Ponatinib (AP24534)

For research use only.

Catalog No.S1490

120 publications

Ponatinib (AP24534) Chemical Structure

CAS No. 943319-70-8

Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively. Ponatinib (AP24534) inhibits autophagy.

Size Price Stock Quantity  
10mM (1mL in DMSO) USD 100 In stock
USD 110 In stock
USD 370 In stock
USD 970 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Selleck's Ponatinib (AP24534) has been cited by 120 publications

Purity & Quality Control

Choose Selective Bcr-Abl Inhibitors

Biological Activity

Description Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively. Ponatinib (AP24534) inhibits autophagy.
Targets
Abl [1]
(Cell-free assay)
PDGFRα [1]
(Cell-free assay)
VEGFR2 [1]
(Cell-free assay)
FGFR1 [1]
(Cell-free assay)
c-Src [1]
(Cell-free assay)
0.37 nM 1.1 nM 1.5 nM 2.2 nM 5.4 nM
In vitro

AP24534 potently inhibits native Abl, AblT315I, and other clinically important Abl kinase domain mutants with IC50 of 0.30 nM–2 nM. AP24534 doesn't inhibit Aurora kinase family members, nor does it inhibit insulin receptor or CDK2/cyclin E. AP24534 inhibits proliferation of Ba/F3 cells expressing Bcr-Abl with IC50 of 0.5 nM, as well as Ba/F3 cells expressing a range of Bcr-Abl mutants with IC50 of 0.5 nM–36 nM. The inhibition of proliferation by AP24534 is correlated with induction of apoptosis. [1-2] In leukemic cell lines containing activated forms of FLT3, KIT, FGFR1, and PDGFRα receptors, AP24534 potently inhibits receptor phosphorylation and cellular proliferation with IC50 of 0.3 nM to 20 nM. In MV4-11 (FLT3-ITD(+/+)) but not RS4;11 (FLT3-ITD(–/–)) AML cells, AP24534 inhibits FLT3 signaling and induced apoptosis at less than 10 nM. AP24534 inhibits viability of primary leukemic blasts from a FLT3-ITD positive AML patient with IC50 of 4 nM but not those from patients with AML expressing native FLT3. [3] In Ba/F3 cells engineered to express activated FGFR1-4, AP24534 potently inhibits FGFR-mediated signaling and viability with IC50 lower than 40 nM. In cell lines representing multiple tumor types (endometrial, bladder, gastric, breast, lung, and colon), and containing FGFRs dysregulated by a variety of mechanisms, AP24534 inhibits FGFR-mediated signaling with IC50 less than 40 nM and inhibits cell growth with IC50 of 7 nM–181 nM. [4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
EoL-1-cell M2rpS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVTJR|UxRTBwMECwNFAxODN3OTFOwG0> M3OzbHNCVkeHUh?=
MV-4-11 MojkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIjsfVFKSzVyPUCuNFAxODl3NjFOwG0> MljqV2FPT0WU
MEG-01 M372W2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFzrU2pKSzVyPUCuNFAxOTJ6IN88US=> Mm\ZV2FPT0WU
LAMA-84 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MofPTWM2OD1yLkCwNFE3PSEQvF2= M1fpd3NCVkeHUh?=
CGTH-W-1 NGrFVlJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWjxPGJCUUN3ME2wMlAxOTZ7IN88US=> NV3YeW5yW0GQR1XS
KASUMI-1 NWnrV4R6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEXFXYpKSzVyPUCuNFAzOTdizszN NGK2PGtUSU6JRWK=
BE-13 MmnaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXjJR|UxRTBwMECyOVkh|ryP NX:1SmQ1W0GQR1XS
CTV-1 M3HKOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NET4OlRKSzVyPUCuNFA2OjFizszN MY\TRW5ITVJ?
NKM-1 NFzD[2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF;nZpVKSzVyPUCuNFA3PTVizszN MYHTRW5ITVJ?
MONO-MAC-6 NYjxTo1mT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF7SdFhKSzVyPUCuNFA5OzdizszN MWjTRW5ITVJ?
A204 Mn\wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{XvNmlEPTB;MD6wNVIyQCEQvF2= NUO0XlZ3W0GQR1XS
GDM-1 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlS1TWM2OD1yLkCxPFM{KM7:TR?= Mmn6V2FPT0WU
AN3-CA MlTwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXjJR|UxRTBwMEG4O|Mh|ryP NISyOGdUSU6JRWK=
BL-70 NF7kWW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjWTWM2OD1yLkCyNVk6KM7:TR?= NHnJTnJUSU6JRWK=
Daudi MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkHTTWM2OD1yLkCyOVM4KM7:TR?= NXrYcmZjW0GQR1XS
KU812 NIjBWVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MULJR|UxRTBwMEK4OFgh|ryP MXrTRW5ITVJ?
KG-1 M2SzdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{LId2lEPTB;MD6wN|I6PCEQvF2= NU\wbJpzW0GQR1XS
DOHH-2 NVy4dZB6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlHpTWM2OD1yLkC0PFA{KM7:TR?= MYXTRW5ITVJ?
HuO9 NFrNUYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mon6TWM2OD1yLkC1OFQ5KM7:TR?= MmnoV2FPT0WU
EB2 NGDsN|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLiPI1KSzVyPUCuNFU2PzZizszN MYHTRW5ITVJ?
G-402 NGTrSVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3nENGlEPTB;MD6wOlM1OSEQvF2= NVTFV5A2W0GQR1XS
SU-DHL-1 MoXWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYPEflNtUUN3ME2wMlA3Ozd7IN88US=> M33WVHNCVkeHUh?=
NCI-H719 M2DpdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF\scYJKSzVyPUCuNFc5QDhizszN NWXCU2FEW0GQR1XS
MLMA M{XKNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmDHTWM2OD1yLkC5NFYh|ryP MlLKV2FPT0WU
KM12 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2q5OmlEPTB;MD6wPVc{PyEQvF2= M3jpUXNCVkeHUh?=
SUP-T1 NFe4dlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1XmSWlEPTB;MD6wPVk5OiEQvF2= NEewN|lUSU6JRWK=
MZ1-PC MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXLJR|UxRTBwMUGzN|Yh|ryP M1j3enNCVkeHUh?=
MFE-296 M2nLVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\3dmlEPTB;MD6xNVg{QSEQvF2= M{HwW3NCVkeHUh?=
ALL-PO NXS1V|gyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{DqRmlEPTB;MD6xNlQ1OyEQvF2= MVPTRW5ITVJ?
GB-1 NWHqfmZ1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlyyTWM2OD1yLkGyOVEzKM7:TR?= MVXTRW5ITVJ?
SIG-M5 MnL4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NInFZYpKSzVyPUCuNVM{PyEQvF2= NHjlNotUSU6JRWK=
P30-OHK MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFL5fFlKSzVyPUCuNVU3PzJizszN MYXTRW5ITVJ?
NCI-H716 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1PwVGlEPTB;MD6xOlI3PiEQvF2= M17CO3NCVkeHUh?=
MPP-89 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYfRcFFMUUN3ME2wMlE3QTN|IN88US=> MYrTRW5ITVJ?
SF126 MoHoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2nOUWlEPTB;MD6xO|A3OyEQvF2= M2DPbnNCVkeHUh?=
CTB-1 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYTJR|UxRTBwMUezNVYh|ryP MX3TRW5ITVJ?
CA46 NIDnSWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTBwMUe0PFkh|ryP NWfoZXhOW0GQR1XS
NCI-H520 NGD5SZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MknuTWM2OD1yLkG3O|MzKM7:TR?= MmS0V2FPT0WU
CAL-85-1 MmjlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnzvTWM2OD1yLkG3PVI4KM7:TR?= NInn[3FUSU6JRWK=
NCI-H2342 M{L4eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3G5fWlEPTB;MD6xPFU4PyEQvF2= M3TsbHNCVkeHUh?=
697 NWHTRpVxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3z6dGlEPTB;MD6xPFg4OSEQvF2= NI\XT2JUSU6JRWK=
NY NVHrTZI3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHrKRlFKSzVyPUCuNVkzQDdizszN M3\kR3NCVkeHUh?=
T98G NH6wS|ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3fXSGlEPTB;MD6xPVMyQCEQvF2= NYnHRoM3W0GQR1XS
NCI-H1703 NFLyc|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWTJR|UxRTBwMUm2NVUh|ryP NF7sO|dUSU6JRWK=
NCI-H2087 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUDJR|UxRTBwMkC0N|kh|ryP M2\nbXNCVkeHUh?=
PF-382 NF:2N5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NG\SfWdKSzVyPUCuNlA5PzNizszN MV\TRW5ITVJ?
HCT-116 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnnNTWM2OD1yLkKxNFY6KM7:TR?= MmLQV2FPT0WU
CAKI-1 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWTTSYtUUUN3ME2wMlIyPjZ4IN88US=> MoO1V2FPT0WU
CCF-STTG1 NV:1O2ZTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{nne2lEPTB;MD6yNlQ4PSEQvF2= MXHTRW5ITVJ?
D-392MG MlHYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlfLTWM2OD1yLkKzNVc4KM7:TR?= MYrTRW5ITVJ?
RT-112 NYX4dm1iT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTBwMkO3PVUh|ryP Ml;lV2FPT0WU
MES-SA MnjoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1HTdGlEPTB;MD6yOFE5PyEQvF2= MX\TRW5ITVJ?
LC-2-ad NWrUPXo4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYPURYRtUUN3ME2wMlI1OjZ3IN88US=> NUTYZW1iW0GQR1XS
NOS-1 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoL5TWM2OD1yLkK0N|Y4KM7:TR?= NUW4TnhpW0GQR1XS
NALM-6 MlfCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYe4VXkxUUN3ME2wMlI2PTR|IN88US=> NFfO[HVUSU6JRWK=
TE-15 NHy2NXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1HqN2lEPTB;MD6yOlA6OSEQvF2= MkjSV2FPT0WU
786-0 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVPGbXA3UUN3ME2wMlI3OjJ6IN88US=> MYTTRW5ITVJ?
IST-MES1 NUfk[pV6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGTrfYhKSzVyPUCuNlY5OjlizszN NHO3cHpUSU6JRWK=
KYSE-180 MljLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXfzXW82UUN3ME2wMlI3QDlzIN88US=> NXHSUHRzW0GQR1XS
YT NF;1ZmxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYfqUG94UUN3ME2wMlI3QTd2IN88US=> M3rjZXNCVkeHUh?=
A427 M4rpSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEP4N2dKSzVyPUCuNlczPjRizszN MVHTRW5ITVJ?
KYSE-450 MoS2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoDUTWM2OD1yLkK3N|I6KM7:TR?= MnnHV2FPT0WU
HuH-7 M1fnSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV;JR|UxRTBwMke3OlMh|ryP NEi2T|BUSU6JRWK=
CAS-1 MlfrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkewTWM2OD1yLkK4N|A{KM7:TR?= MULTRW5ITVJ?
KURAMOCHI NYnKOpRPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3;Wb2lEPTB;MD6yPFQyQSEQvF2= M1fKenNCVkeHUh?=
ACHN MnXuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW[1T2s6UUN3ME2wMlI6OzJ|IN88US=> MmDGV2FPT0WU
