-OS cell assay and in melanophore cells, respectively.
Research Square, 2021, 10.21203/rs.3.rs-274411/v1
S0034 BAR501 BAR501 is a potent and selective G protein-coupled bile acid receptor 1 (GPBAR1, GPCR19, TGR5) agonist that effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1 with EC50 of 1 μM.
S2311 Hyodeoxycholic acid (HDCA) Hyodeoxycholic (HDCA, NSC 60672) acid is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria.
S3069 Deoxycholic acid sodium salt

Deoxycholic acid sodium salt (Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA) is specifically responsible for activating the TGR5 receptor (GPCR19) that stimulates brown adipose tissue (BAT) thermogenic activity.

S6741 SB-756050 SB-756050 is a selective TGR5 agonist (EC50 = 1.3 μM for the human receptor).
S4689 Deoxycholic acid Deoxycholic acid (Deoxycholate, Desoxycholic acid, Cholerebic, Cholorebic) is a cytolytic agent. The physiologic effect of deoxycholic acid is by means of decreased cell membrane integrity. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
Bio Protoc, 2022, 12(20)e4533
S3069 Deoxycholic acid sodium salt

Deoxycholic acid sodium salt (Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA) is specifically responsible for activating the TGR5 receptor (GPCR19) that stimulates brown adipose tissue (BAT) thermogenic activity.

S6806 SBI-115 SBI-115 is a novel TGR5 (GPCR19) antagonist. SBI-115 decreases cell proliferation, cholangiocyte spheroid growth and cAMP levels in cystic cholangiocytes.
Cells, 2023, 12(4)526
Nat Commun, 2022, 13(1):3419
Research Square, 2021, 10.21203/rs.3.rs-274411/v1
S0193 TGR5 Receptor Agonist TGR5 Receptor Agonist (TGR5, CCDC, MDK00245, compd 6) is a potent agonist of TGR5(GPCR19, GPBAR1, M-BAR). TGR5 Receptor Agonist shows improved potency with pEC50 of 6.8 and 7.5 in the U2-OS cell assay and in melanophore cells, respectively.
Research Square, 2021, 10.21203/rs.3.rs-274411/v1
S0034 BAR501 BAR501 is a potent and selective G protein-coupled bile acid receptor 1 (GPBAR1, GPCR19, TGR5) agonist that effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1 with EC50 of 1 μM.
S2311 Hyodeoxycholic acid (HDCA) Hyodeoxycholic (HDCA, NSC 60672) acid is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria.
S6741 SB-756050 SB-756050 is a selective TGR5 agonist (EC50 = 1.3 μM for the human receptor).

Choose Selective GPCR19 Inhibitors

Tags: GPCR19 inhibitor|GPCR19 agonist|GPCR19 activator|GPCR19 inducer|GPCR19 antagonist|GPCR19 signaling pathway|GPCR19 assay kit