ARRY-382

Catalog No.S3570

For research use only.

ARRY-382 is a highly selective, oral inhibitor of the CSF1R with an IC50 of 9 nM.

ARRY-382 Chemical Structure

CAS No. 1313407-95-2

Purity & Quality Control

Choose Selective CSF-1R Inhibitors

Biological Activity

Description ARRY-382 is a highly selective, oral inhibitor of the CSF1R with an IC50 of 9 nM.
Targets
CSF1R [1]
9 nM

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 564.68
Formula

C32H36N8O2

CAS No. 1313407-95-2
Storage 3 years -20°C powder
2 years -80°C in solvent

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02880371 Terminated Drug: ARRY-382|Drug: Pembrolizumab Advanced Solid Tumors Pfizer September 1 2016 Phase 1|Phase 2

(data from https://clinicaltrials.gov, updated on 2022-11-29)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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