HGC-27 MmLJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEntNY1KSzVyPUCuNlk{PTNizszN NG\sbZBUSU6JRWK=
A172 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVfJR|UxRTBwMkm1O|ch|ryP MmKyV2FPT0WU
SNU-449 NUDCZY5[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXnoV|NuUUN3ME2wMlI6QTZ2IN88US=> MUnTRW5ITVJ?
SW982 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVTJR|UxRTBwMkm5O|gh|ryP NHvXPYxUSU6JRWK=
EFO-21 MnfoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MW\JR|UxRTBwM{C0NVEh|ryP NYf4[ZZtW0GQR1XS
NCI-H2030 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlLETWM2OD1yLkOxNVY1KM7:TR?= MmroV2FPT0WU
HT-144 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHyxOWlKSzVyPUCuN|EzQCEQvF2= M{C1fXNCVkeHUh?=
MFE-280 NFjHOZZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{foRWlEPTB;MD6zNVQ2OyEQvF2= M4rqTHNCVkeHUh?=
SK-LU-1 M1z6d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3K4PWlEPTB;MD6zNVQ3PiEQvF2= Mk[0V2FPT0WU
NCI-H2052 M1;MfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MW\JR|UxRTBwM{G0PFQh|ryP M2Xqb3NCVkeHUh?=
SK-HEP-1 NFrWNGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NI\R[|BKSzVyPUCuN|M{PjhizszN NFTUZ|RUSU6JRWK=
QIMR-WIL M1TUfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlT1TWM2OD1yLkOzOFI1KM7:TR?= M2XGVXNCVkeHUh?=
A2780 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXHJR|UxRTBwM{SzNFQh|ryP M4HaWHNCVkeHUh?=
ACN M2D5dmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1vjZ2lEPTB;MD6zOFg4OyEQvF2= M4XjVHNCVkeHUh?=
BxPC-3 NVPDcVJ5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3rSSGlEPTB;MD6zOFk5QSEQvF2= NYf4[VJVW0GQR1XS
BCPAP M2jHO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NW\WOlh2UUN3ME2wMlM3ODBzIN88US=> NU\Cd4t5W0GQR1XS
HOP-62 M4fQS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXL5PYU5UUN3ME2wMlM3OTB4IN88US=> MYDTRW5ITVJ?
SW1710 MoTwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3LnO2lEPTB;MD6zOlQ2PSEQvF2= M2jPRnNCVkeHUh?=
OPM-2 NWqyUVNuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWPQTYVPUUN3ME2wMlM3PDd|IN88US=> M4i3WHNCVkeHUh?=
DBTRG-05MG NFv1SIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUDJR|UxRTBwM{iwOVQh|ryP NH7hRYZUSU6JRWK=
SK-MEL-24 NULXSolWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVfBXFd2UUN3ME2wMlM6PzlzIN88US=> MnvoV2FPT0WU
8305C NXO1XmxpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml;jTWM2OD1yLkO5O|k{KM7:TR?= MW\TRW5ITVJ?
OVCAR-4 NHO1eXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEjoTJJKSzVyPUCuOFE2QDZizszN NXf5cHo4W0GQR1XS
HLE NWrEflRmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHe2OWxKSzVyPUCuOFE5PiEQvF2= NHTkcWxUSU6JRWK=
NCI-H747 NGezU2pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIfEW3hKSzVyPUCuOFIyOzdizszN NWfOd|czW0GQR1XS
SW780 NHe3cVFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV3JR|UxRTBwNEKzOFYh|ryP NGTTU|RUSU6JRWK=
KYSE-150 NHrjNJZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYrJR|UxRTBwNEK0NVUh|ryP NFHjcohUSU6JRWK=
H4 MnrwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NI\hfYhKSzVyPUCuOFI1PTFizszN MXXTRW5ITVJ?
SW1088 M1e4S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4e5V2lEPTB;MD60OFM6KM7:TR?= NXGxWoFCW0GQR1XS
SF268 NU\ZfHg{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFHFS3VKSzVyPUCuOFQ5PiEQvF2= NXzFeFIxW0GQR1XS
RT4 NFjvd4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoDTTWM2OD1yLkS1NVEyKM7:TR?= MUnTRW5ITVJ?
NCI-H522 NHnROpBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFz2NWNKSzVyPUCuOFUzPyEQvF2= NIP6fWlUSU6JRWK=
LCLC-97TM1 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3HPdmlEPTB;MD60OlE6PSEQvF2= M1TvSHNCVkeHUh?=
CAL-39 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4TKWGlEPTB;MD60OlUyQSEQvF2= MUHTRW5ITVJ?
CAL-120 NHTlNFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnixTWM2OD1yLkS3OlQ{KM7:TR?= NUG4OXhCW0GQR1XS
ESS-1 NWPIOI5[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmjvTWM2OD1yLkS3PFIyKM7:TR?= MVnTRW5ITVJ?
KARPAS-45 Moj4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn;lTWM2OD1yLkS4PVM{KM7:TR?= NWPLSppPW0GQR1XS
DU-4475 NEPzUmRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4TPWGlEPTB;MD60PVUyOSEQvF2= M{\kXHNCVkeHUh?=
VMRC-RCZ NIDmO3pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkDNTWM2OD1yLkS5PVA1KM7:TR?= NHK3TXhUSU6JRWK=
HOS M{Lqfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm\ITWM2OD1yLkWwN|Y2KM7:TR?= MlrVV2FPT0WU
MOLT-16 MkfiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF3HdYZKSzVyPUCuOVE5ODhizszN MXfTRW5ITVJ?
RPMI-6666 M33u[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2rVVGlEPTB;MD61NlE{PSEQvF2= MVPTRW5ITVJ?
K052 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYrpSlBGUUN3ME2wMlUzOTRizszN NFXxOnhUSU6JRWK=
EHEB M1iwTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1mxTWlEPTB;MD61NlE5OiEQvF2= M1GybHNCVkeHUh?=
MFH-ino M2jhZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGfHWGNKSzVyPUCuOVI{PTFizszN NUXBPHBPW0GQR1XS
A4-Fuk NXm3NlNrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXewUIMxUUN3ME2wMlUzPTJ6IN88US=> MniyV2FPT0WU
SW1417 Ml\JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MY\JR|UxRTBwNUK3PFEh|ryP MlrDV2FPT0WU
DoTc2-4510 NF3mPJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlLnTWM2OD1yLkW0PVU5KM7:TR?= NWHkcIx{W0GQR1XS
TE-12 M3XwV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmHlTWM2OD1yLkW1O|M2KM7:TR?= NFPIbJJUSU6JRWK=
8-MG-BA NFeyZm5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnW4TWM2OD1yLkW2NFU3KM7:TR?= NVfzZ3FYW0GQR1XS
ECC12 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYDJR|UxRTBwNU[1OVgh|ryP MWfTRW5ITVJ?
CHL-1 MojIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWqwPJh[UUN3ME2wMlU4PDZ|IN88US=> NYPOWHBtW0GQR1XS
LCLC-103H NGG5ZlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjOTWM2OD1yLkW4N|Q1KM7:TR?= MUfTRW5ITVJ?
OS-RC-2 M3H4Wmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTBwNUizO|kh|ryP MmqxV2FPT0WU
RO82-W-1 M{fMfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoDPTWM2OD1yLkW5OlE2KM7:TR?= MWXTRW5ITVJ?
A3-KAW NWD3[4YzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJR|UxRTBwNkG0Olch|ryP NGTIO4JUSU6JRWK=
NCCIT MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmW5TWM2OD1yLk[xO|E2KM7:TR?= M3ryenNCVkeHUh?=
IST-SL2 M3jJdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn:1TWM2OD1yLk[yOVIzKM7:TR?= MkTlV2FPT0WU
GI-ME-N MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHjOU4FKSzVyPUCuOlMxPjlizszN MlvXV2FPT0WU
ES6 NF72V2tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXW3XlE4UUN3ME2wMlY{Ojl3IN88US=> NV3PTZBZW0GQR1XS
BL-41 M{TtV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MY\JR|UxRTBwNkOzOVIh|ryP NV7OPIhZW0GQR1XS
Ca-Ski NYDUSYNzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3;3TmlEPTB;MD62OFgyKM7:TR?= Mn\LV2FPT0WU
HOP-92 Ml;NS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUS2PVUyUUN3ME2wMlY2Pjd{IN88US=> Mm\oV2FPT0WU
SK-LMS-1 NGPxfJNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXTFUlk2UUN3ME2wMlY3PDdizszN NIHKSXhUSU6JRWK=
EW-13 MnPuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUnsSHJbUUN3ME2wMlY3Pzd7IN88US=> M3HKZ3NCVkeHUh?=
647-V Mmn1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MY\JR|UxRTBwNkixOFgh|ryP NYXtbIJrW0GQR1XS
JiyoyeP-2003 NFHDUHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3PHXGlEPTB;MD62PVc{QCEQvF2= M365UHNCVkeHUh?=
WSU-NHL M3HYZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmLRTWM2OD1yLkewPFg4KM7:TR?= MkOzV2FPT0WU
U-698-M MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXn5[FdNUUN3ME2wMlcyODZ|IN88US=> NYX6[mRtW0GQR1XS
HC-1 MkO0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVLJR|UxRTBwN{K0NFUh|ryP NID6U2pUSU6JRWK=
8505C MmfBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{K1[2lEPTB;MD63Nlc1OSEQvF2= MY\TRW5ITVJ?
HUTU-80 NE[4THRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnvqTWM2OD1yLkezN|Q6KM7:TR?= NGO2bmVUSU6JRWK=
LB1047-RCC MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHXwPGdKSzVyPUCuO|M2OzhizszN NHr3UolUSU6JRWK=
GAMG NVPze2Z5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXn5b|FoUUN3ME2wMlc{PjV|IN88US=> Mn22V2FPT0WU
CAL-12T MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NU\rTlVEUUN3ME2wMlc{QDd5IN88US=> NYfx[WdMW0GQR1XS
NCI-SNU-1 NIS1bJFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkLTTWM2OD1yLke3Nlc5KM7:TR?= M3zjb3NCVkeHUh?=
HTC-C3 NFrxUmRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{C0ZWlEPTB;MD63O|Q2OSEQvF2= MV\TRW5ITVJ?
HPAF-II MkDwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTBwN{e1NFEh|ryP MWrTRW5ITVJ?
KGN MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHzkNXRKSzVyPUCuO|gxQDFizszN MYHTRW5ITVJ?
EFO-27 MmfXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4\UT2lEPTB;MD63PFc{OyEQvF2= NUDZUXQ3W0GQR1XS
MEL-HO NG\4WYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NY\KbGtEUUN3ME2wMlc6PDR7IN88US=> MmDSV2FPT0WU
KYSE-270 NGH1NZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFrue5BKSzVyPUCuPFA2OjlizszN NVPqcZhKW0GQR1XS
NCI-H1755 NWTZb5ZpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkW4TWM2OD1yLkiwO|E1KM7:TR?= NWrjd4t4W0GQR1XS
MFM-223 MmPxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXXJR|UxRTBwOEG0NFch|ryP MWfTRW5ITVJ?
G-361 M{nJSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkLLTWM2OD1yLkixPFk4KM7:TR?= M{nTRnNCVkeHUh?=
ETK-1 NFTwe3pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYXJR|UxRTBwOEK0OFEh|ryP NI\p[oRUSU6JRWK=
LU-99A MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3XNN2lEPTB;MD64OFcxOSEQvF2= M1q3NnNCVkeHUh?=
IST-MEL1 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MorxTWM2OD1yLki1O|MzKM7:TR?= MXPTRW5ITVJ?
L-540 MnzzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFrIUYtKSzVyPUCuPFU5ODFizszN NHXyZZJUSU6JRWK=
U-2-OS NV;zWmdET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI\mUXZKSzVyPUCuPFU5PDZizszN NIjBTXVUSU6JRWK=
HT-1376 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlPLTWM2OD1yLki2NFUyKM7:TR?= MV\TRW5ITVJ?
COLO-680N M4PHNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn\LTWM2OD1yLki3PVM{KM7:TR?= MXLTRW5ITVJ?
NCI-H1581 Ml[3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2[0R2lEPTB;MD64PVI6PyEQvF2= MlewV2FPT0WU
HuCCT1 MmPNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGnqdYhKSzVyPUCuPFk2PDhizszN MnrvV2FPT0WU
BB30-HNC MlWwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\jTWM2OD1yLkmyOFY6KM7:TR?= MlTkV2FPT0WU
NCI-H2347 M1TTZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGTMOoRKSzVyPUCuPVMzQTJizszN M2H6cHNCVkeHUh?=
G-401 Mnq4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXfNXXQ2UUN3ME2wMlk{Pjl3IN88US=> NEnxbWVUSU6JRWK=
NCI-H358 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{XrbmlEPTB;MD65OVAyPCEQvF2= MXPTRW5ITVJ?
HCC1395 Mlr3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFXrPFBKSzVyPUCuPVU1PjFizszN M1[2U3NCVkeHUh?=
J82 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1\oUmlEPTB;MD65OVU1OyEQvF2= Mnv5V2FPT0WU
KE-37 NE\KbnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4nmRmlEPTB;MD65OlM5PyEQvF2= NIjFdZhUSU6JRWK=
NOMO-1 NX;KTFJkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnX6TWM2OD1yLkm2OVY1KM7:TR?= MVHTRW5ITVJ?
ML-2 MlvQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkHvTWM2OD1yLkm5O|Uh|ryP M4S1TnNCVkeHUh?=
SW872 M3LzPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkHZTWM2OD1yLkm5O|c2KM7:TR?= NUXr[m9wW0GQR1XS
KYSE-520 MnjaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH7sUZlKSzVyPUGuNFA1QTRizszN MorQV2FPT0WU
HL-60 NGOzb|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWHNUpl6UUN3ME2xMlAxQTdizszN NFTpPYJUSU6JRWK=
HDLM-2 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlnlTWM2OD1zLkCxNlUzKM7:TR?= Mm\nV2FPT0WU
MIA-PaCa-2 NWW3PIxiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NW\LUVNNUUN3ME2xMlAyOzd3IN88US=> NXXxeZBqW0GQR1XS
TCCSUP Mn7US5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn3JTWM2OD1zLkCxO|MzKM7:TR?= M3ywN3NCVkeHUh?=
SH-4 MkPOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkLsTWM2OD1zLkCyNlQ1KM7:TR?= M1XDV3NCVkeHUh?=
MG-63 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1;XbGlEPTB;MT6wNlYyPiEQvF2= NFOybYVUSU6JRWK=
NB6 NVHQZW03T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYLJR|UxRTFwMEOxNFkh|ryP NWf5bXNKW0GQR1XS
CAL-54 NXjwXms3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVPJR|UxRTFwMEO5OVkh|ryP MULTRW5ITVJ?
DU-145 MlXzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MU\JR|UxRTFwMEiwO|Mh|ryP MWjTRW5ITVJ?
HCE-4 M3;WZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn2yTWM2OD1zLkC5Nlg3KM7:TR?= MnPHV2FPT0WU
U-266 M4nUUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoXPTWM2OD1zLkC5OlM{KM7:TR?= M17TPHNCVkeHUh?=
HT-1197 MlXBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NY\0UpY1UUN3ME2xMlEyPDN6IN88US=> M4n1dnNCVkeHUh?=
EW-1 MoPvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHrsZ5RKSzVyPUGuNVQyOjhizszN NF7t[o9USU6JRWK=
MHH-NB-11 NHixSWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MY\JR|UxRTFwMUWzOlgh|ryP NIq5S|lUSU6JRWK=
NCI-H2405 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MofNTWM2OD1zLkG2NVYh|ryP M2[4[HNCVkeHUh?=
COLO-668 M1XIWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkPRTWM2OD1zLkG2OFkh|ryP MYHTRW5ITVJ?
IMR-5 M3zlS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVfkT|ZoUUN3ME2xMlE3QTN4IN88US=> MVXTRW5ITVJ?
ARH-77 M3LuXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37G[2lEPTB;MT6yNlkzPCEQvF2= NVrQTZBwW0GQR1XS
BHT-101 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH3yeoFKSzVyPUGuNlM1QSEQvF2= MlrjV2FPT0WU
SCC-25 NUDBc|YyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MULJR|UxRTFwMkO1N|Yh|ryP MVXTRW5ITVJ?
NTERA-S-cl-D1 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1joUGlEPTB;MT6yOFM1PiEQvF2= NF3EWWdUSU6JRWK=
MKN28 NIPlPFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYHJR|UxRTFwMkW2N|Yh|ryP M3vsXHNCVkeHUh?=
KS-1 NWft[pBTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEnJ[5BKSzVyPUGuNlgzPjlizszN MnXZV2FPT0WU
NCI-H1734 Ml7LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFvGSlhKSzVyPUGuNlg6OTNizszN MmjYV2FPT0WU
ES7 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWXJR|UxRTFwMkm1OFIh|ryP NH3qbZVUSU6JRWK=
NCI-H838 M1LCcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkmyTWM2OD1zLkOwOlE2KM7:TR?= MmjrV2FPT0WU
HEC-1 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEK5NY1KSzVyPUGuN|M4PTVizszN NGW5XVNUSU6JRWK=
ME-180 M3XOfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHfqbphKSzVyPUGuN|c6QTNizszN MVzTRW5ITVJ?
MMAC-SF NU\SOZBXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2rJdmlEPTB;MT6zPVU6PSEQvF2= NFrWOnRUSU6JRWK=
IA-LM MlKwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFLFcWlKSzVyPUGuOFA6OTRizszN MX3TRW5ITVJ?
MN-60 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmPZTWM2OD1zLkSzNVE1KM7:TR?= NGn1bXFUSU6JRWK=
SIMA MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXXJR|UxRTFwNEi2PFch|ryP NWDoW4d{W0GQR1XS
NCI-H1770 NVL4d2FJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkH1TWM2OD1zLkWyNFU1KM7:TR?= M3PIVXNCVkeHUh?=
ONS-76 NV\qO2dZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4P5XmlEPTB;MT61NlMyOSEQvF2= M2LNUHNCVkeHUh?=
LB771-HNC MnnrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWjVeWo6UUN3ME2xMlU{QTB4IN88US=> NIn0R|JUSU6JRWK=
SW48 NHPjOodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWDJR|UxRTFwNUSyOFMh|ryP M{\iOnNCVkeHUh?=
KYSE-140 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWHJR|UxRTFwNUW3OFEh|ryP NULmeIVtW0GQR1XS
SW626 NV;WO2p[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnXCTWM2OD1zLkW4NVYh|ryP NUPsNmI6W0GQR1XS
MC-CAR M1HCOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml21TWM2OD1zLkW4OlY{KM7:TR?= M3XSW3NCVkeHUh?=
D-336MG NVfiOY5VT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYP2dXF[UUN3ME2xMlYzQTRizszN MYLTRW5ITVJ?
SK-MEL-3 NIH1[|VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPkUYVVUUN3ME2xMlY{QTB{IN88US=> MWrTRW5ITVJ?
MHH-PREB-1 M1nke2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3frO2lEPTB;MT62OFQ4OyEQvF2= NYnJTVl[W0GQR1XS
Calu-1 MoPSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmfWTWM2OD1zLk[1N|g3KM7:TR?= MmDvV2FPT0WU
HCC1806 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkTFTWM2OD1zLk[2OlEyKM7:TR?= MkHoV2FPT0WU
A101D NH;JOo1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3vmfWlEPTB;MT62Olc5OSEQvF2= MXfTRW5ITVJ?
A704 M2jQZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXHJR|UxRTFwNkizNVEh|ryP MXTTRW5ITVJ?
LB831-BLC M{OxPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2L0RWlEPTB;MT62PVg2PCEQvF2= MnjVV2FPT0WU
RL95-2 MnfhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{PPbGlEPTB;MT63NVQ3OyEQvF2= NFjLVGNUSU6JRWK=
RPMI-2650 M3XFcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlfMTWM2OD1zLkeyO|E6KM7:TR?= MV7TRW5ITVJ?
NH-12 NWPqS5ptT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVr0SHNsUUN3ME2xMlc{PDJ5IN88US=> MU\TRW5ITVJ?
AGS NIDrfG9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlXlTWM2OD1zLke2N|U5KM7:TR?= NHzRRmlUSU6JRWK=
NEC8 NYXvZ5VxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NG\ae5lKSzVyPUGuO|g6QTVizszN M4DDXXNCVkeHUh?=
NCI-H2009 NUjWOVFFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWnVUWJHUUN3ME2xMlc6PzJzIN88US=> MV3TRW5ITVJ?
A498 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{XKU2lEPTB;MT64NVI5OiEQvF2= MU\TRW5ITVJ?
NCI-H810 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYHCWJNQUUN3ME2xMlgyPjB4IN88US=> NE\1SY1USU6JRWK=
SK-NEP-1 NGfmUGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4O3T2lEPTB;MT64N|c3PyEQvF2= M4e4SnNCVkeHUh?=
D-542MG MkOzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXviOVFVUUN3ME2xMlg2QDVzIN88US=> Mkn4V2FPT0WU
KNS-42 NVXRZ|BVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWnXRnk{UUN3ME2xMlg3OjZ4IN88US=> MWDTRW5ITVJ?
NCI-H2452 NXvFVolrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXfZZY9jUUN3ME2xMlg6ODd2IN88US=> MW\TRW5ITVJ?
SK-MEL-2 NYHGUI1XT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmfDTWM2OD1zLkmwNlcyKM7:TR?= NXfk[5d[W0GQR1XS
OVCAR-5 MkK0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4K0NWlEPTB;MT65NFY4PSEQvF2= NUTYR4ppW0GQR1XS
SNG-M MkfTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGP3U|BKSzVyPUGuPVU5PThizszN NH3lSJBUSU6JRWK=
A673 M4T6bWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1X6N2lEPTB;MT65O|UyPiEQvF2= NXTTSZB4W0GQR1XS
L-428 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGTaSWJKSzVyPUGuPVkyPzlizszN MonqV2FPT0WU
KM-H2 MoT2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoTYTWM2OD1{LkCxNFkh|ryP MmTzV2FPT0WU
MC-IXC NI[xW4xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYTE[FVpUUN3ME2yMlAzOjd|IN88US=> NUf1NpE4W0GQR1XS
COLO-678 NF;qPYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2LrO2lEPTB;Mj6wOFIxPyEQvF2= MX7TRW5ITVJ?
MEL-JUSO M4nEZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkTuTWM2OD1{LkC3PFUyKM7:TR?= MnXLV2FPT0WU
HCC38 M4fxU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX7jO4dqUUN3ME2yMlA5PDN|IN88US=> M2D1[3NCVkeHUh?=
UACC-62 MlL5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTJwMEi4OVUh|ryP NGfoOWlUSU6JRWK=
OAW-42 M{L3UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NW\rNoc6UUN3ME2yMlA6PzFzIN88US=> M2LNXHNCVkeHUh?=
LB996-RCC MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXqwPVNCUUN3ME2yMlE{QDF5IN88US=> MmjvV2FPT0WU
COR-L105 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4jBfGlEPTB;Mj6xOlM4OyEQvF2= M3zHUHNCVkeHUh?=
RCC10RGB NVTKS4lNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTJwMUi1O|Yh|ryP NVrKVXhTW0GQR1XS
A431 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYm3enFqUUN3ME2yMlE6ODF7IN88US=> NHHLeoZUSU6JRWK=
NCI-H292 M3XaNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXjL[Zo5UUN3ME2yMlI{QTVzIN88US=> M4fO[XNCVkeHUh?=
SK-UT-1 NVTvN|RVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFfkXWxKSzVyPUKuN|MyQDRizszN NIfP[4pUSU6JRWK=
PANC-08-13 NYP6UIZ6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX\JR|UxRTJwM{OyN|Uh|ryP MXnTRW5ITVJ?
ST486 MkLDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4HITWlEPTB;Mj60NVA1QCEQvF2= MXrTRW5ITVJ?
SJSA-1 NYrNdHR7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHHU[JlKSzVyPUKuOFEzPzFizszN MX7TRW5ITVJ?
RKO NFT3UZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlTqTWM2OD1{LkSyNFI6KM7:TR?= NYPkNIc5W0GQR1XS
NCI-H1793 Moi4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkPETWM2OD1{LkS0NFI6KM7:TR?= MlvkV2FPT0WU
639-V NGPmcVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\UcmlEPTB;Mj60OVM5OiEQvF2= MWLTRW5ITVJ?
ES3 M3jyeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF:2eZpKSzVyPUKuOFk4OzdizszN MVrTRW5ITVJ?
NCI-H1792 MlfmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M365RWlEPTB;Mj61OlgzPiEQvF2= NWftdXJCW0GQR1XS
NCI-H1651 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIjG[VFKSzVyPUKuOVgzOSEQvF2= NIPadXNUSU6JRWK=
SN12C MnHwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWLJR|UxRTJwNUi0PFch|ryP M1zoSHNCVkeHUh?=
COLO-679 NFntelFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mne0TWM2OD1{LkW4OlA2KM7:TR?= NIHpc5RUSU6JRWK=
U-118-MG M2qxUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1XsSmlEPTB;Mj61PFg4OiEQvF2= M1z1O3NCVkeHUh?=
Ramos-2G6-4C10 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1XHNGlEPTB;Mj62OFgxPyEQvF2= MY\TRW5ITVJ?
HCT-15 M2jJTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NE\zXHhKSzVyPUKuOlg4QTJizszN MX7TRW5ITVJ?
MDA-MB-157 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{TNNWlEPTB;Mj63NFc1PyEQvF2= MVHTRW5ITVJ?
K5 MmLtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MonoTWM2OD1{LkexPFQ2KM7:TR?= M2HoTXNCVkeHUh?=
MKN45 Mo\sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnvS2dKSzVyPUKuO|M{PjZizszN MkfzV2FPT0WU
DMS-273 M1zpW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXLJfZNvUUN3ME2yMlc2PjN{IN88US=> NILtc2VUSU6JRWK=
C8166 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2L1XmlEPTB;Mj63PFUyOyEQvF2= MnWzV2FPT0WU
Calu-3 M3TYRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXTvWoVOUUN3ME2yMlc5QTZ7IN88US=> MUjTRW5ITVJ?
SNB75 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4rEcmlEPTB;Mj64PFU{PSEQvF2= MW\TRW5ITVJ?
BFTC-905 NYDZNIFGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4izXmlEPTB;Mj65NFE6OSEQvF2= MXXTRW5ITVJ?
C-4-II NULpSZVUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjt[GlKSzVyPUKuPVE{PTNizszN NVPWPGtYW0GQR1XS
MS-1 NWD1Ro54T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX7JR|UxRTJwOU[3Olkh|ryP MnrKV2FPT0WU
A375 NXnoSYFYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUPJR|UxRTNwMEixPFQh|ryP M2GwdHNCVkeHUh?=
KYSE-70 NUn0enNWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYPRd3M2UUN3ME2zMlA5QDh{IN88US=> NVLzdGx5W0GQR1XS
KYSE-510 NXXQNHZxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2HwbGlEPTB;Mz6xNFk6PSEQvF2= NYjEVlVYW0GQR1XS
LN-405 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M33ie2lEPTB;Mz6xN|UyQCEQvF2= Ml74V2FPT0WU
BOKU NV24d4d{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVrJR|UxRTNwMUSyOVYh|ryP M3nwTHNCVkeHUh?=
TE-10 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEKweYNKSzVyPUOuNVc{PjJizszN MkKwV2FPT0WU
MKN1 NYHFfWYzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFLQVFRKSzVyPUOuNVg1QDNizszN MkC0V2FPT0WU
M059J NF7t[45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1OxNmlEPTB;Mz6yNFE4OyEQvF2= NEPxWIxUSU6JRWK=
GOTO NHTLVFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3IWpZSUUN3ME2zMlIzODN7IN88US=> MkPCV2FPT0WU
DK-MG NV;4VGlYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mon1TWM2OD1|LkK1PVc3KM7:TR?= NVi3dHV3W0GQR1XS
NCI-H727 NUfINolCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NY\Bb3NYUUN3ME2zMlI3PThizszN MoXTV2FPT0WU
NB12 NX3hRmhNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnHBTWM2OD1|LkOzNlI1KM7:TR?= NEn2NmtUSU6JRWK=
DOK M2\xfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlS2TWM2OD1|LkO2NVg3KM7:TR?= MWLTRW5ITVJ?
KYSE-410 NF;YbHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NILBUppKSzVyPUOuN|YzQDdizszN NG\BcnJUSU6JRWK=
AM-38 M3XtU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1zLZ2lEPTB;Mz6zPFA2OSEQvF2= NHrGXm9USU6JRWK=
GR-ST NWriVnBST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWO5SlhwUUN3ME2zMlQ2PzN{IN88US=> MVzTRW5ITVJ?
D-247MG MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGrYSY9KSzVyPUOuOFgzPjNizszN MXXTRW5ITVJ?
TE-8 M1vWSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1vNS2lEPTB;Mz60PVM{OyEQvF2= MYrTRW5ITVJ?
LS-411N NGezUXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYq4VGl7UUN3ME2zMlQ6Pjl{IN88US=> M3vPZXNCVkeHUh?=
SK-MES-1 NGHLTY5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{\je2lEPTB;Mz61OlQ{OyEQvF2= MV;TRW5ITVJ?
SF295 M2XzUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH7PN5BKSzVyPUOuOlE2PTJizszN MnS1V2FPT0WU
SK-MEL-30 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYTLZYVmUUN3ME2zMlY2QTJzIN88US=> MlnTV2FPT0WU
LB2241-RCC MontS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHTBSWhKSzVyPUOuOlYzPiEQvF2= NVzhVGE1W0GQR1XS
PC-14 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M130cmlEPTB;Mz62OlQ{PyEQvF2= NY[1XFBkW0GQR1XS
EW-7 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEG3eFVKSzVyPUOuOlc3QTNizszN MVrTRW5ITVJ?
NMC-G1 NGHIcHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmT1TWM2OD1|LkexPFM4KM7:TR?= NXzyWnEyW0GQR1XS
TE-441-T MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mkj1TWM2OD1|LkezNFI5KM7:TR?= NWHV[I5mW0GQR1XS
NCI-H1618 M1TWUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTNwOEG4O|Uh|ryP NYDlcVRpW0GQR1XS
PANC-03-27 M4W2VWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGTlPXZKSzVyPUOuPFE6OTZizszN MorLV2FPT0WU
NCI-H2228 MonHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlWwTWM2OD1|LkizNVI3KM7:TR?= MWfTRW5ITVJ?
CAPAN-1 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYDJR|UxRTNwOEewNFkh|ryP M3nYb3NCVkeHUh?=
KLE MorkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWPJR|UxRTNwOUC2O{DPxE1? M3q5bHNCVkeHUh?=
Becker MnfsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnX3TWM2OD1|LkmyPFQ6KM7:TR?= MX;TRW5ITVJ?
SK-PN-DW NX\PSo9ET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlztTWM2OD12LkC3PVc1KM7:TR?= MYXTRW5ITVJ?
Hs-578-T MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlTsTWM2OD12LkC4N|A3KM7:TR?= NInMenRUSU6JRWK=
RS4-11 M3ewWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHL2RZRKSzVyPUSuNVEzPTVizszN NIfMWY5USU6JRWK=
D-502MG NIT2fldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoDmTWM2OD12LkG2PVk4KM7:TR?= NYrQOGJqW0GQR1XS
GI-1 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH[weHdKSzVyPUSuNlgzQTlizszN M1jtdnNCVkeHUh?=
NCI-H209 MlPCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEn2c2ZKSzVyPUSuN|M4QCEQvF2= NGizVndUSU6JRWK=
SK-OV-3 M{LVUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTRwNEixOFkh|ryP NF;TPHdUSU6JRWK=
LOUCY NVHQcGU3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHvLfJhKSzVyPUSuOFg1OzJizszN NFXXUFJUSU6JRWK=
NCI-H69 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYPJR|UxRTRwNUG3PVMh|ryP NH3RNHdUSU6JRWK=
SCC-9 MmnRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTRwNUOxO|Ih|ryP MnzkV2FPT0WU
NCI-H526 NVnzZ2ZZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlfkTWM2OD12LkW5Nlk{KM7:TR?= MkLzV2FPT0WU
NCI-H2170 MnG2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYPQZ|k6UUN3ME20MlY3PzdzIN88US=> NH7QfGpUSU6JRWK=
SR MmfHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVjuSoJHUUN3ME20MlcxODR6IN88US=> M2r0fnNCVkeHUh?=
CMK NFLVZlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXnJR|UxRTRwN{KxNFEh|ryP M1LuO3NCVkeHUh?=
COLO-829 NWrKfm1HT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlL4TWM2OD12Lke3NFQ{KM7:TR?= NVXlb2JbW0GQR1XS
HuO-3N1 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYPJR|UxRTRwOEOyPFEh|ryP M4\0NHNCVkeHUh?=
5637 M2S0Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NULt[5ZMUUN3ME20MlkxPDh5IN88US=> M4fEWnNCVkeHUh?=
A253 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NY\PfItYUUN3ME20Mlk4PzB6IN88US=> NHq3R41USU6JRWK=
NB10 M2jKXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{nMRWlEPTB;NT6wO|Q6PyEQvF2= M1jKdnNCVkeHUh?=
SF539 NGHXRWRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{HHeWlEPTB;NT6wPVk2QSEQvF2= M1jyOHNCVkeHUh?=
HAL-01 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1i5WmlEPTB;NT6xOFY1PSEQvF2= NVuwNINuW0GQR1XS
MHH-ES-1 M{D0TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYPJR|UxRTVwMU[5NlUh|ryP M2HIZ3NCVkeHUh?=
DEL NGTNPVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTVwMke1PFIh|ryP NGjnT2dUSU6JRWK=
NCI-H1299 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYfCd5ZpUUN3ME21MlM2ODB5IN88US=> NX3TW5dbW0GQR1XS
ChaGo-K-1 M4DOb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4juVGlEPTB;NT6zOVExPyEQvF2= MV\TRW5ITVJ?
HMV-II NXXqOFd3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX;wbIdVUUN3ME21MlM6PDNizszN M33tXnNCVkeHUh?=
NB69 NGPRSpZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHzPS49KSzVyPUWuN|k3OzFizszN NYLMOZJVW0GQR1XS
NCI-H1882 MoHYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX3JR|UxRTVwNEOzOlQh|ryP MXnTRW5ITVJ?
SNU-475 NFPERopIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3X3TGlEPTB;NT60O|E4OSEQvF2= M3O2WnNCVkeHUh?=
RXF393 NVqwc3E{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX65Xo9yUUN3ME21MlQ5PDl2IN88US=> M2O1WXNCVkeHUh?=
CAL-51 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkW2TWM2OD13Lk[yPFU{KM7:TR?= NUjNT|h2W0GQR1XS
SW1573 NUmyXJVDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlHUTWM2OD13Lk[zOVM1KM7:TR?= NFzPPW5USU6JRWK=
GCT NFfiWJZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXi4e3pnUUN3ME21Mlc2QTJ7IN88US=> MWjTRW5ITVJ?
COR-L88 MkS5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnjiTWM2OD13Lke2PFQ3KM7:TR?= MWPTRW5ITVJ?
MDA-MB-134-VI NWjCe4FsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkjiTWM2OD13Lki3OVM3KM7:TR?= NHS1cFdUSU6JRWK=
NB5 NX7Jd25lT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJR|UxRTVwOUK0OEDPxE1? MkS2V2FPT0WU
GMS-10 M2j1[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTVwOU[4OlEh|ryP NWnBdXFCW0GQR1XS
CHP-212 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlLCTWM2OD14LkS4NlY4KM7:TR?= NH\IPIpUSU6JRWK=
TE-11 NY\tNopKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{PPVmlEPTB;Nj61OVE5OiEQvF2= NWTXWZMxW0GQR1XS
SW962 NYrsdW1YT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHntW4ZKSzVyPU[uOlU4PzRizszN MV\TRW5ITVJ?
MZ2-MEL MmDvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2XyO2lEPTB;Nj64NlAyOSEQvF2= NXv2OWhJW0GQR1XS
C-33-A NHrH[2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEfvd2FKSzVyPU[uPVE3QDhizszN MnT2V2FPT0WU
IGR-1 M4rheGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTZwOUe4NlYh|ryP NWLKVIQ5W0GQR1XS
MOLT-4 M4LD[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXv4e3lSUUN3ME23MlE2PDB4IN88US=> MojNV2FPT0WU
NCI-H1650 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHxTWM2OD15LkK3NFQ3KM7:TR?= MUDTRW5ITVJ?
AsPC-1 NEfTXoRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{XjeGlEPTB;Nz6yPFYxPSEQvF2= MnHzV2FPT0WU
SNU-C2B M4HxfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVPaN3RRUUN3ME23MlI6PTdzIN88US=> NGL2WZpUSU6JRWK=
MKN7 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4nHS2lEPTB;Nz6zO|I{PSEQvF2= NGrJSW9USU6JRWK=
SW620 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUjJR|UxRTdwM{iyNFUh|ryP Mn;oV2FPT0WU
SK-MEL-28 MkDkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4H4S2lEPTB;Nz60NFc6QCEQvF2= NGfVU|JUSU6JRWK=
TE-6 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYTJR|UxRTdwNES5NFgh|ryP NFHXblJUSU6JRWK=
D-263MG M4TafGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV2yXVBSUUN3ME23MlQ2PzZ{IN88US=> M1n6T3NCVkeHUh?=
NCI-H1355 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXi0SGFUUUN3ME23Mlc4ODJ7IN88US=> M3jjU3NCVkeHUh?=
DSH1 NH\SUphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWHJR|UxRTdwN{m3OlIh|ryP NIW3R2xUSU6JRWK=
NCI-H460 NWf4c2dXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnSwTWM2OD16LkCwOlk1KM7:TR?= M1nPNXNCVkeHUh?=
NCI-H1563 NIDQeXFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX21cmxNUUN3ME24MlA4PTB6IN88US=> NHTzSW5USU6JRWK=
SW948 Mn;ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlraTWM2OD16LkGwO|Q1KM7:TR?= M4XYR3NCVkeHUh?=
LK-2 M3zNZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIP1coNKSzVyPUiuNVI5OzNizszN MlOyV2FPT0WU
HT-1080 NWLSWpdoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHO0T5pKSzVyPUiuNVMyPzVizszN M1PITXNCVkeHUh?=
NCI-H441 MlOxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{jVVmlEPTB;OD6xPVMh|ryP NFLlR5pUSU6JRWK=
HSC-4 M1LhRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{jZSWlEPTB;OD6yPFczKM7:TR?= NVjHXXJ6W0GQR1XS
LXF-289 M4Cxcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml7jTWM2OD16LkO1PVQ{KM7:TR?= MW\TRW5ITVJ?
MRK-nu-1 NH3JN3RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlHrTWM2OD16LkO2N|A1KM7:TR?= MVXTRW5ITVJ?
no-11 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2e5XmlEPTB;OD60O|E{OyEQvF2= NGrCcHpUSU6JRWK=
SNU-387 MkPzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\XfHBKSzVyPUiuOlMzPDZizszN NEjzR5JUSU6JRWK=
Detroit562 MmDZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHS1cFJKSzVyPUiuO|U1PTVizszN MkT0V2FPT0WU
SW954 NWnJN|NsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIXYcIxKSzVyPUiuO|Y5OzJizszN M2Hv[XNCVkeHUh?=
P12-ICHIKAWA NEHUR2xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEXoWFhKSzVyPUiuO|g6PCEQvF2= MWXTRW5ITVJ?
TE-9 MoGyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYDJR|UxRThwOEGwOlIh|ryP MUnTRW5ITVJ?
NB13 NHPoZWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnTUTWM2OD16LkizO|k3KM7:TR?= NXfBOoNSW0GQR1XS
BPH-1 Mkm2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRThwOEWwPFEh|ryP NFLPRllUSU6JRWK=
KMOE-2 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mof4TWM2OD16Lki3PFkzKM7:TR?= NGPE[WxUSU6JRWK=
RPMI-8402 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYHZbHNmUUN3ME24Mlg6QTJ4IN88US=> MljnV2FPT0WU
OVCAR-3 M4DCVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2njVGlEPTB;OD65O|c{OiEQvF2= NUXBfmwzW0GQR1XS
NCI-H2196 NWfrfJFsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYHJR|UxRThwOUi2NFYh|ryP NF\JcllUSU6JRWK=
MZ7-mel NF60VoVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYPJR|UxRTlwMEO0OkDPxE1? MYjTRW5ITVJ?
GP5d M{LHUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm\ITWM2OD17LkC2N|E{KM7:TR?= MWfTRW5ITVJ?
NCI-N87 NUfnVJQ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWfGWY5iUUN3ME25MlQ1PzNzIN88US=> NYXTN|FLW0GQR1XS
EW-16 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHvSUllKSzVyPUmuOFQ5PDhizszN NGLQWGNUSU6JRWK=
Calu-6 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEnEU2xKSzVyPUmuOFk4ODNizszN MVnTRW5ITVJ?
LC4-1 MlWyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MofxTWM2OD17Lk[yOVch|ryP MWfTRW5ITVJ?
CCRF-CEM M3HOe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnnYTWM2OD17Lk[4O|Y3KM7:TR?= M3j4[XNCVkeHUh?=
BC-1 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXfJR|UxRTlwN{i5PUDPxE1? NXuzc5FDW0GQR1XS
NCI-SNU-16 NE\2[lBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIL6fHZKSzVyPUmuO|k1QTVizszN MmnlV2FPT0WU
NCI-H28 NXLkPHN1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2fpSmlEPTB;OT64OFk{OyEQvF2= MlXnV2FPT0WU
SBC-1 NInacJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2\tTmlEPTB;MUCuNFczKM7:TR?= MmmxV2FPT0WU
TUR NYThTpRqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3z1dmlEPTB;MUCuNVY2PyEQvF2= MlLrV2FPT0WU
MDA-MB-231 Mom1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYHRXXA2UUN3ME2xNE4zOTF2IN88US=> NEDlOWNUSU6JRWK=
C3A M1XDdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYLJR|UxRTFyLkOxO|kh|ryP NF;aZoVUSU6JRWK=
SW1990 NITO[mRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXK5eJlNUUN3ME2xNE4{OjhizszN NXOybnhpW0GQR1XS
NCI-H1993 M4jrfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3LuPWlEPTB;MUCuOVY6OyEQvF2= NFvN[WJUSU6JRWK=
SK-CO-1 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFnCeHpKSzVyPUGwMlc4PyEQvF2= MWrTRW5ITVJ?
OAW-28 M3XRUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTFyLkm4PFgh|ryP M{TRcnNCVkeHUh?=
HN NWHiZZRxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYrJR|UxRTFzLkGxN|Eh|ryP NH;jVYhUSU6JRWK=
NCI-H1304 NF\6cFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFfsXWdKSzVyPUGxMlE2PzZizszN M2TTPXNCVkeHUh?=
Daoy NWXiT5poT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGSwbGRKSzVyPUGxMlQ{OzZizszN M3vDPHNCVkeHUh?=
VA-ES-BJ MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFXZR4lKSzVyPUGxMlcyQTVizszN MYTTRW5ITVJ?
MCF7 Ml3oS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoTPTWM2OD1zMT64NVI3KM7:TR?= NXvL[mVlW0GQR1XS
VM-CUB-1 NFzJXFlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MULJR|UxRTFzLkmwPVEh|ryP NHS4UIRUSU6JRWK=
IPC-298 Mn3kS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVzJR|UxRTFzLkmzPFMh|ryP MYTTRW5ITVJ?
NCI-H2126 M{Lhcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHPybXNKSzVyPUGyMlAzOThizszN NF61Z49USU6JRWK=
OVCAR-8 M1n4TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXfiNIUzUUN3ME2xNk4yOTRzIN88US=> M2LHOXNCVkeHUh?=
SJRH30 M1nhVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm[2TWM2OD1zMj6yNlk6KM7:TR?= MlvsV2FPT0WU
DMS-53 MlP4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEi1Z5FKSzVyPUGyMlI3PDlizszN MmrBV2FPT0WU
NCI-H322M MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTF{LkOzOVch|ryP NU\X[VlnW0GQR1XS
RVH-421 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1jZdmlEPTB;MUKuOFkxPCEQvF2= MmfhV2FPT0WU
Raji MljhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFe5NYFKSzVyPUGyMlYyPCEQvF2= MVLTRW5ITVJ?
MDA-MB-415 M124Smdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHzvSZpKSzVyPUGyMlY1PDRizszN M2LoSnNCVkeHUh?=
EFE-184 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWDJR|UxRTF{LkexNFYh|ryP NIS1NIFUSU6JRWK=
BFTC-909 MnezS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUnJR|UxRTF{LkmyOFch|ryP NFLG[HlUSU6JRWK=
BHY MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnjjTWM2OD1zMz6zN|kh|ryP MmrQV2FPT0WU
YKG-1 NHryWJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkPKTWM2OD1zMz6zO|Q6KM7:TR?= MUTTRW5ITVJ?
EW-3 NXrKdYhST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlPaTWM2OD1zMz63NVY{KM7:TR?= MVjTRW5ITVJ?
HCC1143 NWLXb4k3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M17EZmlEPTB;MUOuO|Q{PyEQvF2= NXG3c|dRW0GQR1XS
REH MnjMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MknrTWM2OD1zMz64PVgzKM7:TR?= M4X3W3NCVkeHUh?=
CESS M2HTNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIK5TXBKSzVyPUGzMlk1QDlizszN MnzSV2FPT0WU
EFM-19 M3nCUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoqzTWM2OD1zND6xNVEzKM7:TR?= NVz0[IQ{W0GQR1XS
U031 MnvWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmnkTWM2OD1zND60NFg2KM7:TR?= NFL3dphUSU6JRWK=
ES1 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWLRNmI1UUN3ME2xOE41QDVzIN88US=> MVTTRW5ITVJ?
HSC-3 NIrBXllIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHS4clFKSzVyPUG0MlYzOTVizszN NW\me|d7W0GQR1XS
LOXIMVI NUjEVItzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjnfJBKSzVyPUG0MlcxPjhizszN NGfxVXBUSU6JRWK=
A388 NV7tRo94T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2fVZmlEPTB;MUSuO|U2PiEQvF2= MXjTRW5ITVJ?
KP-N-YS MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3vaPGlEPTB;MUSuO|c{KM7:TR?= Mof4V2FPT0WU
Capan-2 NFTOfpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXu4TmV4UUN3ME2xOE44QDZizszN MYDTRW5ITVJ?
SKG-IIIa M2Oxd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlT3TWM2OD1zND64PFYzKM7:TR?= M3jheHNCVkeHUh?=
HEL Mo\PS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXnSOmtOUUN3ME2xOE45QTl5IN88US=> NGHJOY9USU6JRWK=
BEN NG\1d|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWLJR|UxRTF2Lkm3OlYh|ryP NWm2ZYVoW0GQR1XS
MC116 M2nEPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnW4TWM2OD1zNT6xOVk6KM7:TR?= MVjTRW5ITVJ?
IGROV-1 NWDWU3RjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlTDTWM2OD1zNT6yN|E4KM7:TR?= M{XiW3NCVkeHUh?=
NCI-H1648 MkK4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXjTTXI5UUN3ME2xOU42OzB3IN88US=> NIjU[VdUSU6JRWK=
ABC-1 NHTrSIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkjXTWM2OD1zNT64NFM{KM7:TR?= MWHTRW5ITVJ?
EW-18 NYT5dnhzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoDtTWM2OD1zNT65PVc6KM7:TR?= MlX4V2FPT0WU
BC-3 NXz4TZJET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWjJR|UxRTF4LkC1OlIh|ryP MmDLV2FPT0WU
NCI-H1437 MofBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnSUlFKSzVyPUG2MlA3PjdizszN MknUV2FPT0WU
SCC-15 MlP4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NELBfFlKSzVyPUG2MlI5OjVizszN Mmi1V2FPT0WU
TT NXPnPXRLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWWzUot[UUN3ME2xOk42QDh6IN88US=> MlT1V2FPT0WU
KINGS-1 NXL4XW9PT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn7PTWM2OD1zNj64Nlc{KM7:TR?= MY\TRW5ITVJ?
C32 M{TxVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NG\2NY1KSzVyPUG2Mlk4OTdizszN NUnyXFRDW0GQR1XS
SBC-5 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVPJR|UxRTF5LkG0O|kh|ryP NIXXbolUSU6JRWK=
NB1 M{DVNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRTF5LkOxPFgh|ryP MY\TRW5ITVJ?
EB-3 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnPUTWM2OD1zNz61O|Yh|ryP NFnPVllUSU6JRWK=
NCI-H748 M1voWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIqzdHlKSzVyPUG3MlcxOzVizszN M1yxRXNCVkeHUh?=
IST-SL1 NGjiSZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MofRTWM2OD1zNz63OVI3KM7:TR?= MWPTRW5ITVJ?
WM-115 NIPrb5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1LvO2lEPTB;MUeuPFA5PSEQvF2= MkfGV2FPT0WU
NCI-H226 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnrGTWM2OD1zNz65OVQ3KM7:TR?= NFLyUllUSU6JRWK=
CAL-33 M1vz[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEXrNYlKSzVyPUG4MlI4QDFizszN MmPXV2FPT0WU
SCC-4 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml[5TWM2OD1zOD6zNlI6KM7:TR?= MlruV2FPT0WU
RMG-I MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV3Jc5R{UUN3ME2xPE43QTR5IN88US=> M3TNWnNCVkeHUh?=
KOSC-2 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTF6Lke3OFYh|ryP M3z0ZnNCVkeHUh?=
A2058 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHsUm1LUUN3ME2xPE45OjV3IN88US=> Mn;rV2FPT0WU
HCC70 MnyyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1TuNWlEPTB;MUmuN|g6PCEQvF2= NXT4OJl4W0GQR1XS
C2BBe1 NWjMNohsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmXoTWM2OD1zOT60NVQ5KM7:TR?= NYH3c4tZW0GQR1XS
NCI-H650 NWnSXY1RT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUPxfpZ[UUN3ME2xPU42QDl7IN88US=> NWrPXHhnW0GQR1XS
CAL-72 NFjMVZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXjR[|ZUUUN3ME2xPU43PzN5IN88US=> MlnKV2FPT0WU
L-363 M3;Gd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlXFTWM2OD1{MD6wNlEzKM7:TR?= NXW0d4RLW0GQR1XS
SNU-423 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYnJR|UxRTJyLkGwOFMh|ryP NVHkUnBvW0GQR1XS
PLC-PRF-5 M3zafmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV3JR|UxRTJyLkO5NFYh|ryP NILaclBUSU6JRWK=
SW1463 MnO1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVPmb4w2UUN3ME2yNE41PTJ3IN88US=> NE\4fHFUSU6JRWK=
769-P Mkm2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFHoTHdKSzVyPUKwMlY4PjlizszN NFyyNoVUSU6JRWK=
DMS-79 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NY\SNohQUUN3ME2yNE45PDlizszN NWPzXphIW0GQR1XS
Saos-2 MkS4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoLhTWM2OD1{MD65OVU3KM7:TR?= MY\TRW5ITVJ?
CHP-126 MlzrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NInG[49KSzVyPUKxMlQ1PjJizszN NWTJcoFqW0GQR1XS
SW837 M{XS[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHLjTZpKSzVyPUKxMlQ6OzlizszN M3PEZXNCVkeHUh?=
SHP-77 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHLF[pBKSzVyPUKxMlYyOjJizszN MXjTRW5ITVJ?
DB MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGTMXXRKSzVyPUKxMlYyPDJizszN Moi2V2FPT0WU
ES5 MkC0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NI[z[lRKSzVyPUKxMlY5PjRizszN NFy1eIpUSU6JRWK=
COR-L23 MlfoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWLJR|UxRTJzLkiwOVEh|ryP NVO2ZVZGW0GQR1XS
KU-19-19 NWLwXWJpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYPJR|UxRTJzLki5PFIh|ryP MYPTRW5ITVJ?
T84 NHvKWm9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1yxeGlEPTB;MkGuPVgyQSEQvF2= MkXIV2FPT0WU
NCI-H630 NEHYbnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFTGW3ZKSzVyPUKyMlU{PjNizszN M3;t[nNCVkeHUh?=
LU-165 M{frbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHTBSWVKSzVyPUKyMlU2PCEQvF2= M1\xUHNCVkeHUh?=
COLO-792 NEXVcI5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnLmTWM2OD1{Mj63NVEyKM7:TR?= NUHWeo9ZW0GQR1XS
CAL-62 M1nVPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4jyNGlEPTB;MkKuO|UyPyEQvF2= NWfifplIW0GQR1XS
HCE-T Mkj1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NG\IU3NKSzVyPUKyMlg3ODZizszN NHzxcHFUSU6JRWK=
BB65-RCC M4TZSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTJ|LkCzOFQh|ryP MWLTRW5ITVJ?
SiHa M3j6TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGjLVVFKSzVyPUKzMlM6PjhizszN NVHye2prW0GQR1XS
NCI-H2081 NFT2b2pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{PEcGlEPTB;MkSuNFY1OSEQvF2= M2rBdHNCVkeHUh?=
U251 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmDSTWM2OD1{ND6wOlY5KM7:TR?= M4XyNnNCVkeHUh?=
LoVo MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWrJR|UxRTJ2LkmyPFIh|ryP M4TiNHNCVkeHUh?=
GCIY NGHPNJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX3HNVZvUUN3ME2yOU4zQDd5IN88US=> MV7TRW5ITVJ?
NUGC-3 NYPHXnY{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmfQTWM2OD1{NT6zN|E3KM7:TR?= MmDxV2FPT0WU
LNCaP-Clone-FGC MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFLOc45KSzVyPUK1MlM1QThizszN M3flS3NCVkeHUh?=
PA-1 NVjaemxnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{n5NmlEPTB;MkWuOlg{OyEQvF2= MV3TRW5ITVJ?
OE33 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M37mfGlEPTB;MkWuOlg2OyEQvF2= MUjTRW5ITVJ?
HT-29 M4rQ[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFXyTVdKSzVyPUK1Mlc5PzlizszN MV3TRW5ITVJ?
RCM-1 NIHY[4dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmX3TWM2OD1{NT65OlU3KM7:TR?= M4Hx[nNCVkeHUh?=
NCI-H1522 NYLjN41CT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkHXTWM2OD1{NT65PVEyKM7:TR?= MlrmV2FPT0WU
LB373-MEL-D MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIXR[ZpKSzVyPUK2MlE4ODhizszN NXLvfFVYW0GQR1XS
NCI-H1436 NF2zSW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXPWR5NvUUN3ME2yOk4zPzN6IN88US=> Mlf5V2FPT0WU
COLO-824 NETTNGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3ZVVVtUUN3ME2yOk41ODB{IN88US=> MnzZV2FPT0WU
CP50-MEL-B MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYPJR|UxRTJ4LkW2O|Uh|ryP M1naS3NCVkeHUh?=
EGI-1 NXrvRYw5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M13QOGlEPTB;MkeuNlY6QCEQvF2= NVvzcGFZW0GQR1XS
LAN-6 Mn\CS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWPu[VVbUUN3ME2yO{4{PTl6IN88US=> MmHoV2FPT0WU
GAK NFTUTnZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkXRTWM2OD1{Nz60NlI2KM7:TR?= Mo\DV2FPT0WU
MDA-MB-175-VII MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV7JR|UxRTJ5LkWwOVMh|ryP NVLpVWFQW0GQR1XS
JVM-2 NInSVmpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlHjTWM2OD1{Nz62OlIzKM7:TR?= NVHjZlFUW0GQR1XS
UACC-257 Mk\1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWnJR|UxRTJ5Lk[4O|gh|ryP MVvTRW5ITVJ?
SW1783 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NE\zdlBKSzVyPUK3Mlc4QDNizszN Ml:zV2FPT0WU
HT-3 NYX4W|YzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYq5XmxDUUN3ME2yPE4zOTZ4IN88US=> MmrJV2FPT0WU
RL NIrPOVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHyyNpVKSzVyPUK4MlU6OTFizszN MXTTRW5ITVJ?
TK10 MljDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NE\2ZWNKSzVyPUK4MlY2OzVizszN MmrIV2FPT0WU
HT55 NVrvUGJ2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXTrTYl2UUN3ME2yPU4xPTZ3IN88US=> NGW4T5NUSU6JRWK=
BT-20 M3zNOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3n6Z2lEPTB;MkmuNFU5PiEQvF2= MX\TRW5ITVJ?
TGBC24TKB MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmP5TWM2OD1{OT6xPFMyKM7:TR?= MoX1V2FPT0WU
HSC-2 MljvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYPJR|UxRTJ7LkOwNFEh|ryP MVrTRW5ITVJ?
COLO-205 M4ntdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXrJR|UxRTJ7LkO5OFQh|ryP NV\6U2hUW0GQR1XS
GT3TKB M1;Cemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{TtXGlEPTB;MkmuOlg4PyEQvF2= M1ezT3NCVkeHUh?=
T47D NVjCVYxRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{jZ[mlEPTB;MkmuPFU5OiEQvF2= NXrVc3NSW0GQR1XS
OMC-1 M{TpUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlPPTWM2OD1|MD6xPVE6KM7:TR?= M{naSnNCVkeHUh?=
PFSK-1 NX7XVolYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkW3TWM2OD1|MT6yOlU6KM7:TR?= NIXkSJVUSU6JRWK=
JEG-3 M4nPdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF[4V4dKSzVyPUOxMlM2PjFizszN NYTIWoRoW0GQR1XS
RD MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYnId|YyUUN3ME2zNU42OTF3IN88US=> MW\TRW5ITVJ?
NCI-H64 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXfmXZFLUUN3ME2zNk41OTd7IN88US=> MYLTRW5ITVJ?
DMS-114 MlvIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGfkd4lKSzVyPUOyMlQyQDJizszN MmHtV2FPT0WU
NCI-H661 M2\zcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTN{Lk[1NFEh|ryP M1\kOHNCVkeHUh?=
CAL-148 M1TONmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NITXTo1KSzVyPUOyMlY3PjVizszN Mnu3V2FPT0WU
HuP-T3 NFrVc|JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFO0SHpKSzVyPUOyMlk{OzhizszN NFKxUnNUSU6JRWK=
ES4 M4nOeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXfJR|UxRTN|LkG3NFUh|ryP NIL4OpJUSU6JRWK=
Ca9-22 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIK2SG5KSzVyPUOzMlQ3ODFizszN NVP1W5dJW0GQR1XS
LP-1 NYTzUGdST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHfaZlBKSzVyPUO0MlA6KM7:TR?= NIXDcWZUSU6JRWK=
AU565 M{OwPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHPUR3FKSzVyPUO0MlUxPjlizszN MnuyV2FPT0WU
MDA-MB-453 M3zvPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml;WTWM2OD1|NT6xOFI3KM7:TR?= NXfh[WNkW0GQR1XS
SNU-C1 Mo[xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkjvTWM2OD1|NT6xO|Eh|ryP MWPTRW5ITVJ?
SW13 NFz2em1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2PQVmlEPTB;M{WuOFA4PiEQvF2= MWDTRW5ITVJ?
NCI-H2122 MmLWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MofyTWM2OD1|NT61OVk5KM7:TR?= M3n5dnNCVkeHUh?=
NCI-H1395 NX7Le2UxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYCxOldDUUN3ME2zOU43PjlzIN88US=> NGLUZWVUSU6JRWK=
J-RT3-T3-5 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXmyblJzUUN3ME2zOk4xOjl2IN88US=> NFXEcplUSU6JRWK=
COR-L279 MlHLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWXJR|UxRTN4LkG5PFEh|ryP NEL1cY9USU6JRWK=
ATN-1 NEXHSWFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NILobWZKSzVyPUO2Mlg2OTZizszN NVjvUmRDW0GQR1XS
HCC2998 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkPzTWM2OD1|Nj64OVcyKM7:TR?= NWHuVWR{W0GQR1XS
UM-UC-3 NF\leGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYPjOFczUUN3ME2zOk45Pjd3IN88US=> NXjaZVY2W0GQR1XS
DV-90 NEjibIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVi2ZYNvUUN3ME2zOk46ODZ5IN88US=> M4X2WnNCVkeHUh?=
ES8 M4jWPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4Xxd2lEPTB;M{[uPVMyQCEQvF2= NEPVeHFUSU6JRWK=
YAPC M2DYOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1HIU2lEPTB;M{[uPVY2PCEQvF2= MV\TRW5ITVJ?
HCC1599 NGXjUZFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVzw[4JnUUN3ME2zO{4yPjF6IN88US=> NGTFNIlUSU6JRWK=
UMC-11 Mn63S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWrBUZoyUUN3ME2zO{4zPTB|IN88US=> NG\vWplUSU6JRWK=
THP-1 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHO4W4RKSzVyPUO3MlI5PjhizszN NUj0WWxnW0GQR1XS
OCUB-M NX\HSGw5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUDZfpVKUUN3ME2zO{4zQDlzIN88US=> M{LFRnNCVkeHUh?=
NCI-H1693 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGrqW5pKSzVyPUO3MlMzOzNizszN MoXqV2FPT0WU
NCI-H345 NF\ufYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUDJR|UxRTN5LkO2NlQh|ryP NH\tbXdUSU6JRWK=
COLO-800 M1z1S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MW\JR|UxRTN5LkW2O{DPxE1? MVrTRW5ITVJ?
COLO-320-HSR Mn;kS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NU[y[2FwUUN3ME2zPE4{PDl{IN88US=> M3;ubXNCVkeHUh?=
NCI-H596 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHJTWM2OD1|OD60OFg6KM7:TR?= NYC5[|FHW0GQR1XS
NCI-H187 M1[1NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2S4UGlEPTB;M{iuO|M1PCEQvF2= NVLXN2h3W0GQR1XS
ECC4 M2WwbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXPCeGZwUUN3ME2zPU4xQDF2IN88US=> MVXTRW5ITVJ?
KP-4 M3jadGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnPiTWM2OD1|OT6xNlM2KM7:TR?= MlzjV2FPT0WU
NCI-H2227 M{LCRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIXXNVVKSzVyPUO5MlM6PDlizszN Mn3MV2FPT0WU
22RV1 NIXxPVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlWzTWM2OD1|OT64N|k5KM7:TR?= MWPTRW5ITVJ?
SAS M2G2ZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{n4TWlEPTB;NECuNFk3KM7:TR?= NHzhTVZUSU6JRWK=
PANC-10-05 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHv0UI9KSzVyPUSwMlE5OjhizszN NYDyeolTW0GQR1XS
MDA-MB-468 NH;PPZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGixXZlKSzVyPUSwMlU{PDZizszN Ml\5V2FPT0WU
RPMI-7951 NWDBbpZMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVnYWGFWUUN3ME20NU4zODd3IN88US=> MUXTRW5ITVJ?
BB49-HNC NWfsd|d[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2LPTWlEPTB;NEGuNlE4QSEQvF2= MWrTRW5ITVJ?
23132-87 M3LTS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYDJR|UxRTRzLkK3N|Ih|ryP M1fL[nNCVkeHUh?=
HCC1569 NX61SJJVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVj1[5k4UUN3ME20NU4zQDh3IN88US=> NIrxUphUSU6JRWK=
CP66-MEL Mk\US5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MorOTWM2OD12Mj6xPFg3KM7:TR?= NGnYXlRUSU6JRWK=
K-562 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlzJTWM2OD12Mj6yPFU1KM7:TR?= NW\iWmZtW0GQR1XS
OCI-AML2 NWrLNIFWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmXlTWM2OD12Mj64PVc1KM7:TR?= MlPHV2FPT0WU
SW756 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4myV2lEPTB;NEOuNFM5QCEQvF2= NXHFXHo5W0GQR1XS
M14 NWn1[IJXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYH6OnVFUUN3ME20N{4{OTh7IN88US=> MlLXV2FPT0WU
NCI-H1623 M{j4TWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXGye41WUUN3ME20N{41PjRizszN NGC5SXNUSU6JRWK=
KNS-81-FD NXq2eJk4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF3ldFZKSzVyPUSzMlc3OiEQvF2= MUDTRW5ITVJ?
TGBC1TKB M3XDdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MljaTWM2OD12Mz65NFk6KM7:TR?= MYnTRW5ITVJ?
RERF-LC-MS NYrxSXByT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MofFTWM2OD12Mz65NlgyKM7:TR?= NX75XopIW0GQR1XS
PC-3 NEH1V5NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXPJR|UxRTR2LkSzOFch|ryP NHfqb49USU6JRWK=
HuP-T4 NV\4PZVtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYDJR|UxRTR2LkS0O|Qh|ryP Ml3MV2FPT0WU
NCI-H510A NIriWVJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MofvTWM2OD12ND63NFgh|ryP NELYb2tUSU6JRWK=
LB2518-MEL MoXNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXvnNnhLUUN3ME20OE44QTN5IN88US=> MlLJV2FPT0WU
TE-5 M4r4O2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVu3ZodmUUN3ME20OU46PThzIN88US=> M2SzNnNCVkeHUh?=
EW-24 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NE\WVYRKSzVyPUS2MlE4OjNizszN NF\pb25USU6JRWK=
LB647-SCLC NV2ySJAyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmfFTWM2OD12Nj6yNVU2KM7:TR?= M13jV3NCVkeHUh?=
NCI-H524 NED5S45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWLscI5iUUN3ME20Ok44OTh3IN88US=> M{\KbXNCVkeHUh?=
EW-11 MkjKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXHJR|UxRTR4LkmzO|Mh|ryP NID2fGVUSU6JRWK=
KALS-1 M{G0e2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV3BXWxrUUN3ME20O{4zODZ4IN88US=> MnvtV2FPT0WU
BT-474 MoTsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUezN5BwUUN3ME20O{41OjF4IN88US=> MkHsV2FPT0WU
SK-N-AS M{TRUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRTR5Lki4PEDPxE1? MXnTRW5ITVJ?
HCC2157 NGPxbZZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVHJR|UxRTR6LkC3OkDPxE1? NE\3eWxUSU6JRWK=
HCC1954 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV3GOZgzUUN3ME20PE4yPzB2IN88US=> NH2zcYFUSU6JRWK=
FADU M3H1Zmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVTJR|UxRTR6LkOwN|Eh|ryP M4CyS3NCVkeHUh?=
S-117 Mn7sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWfJR|UxRTR6LkO4NVUh|ryP M3PodHNCVkeHUh?=
LS-1034 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUHhN5B1UUN3ME20PE44ODZ5IN88US=> MVzTRW5ITVJ?
CAMA-1 NX;uNGI{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXG1Oph7UUN3ME20PU42PTR|IN88US=> NVHJXIw2W0GQR1XS
LU-134-A Mo\FS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUnPOolFUUN3ME20PU45ODh3IN88US=> M2X6cXNCVkeHUh?=
NCI-H1838 MnWzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MU\JR|UxRTR7LkiwPFch|ryP NHW4OnJUSU6JRWK=

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
pSrc / Src / pPlcg / Plcg / pStat5 / Stat5 ; 

PubMed: 22781593     


In (B) inhibition of Src, Plcg and Stat5 was seen in MLNAF cell lines treated with Ponatinib; ZNF112 expresses ZMYM2–FGFR1, CEP2A and CEP5A cells express CEP110–FGFR1 and BBC2 expresses BCR–FGFR1.

pFGFR1(pY20) / FGFR1; 

PubMed: 22781593     


Western blot analysis, using various antibodies specific for downstream targets of FGFR1, demonstrates that Ponatinib inhibits the activation of Plcg and Src as a result of inhibiting the FGFR1 fusion kinase in human KG1 cells. 

cleaved caspase-3 / cleaved caspase-7 / BAX / Bcl-2; 

PubMed: 30959969     


Western blot analysis of cleaved caspase-3, cleaved caspase-7, Bax, Bcl-2, and β-Tubulin (control) in treated cells.

p-Rb(S807/811) / Rb / CDK4 / CDK6 / Cyclin D1 / CDK2 / Cyclin E1; 

PubMed: 30959969     


Western blot analysis of Rb/p-Rb, CDK4, CDK6, Cyclin D1, CDK2, Cyclin E1, and β-Tubulin (control) in the SK-Hep-1 and SNU-423 cells treated with ponatinib. 

RAD51; 

PubMed: 30959969     


The effect of ponatinib on the concentration of Rad51 in SK-Hep-1 and SNU-423 cells.

p-MEK / MEK / p-ERK / ERK; 

PubMed: 30959969     


Effect of ponatinib on the phosphorylation of Mek and Erk. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was used as a control.

c-Jun / p-JNK(T183/Y185) / JNK; 

PubMed: 30959969     


Effect of ponatinib on the phosphorylation of JNK and c-Jun. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was used as a control.

p-p38 MAPK / p38 MAPK; 

PubMed: 30959969     


Effect of ponatinib on the phosphorylation of p38. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was used as a control.

p-JAK2 / JAK2 / p-STAT3 / STAT3; 

PubMed: 30959969     


Effect of ponatinib on the phosphorylation of Jak2, and Stat3. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was used as a control.

PI3K p85 / p-PI3K / p-PDK1 / PDK1 / p-mTOR / mTOR; 

PubMed: 30959969     


Effects of ponatinib on the protein concentration and phosphorylation of PI 3-kinase, PDK1, Akt, and mTOR in HCC cells. 

p-PDGFRα / PDGFRα; 

PubMed: 24472312     


Ponatinib inhibited phosphorylation of PDGFRα in a concentration-dependent manner. EOL-1 and BaF3-WT or -T674I FIP1L1-PDGFRα cells were exposed to escalating concentrations of ponatinib for 24 h.

PARP / Caspase-3 / Active Caspase-3; 

PubMed: 24472312     


The concentration- (for 24 h) and time-dependent (1 nM for EOL-1, 300 nM for BaF3-WT and -T674I FIP1L1-PDGFRα cells) cleavage of PARP and caspase-3 triggered by ponatinib was analyzed by immunoblotting.

AIF / Cyto C ; 

PubMed: 24472312     


Ponatinib elicited release of AIF and cytochrome c into the cytosol. Cells were treated with 1 nM ponatinib for the indicated durations and the cytosolic fraction was extracted with digitonin buffer. Levels of AIF and Cytochrome c (Cyto c) were detected by immunoblotting.

Mcl-1 / Survivin / Bcl-Xl / XIAP / Bax / Bcl-2 / Bim; 

PubMed: 24472312     


Immunoblotting of apoptosis-related proteins in CEL cells after treatment for 24 h.

β-catenin ; 

PubMed: 24472312     


Ponatinib concentration-dependently lowered β-catenin. EOL-1 cells were incubated with ponatinib for 24 h, and cytoplasmic and nuclear extracts were determined by immunoblotting.

β-catenin; 

PubMed: 24472312     


Analysis of β-catenin localization. EOL-1 cells were pretreated with 1 nM ponatinib for 24 h, immunofluorescence analysis was performed with anti-β-catenin. Nuclei were stained with 4,6-diamidino-2-phenylindole (DAPI). 

ABL; 

PubMed: 19878872     


In vitro [γ-32P]-ATP autophosphorylation of full-length (A) ABL or (B) ABLT315I kinase treated with AP24534, imatinib, nilotinib, or dasatinib. After incubation of tyrosine-dephosphorylated enzyme with the indicated inhibitor in the presence of [γ-32P]-ATP and separation by SDS-PAGE, signal intensity was measured by autoradiography.

22781593 30959969 24472312 19878872
Growth inhibition assay
Cell viability; 

PubMed: 30174789     


(A) Effect of Ponatinib on basal viability of HUVECs. The cells were treated with Ponatinib at indicated concentrations or 0.1% DMSO (vehicle control) for 24 h.

30174789
In vivo In a mouse xenograft model of Ba/F3 cells expressing native Bcr-Abl, AP24534 (2.5 mg/kg and 5 mg/kg) prolongs mice median survival. In the xenograft model of Ba/F3 Bcr-AblT315I, AP24534 (10 mg/kg–50 mg/kg) significantly suppresses tumor growth. AP24534 (30 mg/kg) decreases the phosphorylated Bcr-Abl and phosphorylated CrkL levels in the tumors. [2]

Protocol

Kinase Assay:[1]
- Collapse

Peptide substrate phosphorylation assays with GST-Abl kinase domains:

The effect of AP24534 (0-320 nM) on GST-Abl kinase activity is assessed by using a synthetic peptide substrate (Abltide: EAIYAAPFAKKK). Assays are carried out at 30 °C for 15 min in 25 μL reaction mixture: 8 mM MOPS (pH 7), 0.2 mM EDTA, 50 μM Abltide, 30 mM MgCl2, 10 mM β-glycerol phosphate, 1 mM EGTA, 0.002% Brij-35, 0.4 mM DTT, 0.2 mg/mL BSA, 0.4 mM sodium orthovanadate, 10 nM WT or mutant GST-Abl kinase, and 100 µM ATP/γ-32[P]ATP (5000 cpm/pmol). Reactions are terminated by transferring a portion of the reaction mixture onto a p81 phosphocellulose filter and immersing in 0.75% phosphoric acid. Filters are washed 3 times in 0.75% phosphoric acid, rinsed in acetone, and air dried; phosphate incorporation is determined by scintillation counting. All results are corrected for background binding to the filters, as determined by omitting peptide substrate from the kinase reaction. Time course experiments to establish the linear range of enzymatic activity precedes kinase assays.
Cell Research:[2]
- Collapse
  • Cell lines: Ba/F3 cells expressing Bcr-Abl or a range of single mutations in the kinase domain of Bcr-Abl
  • Concentrations: 0-625 nM
  • Incubation Time: 72 hours
  • Method: Ba/F3 cell lines are distributed in 96-well plates (4 × 103 cells/well) and incubated with AP24534 for 72 hours. Proliferation is measured using a methanethiosulfonate (MTS)-based viability assay (CellTiter96 Aqueous One Solution). All values are normalized to the control wells with no drug. IC50 values are reported as the mean of three independent experiments performed in quadruplicat
    (Only for Reference)
Animal Research:[1]
- Collapse
  • Animal Models: Mouse xenograft models of Ba/F3 cells expressing Bcr-Abl or Bcr-AblT315I
  • Dosages: 2.5 mg/kg and 5 mg/kg for Ba/F3 Bcr-Abl; 2.5 mg/kg–50 mg/kg for Ba/F3 Bcr-AblT315I
  • Administration: Oral gavage once daily
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 30 mg/mL (56.33 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
1% CMC Na
For best results, use promptly after mixing.
30mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 532.56
Formula

C29H27F3N6O

CAS No. 943319-70-8
Storage powder
in solvent
Synonyms N/A
Smiles CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04160546 Recruiting Drug: Ponatinib 15 MG|Drug: Acetylsalicylic acid 100 MG Chronic Myeloid Leukemia Chronic Phase Fundacion CRIS de Investigación para Vencer el Cáncer|Incyte Biosciences UK|Apices Soluciones S.L. January 17 2020 Phase 2
NCT04070443 Recruiting Drug: Ponatinib|Drug: Imatinib Philadelphia Chromosome Positive CML|BCR-ABL Positive Chronic Myelogenous Leukemia Centre Leon Berard November 13 2019 Phase 2
NCT03934372 Recruiting Drug: Ponatinib Acute Myeloid Leukemia|Accelerated Phase Chronic Myeloid Leukemia|Blast Phase Chronic Myeloid Leukemia|Chronic Phase Chronic Myeloid Leukemia|Acute Lymphoblastic Leukemia|Acute Lymphocytic Leukemia|Leukemia|Lymphoma|Solid Tumors Incyte Biosciences International Sàrl|Incyte Corporation November 22 2019 Phase 1|Phase 2
NCT03895671 Recruiting Drug: Ponatinib|Drug: Azacitidine CHRONIC MYELOGENOUS LEUKAEMIA IN ACCELERATED PHASE|CHRONIC MYELOGENOUS LEUKAEMIA IN MYELOID BLAST CRISIS Versailles Hospital June 19 2019 Phase 2
NCT03690115 Recruiting Drug: Ponatinib 30 MG Leukemia Myeloid Acute Versailles Hospital December 12 2018 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    Is the pre-solubilized inhibitor suitable for in vivo whole animal studies? Whether the solvent contains any non-DMSO stabilizer?

  • Answer:

    Our 10mM Ponatinib in DMSO solution is in pure DMSO and there is not other stabilizer added. You can use it for animal study. The vehicle we suggest for Ponatinib is: 30% PEG400/0.5% Tween80/5% Propylene glycol. It is a milky suspension used for oral gavage.

Bcr-Abl Signaling Pathway Map

Bcr-Abl Inhibitors with Unique Features

Related Bcr-Abl Products

Tags: buy Ponatinib (AP24534) | Ponatinib (AP24534) supplier | purchase Ponatinib (AP24534) | Ponatinib (AP24534) cost | Ponatinib (AP24534) manufacturer | order Ponatinib (AP24534) | Ponatinib (AP24534) distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID