Ponatinib (AP24534)

Catalog No.S1490

Ponatinib (AP24534) Chemical Structure

Molecular Weight(MW): 532.56

Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively.

Size Price Stock Quantity  
In DMSO USD 100 In stock
USD 110 In stock
USD 370 In stock
USD 970 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Cited by 83 Publications

Purity & Quality Control

Choose Selective Bcr-Abl Inhibitors

Biological Activity

Description Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively.
Targets
Abl [1]
(Cell-free assay)
PDGFRα [1]
(Cell-free assay)
VEGFR2 [1]
(Cell-free assay)
FGFR1 [1]
(Cell-free assay)
c-Src [1]
(Cell-free assay)
0.37 nM 1.1 nM 1.5 nM 2.2 nM 5.4 nM
In vitro

AP24534 potently inhibits native Abl, AblT315I, and other clinically important Abl kinase domain mutants with IC50 of 0.30 nM–2 nM. AP24534 doesn't inhibit Aurora kinase family members, nor does it inhibit insulin receptor or CDK2/cyclin E. AP24534 inhibits proliferation of Ba/F3 cells expressing Bcr-Abl with IC50 of 0.5 nM, as well as Ba/F3 cells expressing a range of Bcr-Abl mutants with IC50 of 0.5 nM–36 nM. The inhibition of proliferation by AP24534 is correlated with induction of apoptosis. [1-2] In leukemic cell lines containing activated forms of FLT3, KIT, FGFR1, and PDGFRα receptors, AP24534 potently inhibits receptor phosphorylation and cellular proliferation with IC50 of 0.3 nM to 20 nM. In MV4-11 (FLT3-ITD(+/+)) but not RS4;11 (FLT3-ITD(–/–)) AML cells, AP24534 inhibits FLT3 signaling and induced apoptosis at less than 10 nM. AP24534 inhibits viability of primary leukemic blasts from a FLT3-ITD positive AML patient with IC50 of 4 nM but not those from patients with AML expressing native FLT3. [3] In Ba/F3 cells engineered to express activated FGFR1-4, AP24534 potently inhibits FGFR-mediated signaling and viability with IC50 lower than 40 nM. In cell lines representing multiple tumor types (endometrial, bladder, gastric, breast, lung, and colon), and containing FGFRs dysregulated by a variety of mechanisms, AP24534 inhibits FGFR-mediated signaling with IC50 less than 40 nM and inhibits cell growth with IC50 of 7 nM–181 nM. [4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
EoL-1-cell NHTrNnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVPpcnlkUUN3ME2wMlAxODByMECzOVkh|ryP MYHTRW5ITVJ?
MV-4-11 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml7YTWM2OD1yLkCwNFA6PTZizszN M2r1UXNCVkeHUh?=
MEG-01 NHW0SWVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlKwTWM2OD1yLkCwNFEzQCEQvF2= NHGyWmRUSU6JRWK=
LAMA-84 M2jtcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEDDPXVKSzVyPUCuNFAxOTZ3IN88US=> M2foUnNCVkeHUh?=
CGTH-W-1 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFjyXWlKSzVyPUCuNFAyPjlizszN MXzTRW5ITVJ?
KASUMI-1 NEnCdZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnfOTWM2OD1yLkCwNlE4KM7:TR?= Ml;uV2FPT0WU
BE-13 MnWxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXHJR|UxRTBwMECyOVkh|ryP MlnrV2FPT0WU
CTV-1 NFrKO4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1TWdWlEPTB;MD6wNFUzOSEQvF2= NWDObmtJW0GQR1XS
NKM-1 MnHBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mni0TWM2OD1yLkCwOlU2KM7:TR?= NI\Cb5FUSU6JRWK=
MONO-MAC-6 NVr4dGppT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjnWVBKSzVyPUCuNFA5OzdizszN MVHTRW5ITVJ?
A204 MmH1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGX6N|RKSzVyPUCuNFEzOThizszN MY\TRW5ITVJ?
GDM-1 M1nFXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1TCZmlEPTB;MD6wNVg{OyEQvF2= NEXrZXpUSU6JRWK=
AN3-CA MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFvGT2JKSzVyPUCuNFE5PzNizszN MkXaV2FPT0WU
BL-70 Ml[xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVzJR|UxRTBwMEKxPVkh|ryP NXPCdoFDW0GQR1XS
Daudi Ml\wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnuSGtKSzVyPUCuNFI2OzdizszN NU\JNJZJW0GQR1XS
KU812 NIT6N3ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTBwMEK4OFgh|ryP NX3lXmlDW0GQR1XS
KG-1 NWPzS4o4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYjzRVdsUUN3ME2wMlA{Ojl2IN88US=> NGnLSW9USU6JRWK=
DOHH-2 NF3C[XNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{fKe2lEPTB;MD6wOFgxOyEQvF2= M2jnWHNCVkeHUh?=
HuO9 MnzLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFHTZ3JKSzVyPUCuNFU1PDhizszN NY\1PFRpW0GQR1XS
EB2 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWrvbYw1UUN3ME2wMlA2PTd4IN88US=> M{[4SHNCVkeHUh?=
G-402 M{Szbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHvoVWFKSzVyPUCuNFY{PDFizszN NVXCcmczW0GQR1XS
SU-DHL-1 NECxfFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3fqbWlEPTB;MD6wOlM4QSEQvF2= M3jhV3NCVkeHUh?=
NCI-H719 MoXsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUi3OpJZUUN3ME2wMlA4QDh6IN88US=> NEHVOIZUSU6JRWK=
MLMA MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYTJR|UxRTBwMEmwOkDPxE1? NYmyXnI5W0GQR1XS
KM12 MmjjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NU\LW5N5UUN3ME2wMlA6PzN5IN88US=> Mn\YV2FPT0WU
SUP-T1 M{HvTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{H4cWlEPTB;MD6wPVk5OiEQvF2= NUfBNVRIW0GQR1XS
MZ1-PC NXGwN2tmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUDnSIlVUUN3ME2wMlEyOzN4IN88US=> MXzTRW5ITVJ?
MFE-296 M2LwR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHL2eXZKSzVyPUCuNVE5OzlizszN M{D4UHNCVkeHUh?=
ALL-PO M3L6bWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4riXWlEPTB;MD6xNlQ1OyEQvF2= M13IUHNCVkeHUh?=
GB-1 NV[3UHJxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXTJR|UxRTBwMUK1NVIh|ryP Ml7KV2FPT0WU
SIG-M5 NWjQSVMzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYHnPYxkUUN3ME2wMlE{OzdizszN M1y3bnNCVkeHUh?=
P30-OHK M1TEd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTBwMUW2O|Ih|ryP NGflbFlUSU6JRWK=
NCI-H716 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MljZTWM2OD1yLkG2NlY3KM7:TR?= MlTXV2FPT0WU
MPP-89 M1HrSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MluxTWM2OD1yLkG2PVM{KM7:TR?= NWnPSHNXW0GQR1XS
SF126 NUC4V4N4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTBwMUewOlMh|ryP NWjxbFJHW0GQR1XS
CTB-1 NFPOZ|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGi1OVdKSzVyPUCuNVc{OTZizszN Mm\tV2FPT0WU
CA46 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYXjVHdLUUN3ME2wMlE4PDh7IN88US=> NYLrU3U{W0GQR1XS
NCI-H520 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUWxV5A2UUN3ME2wMlE4PzN{IN88US=> MWTTRW5ITVJ?
CAL-85-1 NFf4c|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIT6NIFKSzVyPUCuNVc6OjdizszN NUfiSo97W0GQR1XS
NCI-H2342 NFSxVWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NI\SZ3lKSzVyPUCuNVg2PzdizszN NHj5VHVUSU6JRWK=
697 M3:xV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIDLcJNKSzVyPUCuNVg5PzFizszN NYfyd|JxW0GQR1XS
NY MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXHQenkzUUN3ME2wMlE6Ojh5IN88US=> M2H0O3NCVkeHUh?=
T98G NHSwPJBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXvJR|UxRTBwMUmzNVgh|ryP Mo\HV2FPT0WU
NCI-H1703 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnTVTWM2OD1yLkG5OlE2KM7:TR?= MXnTRW5ITVJ?
NCI-H2087 NIfxSYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2nvO2lEPTB;MD6yNFQ{QSEQvF2= NYHBdHNQW0GQR1XS
PF-382 M{nzTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTBwMkC4O|Mh|ryP M1vNUnNCVkeHUh?=
HCT-116 MonmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxRTBwMkGwOlkh|ryP NYjaWYtmW0GQR1XS
CAKI-1 M173OGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnvTHFZUUN3ME2wMlIyPjZ4IN88US=> MXnTRW5ITVJ?
CCF-STTG1 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mk\ITWM2OD1yLkKyOFc2KM7:TR?= MnzNV2FPT0WU
D-392MG NYT2WVVMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX[2[pV7UUN3ME2wMlI{OTd5IN88US=> NHTROnFUSU6JRWK=
RT-112 NI\LUWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mlv2TWM2OD1yLkKzO|k2KM7:TR?= NG[xW4FUSU6JRWK=
MES-SA MkPhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1vJeGlEPTB;MD6yOFE5PyEQvF2= Ml7WV2FPT0WU
LC-2-ad NYjuT|FpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGH5TWNKSzVyPUCuNlQzPjVizszN NFvwUlRUSU6JRWK=
NOS-1 MlfBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4\NPGlEPTB;MD6yOFM3PyEQvF2= M1HaZnNCVkeHUh?=
NALM-6 M1v3Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRTBwMkW1OFMh|ryP MnLXV2FPT0WU
TE-15 Mne2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\5TWM2OD1yLkK2NFkyKM7:TR?= M4DtXXNCVkeHUh?=
786-0 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVrJbYk5UUN3ME2wMlI3OjJ6IN88US=> MV3TRW5ITVJ?
IST-MES1 NIjhT|lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEDnSXNKSzVyPUCuNlY5OjlizszN MW\TRW5ITVJ?
KYSE-180 M3nPb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUXUdJpuUUN3ME2wMlI3QDlzIN88US=> NVPMc45QW0GQR1XS
YT NGL3NHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnHMTWM2OD1yLkK2PVc1KM7:TR?= MlfRV2FPT0WU
A427 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFHCUHFKSzVyPUCuNlczPjRizszN MmizV2FPT0WU
KYSE-450 M33vfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX;JR|UxRTBwMkezNlkh|ryP NYjl[ZV7W0GQR1XS
HuH-7 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4jIWGlEPTB;MD6yO|c3OyEQvF2= NWK5bGduW0GQR1XS
CAS-1 NIrUXFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlrpTWM2OD1yLkK4N|A{KM7:TR?= MmfoV2FPT0WU
KURAMOCHI NUPTN4N3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1PNOWlEPTB;MD6yPFQyQSEQvF2= NET2SYlUSU6JRWK=
ACHN NGH5b5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWnFNXF3UUN3ME2wMlI6OzJ|IN88US=> M3\EenNCVkeHUh?=
HGC-27 MlvsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXjJR|UxRTBwMkmzOVMh|ryP M1nZeHNCVkeHUh?=
A172 MlTyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTBwMkm1O|ch|ryP NWnFeYtrW0GQR1XS
SNU-449 NIOzUXZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX\UTVJlUUN3ME2wMlI6QTZ2IN88US=> M3;ydnNCVkeHUh?=
SW982 NYLOVI9{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUfsVWZ2UUN3ME2wMlI6QTd6IN88US=> Ml3qV2FPT0WU
EFO-21 MoPyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIP2fZlKSzVyPUCuN|A1OTFizszN MnnDV2FPT0WU
NCI-H2030 M{TSb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYXXWYF{UUN3ME2wMlMyOTZ2IN88US=> NH3ZcndUSU6JRWK=
HT-144 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWDMNJlXUUN3ME2wMlMyOjhizszN Mo[wV2FPT0WU
MFE-280 MlrzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUSxU|lmUUN3ME2wMlMyPDV|IN88US=> M{HRenNCVkeHUh?=
SK-LU-1 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlnWTWM2OD1yLkOxOFY3KM7:TR?= MoW4V2FPT0WU
NCI-H2052 NEPkWGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUfJR|UxRTBwM{G0PFQh|ryP MUnTRW5ITVJ?
SK-HEP-1 NHnMPZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFz0PIpKSzVyPUCuN|M{PjhizszN NEDy[pZUSU6JRWK=
QIMR-WIL NFHqVJdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmjFTWM2OD1yLkOzOFI1KM7:TR?= MVjTRW5ITVJ?
A2780 M1nUSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGnVZVRKSzVyPUCuN|Q{ODRizszN Ml\JV2FPT0WU
ACN NVjqcZloT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkjDTWM2OD1yLkO0PFc{KM7:TR?= NE\KfJZUSU6JRWK=
BxPC-3 M4G3NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn;YTWM2OD1yLkO0PVg6KM7:TR?= NITzTZJUSU6JRWK=
BCPAP MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlTaTWM2OD1yLkO2NFAyKM7:TR?= NIfJZmxUSU6JRWK=
HOP-62 M4TzR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2LWPWlEPTB;MD6zOlExPiEQvF2= MXrTRW5ITVJ?
SW1710 M{DDUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV7JR|UxRTBwM{[0OVUh|ryP NHXldFVUSU6JRWK=
OPM-2 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVnJR|UxRTBwM{[0O|Mh|ryP MnroV2FPT0WU
DBTRG-05MG MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYS1[FNoUUN3ME2wMlM5ODV2IN88US=> NFrrPZNUSU6JRWK=
SK-MEL-24 MoHIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkPPTWM2OD1yLkO5O|kyKM7:TR?= NHjuXYdUSU6JRWK=
8305C NWnaZ5JJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MW\JR|UxRTBwM{m3PVMh|ryP NUW2[XE{W0GQR1XS
OVCAR-4 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3G1TGlEPTB;MD60NVU5PiEQvF2= NV3tOoFHW0GQR1XS
HLE NUi1OoZtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M33Tc2lEPTB;MD60NVg3KM7:TR?= MXXTRW5ITVJ?
NCI-H747 NV3KU|Y5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3S4RmlEPTB;MD60NlE{PyEQvF2= MWXTRW5ITVJ?
SW780 M2nQ[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWDJV45VUUN3ME2wMlQzOzR4IN88US=> NF\FVWhUSU6JRWK=
KYSE-150 NFLDRVVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4PUeGlEPTB;MD60NlQyPSEQvF2= NF;ES5NUSU6JRWK=
H4 M4\YTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYjJR|UxRTBwNEK0OVEh|ryP NF3J[lNUSU6JRWK=
SW1088 MkDES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVfCZWdjUUN3ME2wMlQ1OzlizszN M3XZdnNCVkeHUh?=
SF268 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYTJR|UxRTBwNES4OkDPxE1? M3TxTHNCVkeHUh?=
RT4 NUHjZoQxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYfJR|UxRTBwNEWxNVEh|ryP NFfqUG5USU6JRWK=
NCI-H522 M{L5PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHvmbJBKSzVyPUCuOFUzPyEQvF2= M1u2b3NCVkeHUh?=
LCLC-97TM1 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M16zbWlEPTB;MD60OlE6PSEQvF2= MlXEV2FPT0WU
CAL-39 MlPuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\MbWlEPTB;MD60OlUyQSEQvF2= MYjTRW5ITVJ?
CAL-120 NYDXPJdwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2XoO2lEPTB;MD60O|Y1OyEQvF2= MmrjV2FPT0WU
ESS-1 Moi4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYDu[YUzUUN3ME2wMlQ4QDJzIN88US=> NGjMVFBUSU6JRWK=
KARPAS-45 M2jQbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml7KTWM2OD1yLkS4PVM{KM7:TR?= MXHTRW5ITVJ?
DU-4475 NFnQWWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX7JR|UxRTBwNEm1NVEh|ryP MUjTRW5ITVJ?
VMRC-RCZ MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlr2TWM2OD1yLkS5PVA1KM7:TR?= NVPJSXpJW0GQR1XS
HOS NUWzV|hMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnzJTWM2OD1yLkWwN|Y2KM7:TR?= M{CxcHNCVkeHUh?=
MOLT-16 M2LVXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmfNTWM2OD1yLkWxPFA5KM7:TR?= NGjpXYJUSU6JRWK=
RPMI-6666 NGmyWZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnnxTWM2OD1yLkWyNVM2KM7:TR?= Mkn1V2FPT0WU
K052 M2rTZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mo\QTWM2OD1yLkWyNVQh|ryP M3TndXNCVkeHUh?=
EHEB NEH3NIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NE\yN4hKSzVyPUCuOVIyQDJizszN MV7TRW5ITVJ?
MFH-ino MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHPqTYZKSzVyPUCuOVI{PTFizszN MY\TRW5ITVJ?
A4-Fuk MnHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV3JR|UxRTBwNUK1Nlgh|ryP M{i3cHNCVkeHUh?=
SW1417 M{OwPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml;4TWM2OD1yLkWyO|gyKM7:TR?= NUP4UmpzW0GQR1XS
DoTc2-4510 Mlf6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYXJR|UxRTBwNUS5OVgh|ryP MoDWV2FPT0WU
TE-12 NXqyeXM{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV:0WJJLUUN3ME2wMlU2PzN3IN88US=> NYPUXIpQW0GQR1XS
8-MG-BA M{O1Nmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXTJR|UxRTBwNU[wOVYh|ryP MX\TRW5ITVJ?
ECC12 NFWzdZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUTJR|UxRTBwNU[1OVgh|ryP NVroTW8zW0GQR1XS
CHL-1 NY\6dVlST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWHvPXVWUUN3ME2wMlU4PDZ|IN88US=> Mm[3V2FPT0WU
LCLC-103H M3zUV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3jHdmlEPTB;MD61PFM1PCEQvF2= NEnOcFJUSU6JRWK=
OS-RC-2 M1[3bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYrKWnlyUUN3ME2wMlU5Ozd7IN88US=> Mor1V2FPT0WU
RO82-W-1 NGfrOVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkHpTWM2OD1yLkW5OlE2KM7:TR?= MmrUV2FPT0WU
A3-KAW MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXLJR|UxRTBwNkG0Olch|ryP NFnkSJpUSU6JRWK=
NCCIT MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTBwNkG3NVUh|ryP NFPHXHdUSU6JRWK=
IST-SL2 NFLqSJdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4fYWmlEPTB;MD62NlUzOiEQvF2= MYTTRW5ITVJ?
GI-ME-N NFi3WoFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWXVN2w1UUN3ME2wMlY{ODZ7IN88US=> MUnTRW5ITVJ?
ES6 MoPVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlLHTWM2OD1yLk[zNlk2KM7:TR?= NWjU[Y9TW0GQR1XS
BL-41 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFLjcnJKSzVyPUCuOlM{PTJizszN M1u0[HNCVkeHUh?=
Ca-Ski MlXKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml3WTWM2OD1yLk[0PFEh|ryP NWm1ZoI5W0GQR1XS
HOP-92 NYm1fWE4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUTJR|UxRTBwNkW2O|Ih|ryP MmHwV2FPT0WU
SK-LMS-1 MlX2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4nzfGlEPTB;MD62OlQ4KM7:TR?= MWPTRW5ITVJ?
EW-13 NHTaVWpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHj4UlZKSzVyPUCuOlY4PzlizszN NVjCTIlxW0GQR1XS
647-V MkHuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3vJZ2lEPTB;MD62PFE1QCEQvF2= NVjXWIZDW0GQR1XS
JiyoyeP-2003 MkfHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIf4NmdKSzVyPUCuOlk4OzhizszN NWnoXpU6W0GQR1XS
WSU-NHL NX3QUFR7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mnn1TWM2OD1yLkewPFg4KM7:TR?= NInqbJNUSU6JRWK=
U-698-M NXr1Sod5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVG4WYdNUUN3ME2wMlcyODZ|IN88US=> MV;TRW5ITVJ?
HC-1 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHm4Zm1KSzVyPUCuO|I1ODVizszN MnjNV2FPT0WU
8505C NXm2SHlJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml\WTWM2OD1yLkeyO|QyKM7:TR?= NWfyZWJUW0GQR1XS
HUTU-80 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTBwN{OzOFkh|ryP M3;FVHNCVkeHUh?=
LB1047-RCC Mn31S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlrKTWM2OD1yLkezOVM5KM7:TR?= MVfTRW5ITVJ?
GAMG M3jVfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1PRd2lEPTB;MD63N|Y2OyEQvF2= MoXTV2FPT0WU
CAL-12T NXm2RmJzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mo[5TWM2OD1yLkezPFc4KM7:TR?= MXTTRW5ITVJ?
NCI-SNU-1 NWTYNYZ1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoPRTWM2OD1yLke3Nlc5KM7:TR?= MUjTRW5ITVJ?
HTC-C3 NGK1c5hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUjyW2NqUUN3ME2wMlc4PDVzIN88US=> NIjnelJUSU6JRWK=
HPAF-II NWL2XJhwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF2zeWZKSzVyPUCuO|c2ODFizszN MXvTRW5ITVJ?
KGN NW\wXGtxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWTDR4FJUUN3ME2wMlc5ODhzIN88US=> M4jweHNCVkeHUh?=
EFO-27 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTBwN{i3N|Mh|ryP MXnTRW5ITVJ?
MEL-HO NWT0fI1tT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3G3b2lEPTB;MD63PVQ1QSEQvF2= NV\4[I5DW0GQR1XS
KYSE-270 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX3WdmFTUUN3ME2wMlgxPTJ7IN88US=> MWDTRW5ITVJ?
NCI-H1755 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEG2TWRKSzVyPUCuPFA4OTRizszN M1:0SnNCVkeHUh?=
MFM-223 NGnhWVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MofwTWM2OD1yLkixOFA4KM7:TR?= NXzNcINzW0GQR1XS
G-361 NV[5UotZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1XwTGlEPTB;MD64NVg6PyEQvF2= MnLuV2FPT0WU
ETK-1 NFnCeWpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3TDUGlEPTB;MD64NlQ1OSEQvF2= MlnOV2FPT0WU
LU-99A MnvnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTBwOES3NFEh|ryP MlfNV2FPT0WU
IST-MEL1 M1LsZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3Lq[mlEPTB;MD64OVc{OiEQvF2= NVTHSWd[W0GQR1XS
L-540 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnrQTWM2OD1yLki1PFAyKM7:TR?= M3jCNXNCVkeHUh?=
U-2-OS NIric4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYfJR|UxRTBwOEW4OFYh|ryP M3fyZ3NCVkeHUh?=
HT-1376 MoX3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFjVd5FKSzVyPUCuPFYxPTFizszN M1jyVHNCVkeHUh?=
COLO-680N Moj2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF;QWlRKSzVyPUCuPFc6OzNizszN MXfTRW5ITVJ?
NCI-H1581 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIWyboNKSzVyPUCuPFkzQTdizszN NH7nOY9USU6JRWK=
HuCCT1 NX7NXoFLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWPLT5JyUUN3ME2wMlg6PTR6IN88US=> NITEflZUSU6JRWK=
BB30-HNC MnHOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFrG[JRKSzVyPUCuPVI1PjlizszN MXrTRW5ITVJ?
NCI-H2347 NEP5dnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFfDOmdKSzVyPUCuPVMzQTJizszN M{jHOXNCVkeHUh?=
G-401 MmHqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWPJR|UxRTBwOUO2PVUh|ryP M4H2cHNCVkeHUh?=
NCI-H358 NWP4PXo4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUXJR|UxRTBwOUWwNVQh|ryP Mn;OV2FPT0WU
HCC1395 MoP2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWfJR|UxRTBwOUW0OlEh|ryP M2\uOHNCVkeHUh?=
J82 Ml62S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXPJR|UxRTBwOUW1OFMh|ryP MlPVV2FPT0WU
KE-37 NUXnT2d4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2HuZmlEPTB;MD65OlM5PyEQvF2= M1[wNHNCVkeHUh?=
NOMO-1 M3LQe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXPJR|UxRTBwOU[1OlQh|ryP NX;NdnU1W0GQR1XS
ML-2 NF\nOHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkfsTWM2OD1yLkm5O|Uh|ryP NEK3VGtUSU6JRWK=
SW872 MlvHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4TNdmlEPTB;MD65PVc4PSEQvF2= MliyV2FPT0WU
KYSE-520 MmG0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4PofGlEPTB;MT6wNFQ6PCEQvF2= MVvTRW5ITVJ?
HL-60 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M330XmlEPTB;MT6wNFk4KM7:TR?= NFLkO5FUSU6JRWK=
HDLM-2 NHLGNFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2e3RWlEPTB;MT6wNVI2OiEQvF2= NGjLfYxUSU6JRWK=
MIA-PaCa-2 NULY[3lWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH2yW3VKSzVyPUGuNFE{PzVizszN NXfoOIFYW0GQR1XS
TCCSUP NVzododOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFf6W2lKSzVyPUGuNFE4OzJizszN MXfTRW5ITVJ?
SH-4 NFnYfnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnvZTWM2OD1zLkCyNlQ1KM7:TR?= NWTiOVlxW0GQR1XS
MG-63 M3TDZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFnjZotKSzVyPUGuNFI3OTZizszN MnLOV2FPT0WU
NB6 M{TkO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTFwMEOxNFkh|ryP MlTuV2FPT0WU
CAL-54 M3nL[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2S4TWlEPTB;MT6wN|k2QSEQvF2= NGDCOVlUSU6JRWK=
DU-145 MojlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mkf0TWM2OD1zLkC4NFc{KM7:TR?= M3frTXNCVkeHUh?=
HCE-4 M4Wwe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV\WR2RGUUN3ME2xMlA6Ojh4IN88US=> NI\PR|hUSU6JRWK=
U-266 NEPDfFlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2f2[2lEPTB;MT6wPVY{OyEQvF2= Mn[1V2FPT0WU
HT-1197 MnPIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoriTWM2OD1zLkGxOFM5KM7:TR?= NX;OXmh7W0GQR1XS
EW-1 NIO0OGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MojCTWM2OD1zLkG0NVI5KM7:TR?= M1u4cnNCVkeHUh?=
MHH-NB-11 NUjiZ2ltT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmDJTWM2OD1zLkG1N|Y5KM7:TR?= NEHuVXhUSU6JRWK=
NCI-H2405 NEf0cHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1LFUmlEPTB;MT6xOlE3KM7:TR?= M1\mZXNCVkeHUh?=
COLO-668 NHfLbI1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXTJR|UxRTFwMU[0PUDPxE1? MXHTRW5ITVJ?
IMR-5 NGL6XGxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYLGbZJXUUN3ME2xMlE3QTN4IN88US=> M1\ne3NCVkeHUh?=
ARH-77 MljzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4C2NGlEPTB;MT6yNlkzPCEQvF2= MXrTRW5ITVJ?
BHT-101 NXT0RZdJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlnmTWM2OD1zLkKzOFkh|ryP NYWzNYhTW0GQR1XS
SCC-25 MljtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmD0TWM2OD1zLkKzOVM3KM7:TR?= NWrNblBKW0GQR1XS
NTERA-S-cl-D1 NG\zfVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHvYd21KSzVyPUGuNlQ{PDZizszN M2rTdnNCVkeHUh?=
MKN28 NEHwOJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHTYUnZKSzVyPUGuNlU3OzZizszN MnvBV2FPT0WU
KS-1 M3jBe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NW\mWphVUUN3ME2xMlI5OjZ7IN88US=> NFnY[2pUSU6JRWK=
NCI-H1734 NIO4[|VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mni5TWM2OD1zLkK4PVE{KM7:TR?= NGnLZo9USU6JRWK=
ES7 NF;QbHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{j4O2lEPTB;MT6yPVU1OiEQvF2= MUPTRW5ITVJ?
NCI-H838 MnfsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVLJR|UxRTFwM{C2NVUh|ryP NIrHUY5USU6JRWK=
HEC-1 M4C0Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXLJR|UxRTFwM{O3OVUh|ryP NF;OO41USU6JRWK=
ME-180 M4ey[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NI\URY1KSzVyPUGuN|c6QTNizszN M4Kx[XNCVkeHUh?=
MMAC-SF M12wTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTFwM{m1PVUh|ryP MUfTRW5ITVJ?
IA-LM M3\1VGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmjnTWM2OD1zLkSwPVE1KM7:TR?= MWHTRW5ITVJ?
MN-60 M2e4T2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEDvcpBKSzVyPUGuOFMyOTRizszN MWDTRW5ITVJ?
SIMA NIiyS45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYfUPZNXUUN3ME2xMlQ5Pjh5IN88US=> Ml\NV2FPT0WU
NCI-H1770 M4ixU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NETkWIxKSzVyPUGuOVIxPTRizszN M{HyNXNCVkeHUh?=
ONS-76 M3TZTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWTYdZhbUUN3ME2xMlUzOzFzIN88US=> M2P3fXNCVkeHUh?=
LB771-HNC NWLDe2NbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV3JR|UxRTFwNUO5NFYh|ryP NWL1ZXFRW0GQR1XS
SW48 MlLVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnvqTWM2OD1zLkW0NlQ{KM7:TR?= Mli5V2FPT0WU
KYSE-140 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX;uT|IzUUN3ME2xMlU2PzRzIN88US=> NYC4RmpyW0GQR1XS
SW626 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MojsTWM2OD1zLkW4NVYh|ryP NHTMVYxUSU6JRWK=
MC-CAR NWLJO3hGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUfJR|UxRTFwNUi2OlMh|ryP M33m[nNCVkeHUh?=
D-336MG NEmxcIFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGrzenFKSzVyPUGuOlI6PCEQvF2= MV3TRW5ITVJ?
SK-MEL-3 M1;JdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTFwNkO5NFIh|ryP NEfhcIFUSU6JRWK=
MHH-PREB-1 NWjYZZBJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mlz1TWM2OD1zLk[0OFc{KM7:TR?= MXTTRW5ITVJ?
Calu-1 NXeyd3l3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkjkTWM2OD1zLk[1N|g3KM7:TR?= M2riN3NCVkeHUh?=
HCC1806 NHzo[npIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYm1bVZOUUN3ME2xMlY3PjFzIN88US=> NInjWJpUSU6JRWK=
A101D NXHJcFVnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1vLOGlEPTB;MT62Olc5OSEQvF2= M4fUS3NCVkeHUh?=
A704 NWTQTVk2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoXiTWM2OD1zLk[4N|EyKM7:TR?= NEK3XpBUSU6JRWK=
LB831-BLC MmPOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml3JTWM2OD1zLk[5PFU1KM7:TR?= NEfXWVBUSU6JRWK=
RL95-2 M1rmXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH;yVFZKSzVyPUGuO|E1PjNizszN NX20UG5TW0GQR1XS
RPMI-2650 NX76OFZLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHe4T4FKSzVyPUGuO|I4OTlizszN NHfXdnpUSU6JRWK=
NH-12 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MU\JR|UxRTFwN{O0Nlch|ryP MUfTRW5ITVJ?
AGS Mnq3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXSxWWs3UUN3ME2xMlc3OzV6IN88US=> Mle5V2FPT0WU
NEC8 NXz5W4c2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFvVTpBKSzVyPUGuO|g6QTVizszN MXrTRW5ITVJ?
NCI-H2009 NVPycI03T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVuwT2hQUUN3ME2xMlc6PzJzIN88US=> MYDTRW5ITVJ?
A498 NGTKWnVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2i5O2lEPTB;MT64NVI5OiEQvF2= NXy5c2dyW0GQR1XS
NCI-H810 NH7LUY1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\FNGh2UUN3ME2xMlgyPjB4IN88US=> M{S4THNCVkeHUh?=
SK-NEP-1 M4jobWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYHJR|UxRTFwOEO3Olch|ryP MkXHV2FPT0WU
D-542MG M3PiPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXvIfmR7UUN3ME2xMlg2QDVzIN88US=> MnfQV2FPT0WU
KNS-42 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnG4TWM2OD1zLki2NlY3KM7:TR?= NUKx[VlFW0GQR1XS
NCI-H2452 MoPiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoG2TWM2OD1zLki5NFc1KM7:TR?= MoHWV2FPT0WU
SK-MEL-2 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGHOfYZKSzVyPUGuPVAzPzFizszN NITpWIZUSU6JRWK=
OVCAR-5 NFzub3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\Ed|VkUUN3ME2xMlkxPjd3IN88US=> NFyxOoNUSU6JRWK=
SNG-M NFXSOpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3zuNWlEPTB;MT65OVg2QCEQvF2= NFGzOmFUSU6JRWK=
A673 NX7KWGtCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUPwRYxIUUN3ME2xMlk4PTF4IN88US=> MnvRV2FPT0WU
L-428 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\LcZVKSzVyPUGuPVkyPzlizszN MlX3V2FPT0WU
KM-H2 M{nCb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWLHbIhiUUN3ME2yMlAyODlizszN NVfOT4VQW0GQR1XS
MC-IXC MnvnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV3MNXhyUUN3ME2yMlAzOjd|IN88US=> MV7TRW5ITVJ?
COLO-678 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnvZTWM2OD1{LkC0NlA4KM7:TR?= MWnTRW5ITVJ?
MEL-JUSO MnnoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUHJR|UxRTJwMEe4OVEh|ryP MnXBV2FPT0WU
HCC38 NVzBcWs2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUjsSng3UUN3ME2yMlA5PDN|IN88US=> M{LpSnNCVkeHUh?=
UACC-62 MmOyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH:wPGRKSzVyPUKuNFg5PTVizszN NYHz[YRzW0GQR1XS
OAW-42 M{ewZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVHPTZFGUUN3ME2yMlA6PzFzIN88US=> Mn;KV2FPT0WU
LB996-RCC MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2K5eWlEPTB;Mj6xN|gyPyEQvF2= MUfTRW5ITVJ?
COR-L105 NEPLOWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUXIbZdIUUN3ME2yMlE3Ozd|IN88US=> NFXyT|dUSU6JRWK=
RCC10RGB MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVnLcZRRUUN3ME2yMlE5PTd4IN88US=> NX;OSJhuW0GQR1XS
A431 NVW3bJY2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWjJR|UxRTJwMUmwNVkh|ryP M4DyR3NCVkeHUh?=
NCI-H292 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF;3R2RKSzVyPUKuNlM6PTFizszN M1r0[3NCVkeHUh?=
SK-UT-1 NXfWSotxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmXVTWM2OD1{LkOzNVg1KM7:TR?= MVPTRW5ITVJ?
PANC-08-13 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHPGWJhKSzVyPUKuN|MzOzVizszN MUnTRW5ITVJ?
ST486 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlrVTWM2OD1{LkSxNFQ5KM7:TR?= M4rwOnNCVkeHUh?=
SJSA-1 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3i2fmlEPTB;Mj60NVI4OSEQvF2= Mm\FV2FPT0WU
RKO MoDLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn7hTWM2OD1{LkSyNFI6KM7:TR?= NHjwRnlUSU6JRWK=
NCI-H1793 NEfRPHZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYjJR|UxRTJwNESwNlkh|ryP M1\nOHNCVkeHUh?=
639-V NIXPOpJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGrjU3dKSzVyPUKuOFU{QDJizszN NGn6TZlUSU6JRWK=
ES3 M320Tmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3PlOmlEPTB;Mj60PVc{PyEQvF2= MlTtV2FPT0WU
NCI-H1792 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJR|UxRTJwNU[4NlYh|ryP NFzN[2ZUSU6JRWK=
NCI-H1651 MkXkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlrlTWM2OD1{LkW4NlEh|ryP MV\TRW5ITVJ?
SN12C NIj6VWFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTJwNUi0PFch|ryP NGK3UnFUSU6JRWK=
COLO-679 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUOzVmZQUUN3ME2yMlU5PjB3IN88US=> NUi2OnIyW0GQR1XS
U-118-MG NX\wSFNIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXXJR|UxRTJwNUi4O|Ih|ryP MnLlV2FPT0WU
Ramos-2G6-4C10 M1vQXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MojlTWM2OD1{Lk[0PFA4KM7:TR?= MUPTRW5ITVJ?
HCT-15 NHjpPVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2m2XmlEPTB;Mj62PFc6OiEQvF2= NIL6epBUSU6JRWK=
MDA-MB-157 M4\ETmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NETuVlJKSzVyPUKuO|A4PDdizszN NFXDXpBUSU6JRWK=
K5 NXvW[Jg3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4GwNGlEPTB;Mj63NVg1PSEQvF2= NYnRPZdtW0GQR1XS
MKN45 NIT3NY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NI[3cYFKSzVyPUKuO|M{PjZizszN M2rBN3NCVkeHUh?=
DMS-273 Mm\pS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlPZTWM2OD1{Lke1OlMzKM7:TR?= MnnSV2FPT0WU
C8166 M3;oSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYjXb5VqUUN3ME2yMlc5PTF|IN88US=> MWjTRW5ITVJ?
Calu-3 M2jYOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmPPTWM2OD1{Lke4PVY6KM7:TR?= NIfufHdUSU6JRWK=
SNB75 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3LxN2lEPTB;Mj64PFU{PSEQvF2= MYnTRW5ITVJ?
BFTC-905 MkLjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mkf1TWM2OD1{LkmwNVkyKM7:TR?= M1nKUnNCVkeHUh?=
C-4-II Mo\aS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmrVTWM2OD1{LkmxN|U{KM7:TR?= NWPFfHBzW0GQR1XS
MS-1 Mlv6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml2wTWM2OD1{Lkm2O|Y6KM7:TR?= MUPTRW5ITVJ?
A375 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVnSNYRZUUN3ME2zMlA5OTh2IN88US=> MoHEV2FPT0WU
KYSE-70 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmXDTWM2OD1|LkC4PFgzKM7:TR?= M1iwU3NCVkeHUh?=
KYSE-510 NG\QZVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIXIV2dKSzVyPUOuNVA6QTVizszN NU\KWZhrW0GQR1XS
LN-405 M1HUb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXnzdm5oUUN3ME2zMlE{PTF6IN88US=> NF;Ye2hUSU6JRWK=
BOKU MofZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4HaV2lEPTB;Mz6xOFI2PiEQvF2= MlHQV2FPT0WU
TE-10 M1fHOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH3Zbo9KSzVyPUOuNVc{PjJizszN NWHhUVZmW0GQR1XS
MKN1 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXnwOJVMUUN3ME2zMlE5PDh|IN88US=> NVTjfFUyW0GQR1XS
M059J M13U[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYHKUFNDUUN3ME2zMlIxOTd|IN88US=> NFLGO5VUSU6JRWK=
GOTO NHrSc5lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYP5TFI6UUN3ME2zMlIzODN7IN88US=> MUHTRW5ITVJ?
DK-MG NH30eGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYDJR|UxRTNwMkW5O|Yh|ryP NVy3NJZ5W0GQR1XS
NCI-H727 NVrUbId[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHnGTXJKSzVyPUOuNlY2QCEQvF2= NWPabXl5W0GQR1XS
NB12 M3vKR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXzJR|UxRTNwM{OyNlQh|ryP NYjBTYF4W0GQR1XS
DOK NWDoZVduT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYTJR|UxRTNwM{[xPFYh|ryP NH;0dndUSU6JRWK=
KYSE-410 MlnjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NI\XSXRKSzVyPUOuN|YzQDdizszN M1X4S3NCVkeHUh?=
AM-38 Mn;ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxRTNwM{iwOVEh|ryP NITZN2FUSU6JRWK=
GR-ST MmGzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVXRZZRbUUN3ME2zMlQ2PzN{IN88US=> NYTNdo1HW0GQR1XS
D-247MG NYOzcYVKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXPURWRFUUN3ME2zMlQ5OjZ|IN88US=> M4ewUXNCVkeHUh?=
TE-8 NGHnUGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1LCWGlEPTB;Mz60PVM{OyEQvF2= NFT2O2xUSU6JRWK=
LS-411N MnzrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUHJR|UxRTNwNEm2PVIh|ryP MofMV2FPT0WU
SK-MES-1 NXXXOGNCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmnzTWM2OD1|LkW2OFM{KM7:TR?= NGXNdIFUSU6JRWK=
SF295 Mlf3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn;hTWM2OD1|Lk[xOVUzKM7:TR?= NIfwcnhUSU6JRWK=
SK-MEL-30 NHfzWlVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX3JR|UxRTNwNkW5NlEh|ryP MnTBV2FPT0WU
LB2241-RCC M1XzeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnL2TWM2OD1|Lk[2NlYh|ryP MnmyV2FPT0WU
PC-14 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3HaOWlEPTB;Mz62OlQ{PyEQvF2= MXjTRW5ITVJ?
EW-7 NVHmUXJxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUnqeHlMUUN3ME2zMlY4Pjl|IN88US=> NFPjUndUSU6JRWK=
NMC-G1 NHXpSpBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVXJR|UxRTNwN{G4N|ch|ryP MXzTRW5ITVJ?
TE-441-T NW\nW4Q{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVnmUoJJUUN3ME2zMlc{ODJ6IN88US=> NFOy[5VUSU6JRWK=
NCI-H1618 MnTpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml;LTWM2OD1|LkixPFc2KM7:TR?= MlTqV2FPT0WU
PANC-03-27 NFnmb3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mkn6TWM2OD1|LkixPVE3KM7:TR?= MX7TRW5ITVJ?
NCI-H2228 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJR|UxRTNwOEOxNlYh|ryP MnzEV2FPT0WU
CAPAN-1 NGXiUnpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYC0dWw6UUN3ME2zMlg4ODB7IN88US=> NYTIOWNCW0GQR1XS
KLE M1fPdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{\leGlEPTB;Mz65NFY4KM7:TR?= NX2xVYQxW0GQR1XS
Becker NFOxeHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUfQSHlUUUN3ME2zMlkzQDR7IN88US=> M2H2UXNCVkeHUh?=
SK-PN-DW MkKwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml\VTWM2OD12LkC3PVc1KM7:TR?= M1HtNXNCVkeHUh?=
Hs-578-T MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2f3TWlEPTB;ND6wPFMxPiEQvF2= MUTTRW5ITVJ?
RS4-11 NIr1dIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHe4dWhKSzVyPUSuNVEzPTVizszN MoSxV2FPT0WU
D-502MG NEDLSnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnSyTWM2OD12LkG2PVk4KM7:TR?= NGnwW5hUSU6JRWK=
GI-1 NX7pSZF7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnLQTWM2OD12LkK4Nlk6KM7:TR?= NF3INm5USU6JRWK=
NCI-H209 MoPPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHXVTnVKSzVyPUSuN|M4QCEQvF2= MkXKV2FPT0WU
SK-OV-3 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGLP[pBKSzVyPUSuOFgyPDlizszN M17KVHNCVkeHUh?=
LOUCY M{XlZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWrJR|UxRTRwNEi0N|Ih|ryP M4DE[nNCVkeHUh?=
NCI-H69 NWTl[FBnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWDRNpd4UUN3ME20MlUyPzl|IN88US=> Ml\4V2FPT0WU
SCC-9 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWG5UnNiUUN3ME20MlU{OTd{IN88US=> MlfvV2FPT0WU
NCI-H526 NFXXXYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYTtNpROUUN3ME20MlU6Ojl|IN88US=> M1rWSXNCVkeHUh?=
NCI-H2170 NI\Jc3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmPJTWM2OD12Lk[2O|cyKM7:TR?= MmG0V2FPT0WU
SR M1nZbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mln1TWM2OD12LkewNFQ5KM7:TR?= NUX3XJRMW0GQR1XS
CMK NUnFO|c3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUjJR|UxRTRwN{KxNFEh|ryP MnK2V2FPT0WU
COLO-829 M{LtfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlvnTWM2OD12Lke3NFQ{KM7:TR?= MlTPV2FPT0WU
HuO-3N1 NELUeYlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml\HTWM2OD12LkizNlgyKM7:TR?= NFfwR3NUSU6JRWK=
5637 NXPoT4dUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{nW[WlEPTB;ND65NFQ5PyEQvF2= MmTVV2FPT0WU
A253 Mo\nS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2PM[2lEPTB;ND65O|cxQCEQvF2= M3PCd3NCVkeHUh?=
NB10 NIS3VGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1PsR2lEPTB;NT6wO|Q6PyEQvF2= MknzV2FPT0WU
SF539 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVviVZpSUUN3ME21MlA6QTV7IN88US=> MYfTRW5ITVJ?
HAL-01 MoXOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnHrTWM2OD13LkG0OlQ2KM7:TR?= MYXTRW5ITVJ?
MHH-ES-1 NUjSVnVGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3W1dWlEPTB;NT6xOlkzPSEQvF2= NFjjcJRUSU6JRWK=
DEL NV:3cWV{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYrye2R4UUN3ME21MlI4PTh{IN88US=> MmDYV2FPT0WU
NCI-H1299 M{DLbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGPaTWFKSzVyPUWuN|UxODdizszN MYXTRW5ITVJ?
ChaGo-K-1 NFXOUmNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLpN2ZKSzVyPUWuN|UyODdizszN NFnOd|NUSU6JRWK=
HMV-II M{Xyfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mk[3TWM2OD13LkO5OFMh|ryP MUDTRW5ITVJ?
NB69 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2LmRmlEPTB;NT6zPVY{OSEQvF2= Mo\TV2FPT0WU
NCI-H1882 MorMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWXJR|UxRTVwNEOzOlQh|ryP MYXTRW5ITVJ?
SNU-475 NWfoWVZwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIPzSFFKSzVyPUWuOFcyPzFizszN NXfNSIdTW0GQR1XS
RXF393 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHqxRXJKSzVyPUWuOFg1QTRizszN NXntfI1FW0GQR1XS
CAL-51 NVPmZ2xxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV:xcGpmUUN3ME21MlYzQDV|IN88US=> MmTJV2FPT0WU
SW1573 M1jENGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmfxTWM2OD13Lk[zOVM1KM7:TR?= MmLHV2FPT0WU
GCT NGnic|VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFvkOXVKSzVyPUWuO|U6OjlizszN NXfrOIpIW0GQR1XS
COR-L88 NVfXcld[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmTRTWM2OD13Lke2PFQ3KM7:TR?= M{[xdnNCVkeHUh?=
MDA-MB-134-VI MoTXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MojVTWM2OD13Lki3OVM3KM7:TR?= M3vSTnNCVkeHUh?=
NB5 M1zOZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NELzSIpKSzVyPUWuPVI1PCEQvF2= MofhV2FPT0WU
GMS-10 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{j6UmlEPTB;NT65Olg3OSEQvF2= M4nmcXNCVkeHUh?=
CHP-212 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkPWTWM2OD14LkS4NlY4KM7:TR?= M1foNnNCVkeHUh?=
TE-11 MlzUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUHUR|N7UUN3ME22MlU2OTh{IN88US=> MnvEV2FPT0WU
SW962 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVf4b5ZKUUN3ME22MlY2Pzd2IN88US=> MX\TRW5ITVJ?
MZ2-MEL MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVPJR|UxRTZwOEKwNVEh|ryP M4PMc3NCVkeHUh?=
C-33-A NEH6[2RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXG2b21qUUN3ME22MlkyPjh6IN88US=> MYTTRW5ITVJ?
IGR-1 M2HFNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3zzTWlEPTB;Nj65O|gzPiEQvF2= NEDUU5VUSU6JRWK=
MOLT-4 NXrYRpdyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NInCW4pKSzVyPUeuNVU1ODZizszN MXvTRW5ITVJ?
NCI-H1650 NHLueZZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MofsTWM2OD15LkK3NFQ3KM7:TR?= NHTnbVBUSU6JRWK=
AsPC-1 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUTCe|RyUUN3ME23MlI5PjB3IN88US=> M{m0ZnNCVkeHUh?=
SNU-C2B M1jvR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGTnR49KSzVyPUeuNlk2PzFizszN NH\adHZUSU6JRWK=
MKN7 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{ftVmlEPTB;Nz6zO|I{PSEQvF2= Ml60V2FPT0WU
SW620 NVnMTlFuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmXZTWM2OD15LkO4NlA2KM7:TR?= NF;aU5FUSU6JRWK=
SK-MEL-28 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2L2eGlEPTB;Nz60NFc6QCEQvF2= MmLKV2FPT0WU
TE-6 M2fMbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF7BPFRKSzVyPUeuOFQ6ODhizszN MVvTRW5ITVJ?
D-263MG M4TmSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmHETWM2OD15LkS1O|YzKM7:TR?= NWXyU2ZYW0GQR1XS
NCI-H1355 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3XnU2lEPTB;Nz63O|AzQSEQvF2= NITIcYxUSU6JRWK=
DSH1 NF\VdYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVjJR|UxRTdwN{m3OlIh|ryP M37QPHNCVkeHUh?=
NCI-H460 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFvvVm9KSzVyPUiuNFA3QTRizszN MmrMV2FPT0WU
NCI-H1563 M2S2N2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWfwSnU2UUN3ME24MlA4PTB6IN88US=> MUDTRW5ITVJ?
SW948 NGPhdHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWrW[XJpUUN3ME24MlExPzR2IN88US=> NEmxcYdUSU6JRWK=
LK-2 M4HLOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkfxTWM2OD16LkGyPFM{KM7:TR?= NEnQ[2lUSU6JRWK=
HT-1080 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYTJR|UxRThwMUOxO|Uh|ryP M3rUO3NCVkeHUh?=
NCI-H441 M{iyW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWG2WVdRUUN3ME24MlE6OyEQvF2= M2nxW3NCVkeHUh?=
HSC-4 NUDlUVQ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnLvTWM2OD16LkK4O|Ih|ryP MkXQV2FPT0WU
LXF-289 MnfWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVrJR|UxRThwM{W5OFMh|ryP M3LNWnNCVkeHUh?=
MRK-nu-1 M3j0bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGXnfmxKSzVyPUiuN|Y{ODRizszN MV7TRW5ITVJ?
no-11 NXTvO5p[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHHLPJhKSzVyPUiuOFcyOzNizszN Mlq2V2FPT0WU
SNU-387 M2DxOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3fyOWlEPTB;OD62N|I1PiEQvF2= M2HEfXNCVkeHUh?=
Detroit562 NHqyeVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NULUW493UUN3ME24Mlc2PDV3IN88US=> MYTTRW5ITVJ?
SW954 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH[xRZVKSzVyPUiuO|Y5OzJizszN Moi2V2FPT0WU
P12-ICHIKAWA MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYD0SHhIUUN3ME24Mlc5QTRizszN M3fPS3NCVkeHUh?=
TE-9 M4eze2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4TaS2lEPTB;OD64NVA3OiEQvF2= MVnTRW5ITVJ?
NB13 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVTJR|UxRThwOEO3PVYh|ryP M1r0d3NCVkeHUh?=
BPH-1 NIfJfIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLJOYJKSzVyPUiuPFUxQDFizszN MnW1V2FPT0WU
KMOE-2 NXT6N2l4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlLzTWM2OD16Lki3PFkzKM7:TR?= MkDLV2FPT0WU
RPMI-8402 NW\vR2dDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NE[5THRKSzVyPUiuPFk6OjZizszN MljBV2FPT0WU
OVCAR-3 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2PhVmlEPTB;OD65O|c{OiEQvF2= NFnQ[pVUSU6JRWK=
NCI-H2196 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHrTZnZKSzVyPUiuPVg3ODZizszN NWLNPFlOW0GQR1XS
MZ7-mel NYL1RZpNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnHlTWM2OD17LkCzOFYh|ryP MWrTRW5ITVJ?
GP5d M1jLcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn;jTWM2OD17LkC2N|E{KM7:TR?= MlexV2FPT0WU
NCI-N87 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUXJR|UxRTlwNES3N|Eh|ryP MUDTRW5ITVJ?
EW-16 NFjKdpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGrWS4VKSzVyPUmuOFQ5PDhizszN MkjLV2FPT0WU
Calu-6 NUSyWFJ{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{PQcWlEPTB;OT60PVcxOyEQvF2= M2\yd3NCVkeHUh?=
LC4-1 Mk\QS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXzJR|UxRTlwNkK1O{DPxE1? NYK4SW1lW0GQR1XS
CCRF-CEM M3fQfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGPFVYNKSzVyPUmuOlg4PjZizszN MoLEV2FPT0WU
BC-1 M4HNcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXT3VmZkUUN3ME25Mlc5QTlizszN MWrTRW5ITVJ?
NCI-SNU-16 NH;KNHZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4DrbGlEPTB;OT63PVQ6PSEQvF2= Mm\iV2FPT0WU
NCI-H28 NGqzeIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV\JR|UxRTlwOES5N|Mh|ryP M1f4eHNCVkeHUh?=
SBC-1 MmjkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\IbYxKSzVyPUGwMlA4OiEQvF2= NX:wb3JNW0GQR1XS
TUR MoPBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mme3TWM2OD1zMD6xOlU4KM7:TR?= MVLTRW5ITVJ?
MDA-MB-231 NYXyWmkxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnrQTWM2OD1zMD6yNVE1KM7:TR?= Mkm5V2FPT0WU
C3A NULnS25lT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoOxTWM2OD1zMD6zNVc6KM7:TR?= NF3Xb4JUSU6JRWK=
SW1990 NVPN[4lNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV;MWVVbUUN3ME2xNE4{OjhizszN M4jGdnNCVkeHUh?=
NCI-H1993 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWnJR|UxRTFyLkW2PVMh|ryP MV7TRW5ITVJ?
SK-CO-1 NGDDdpFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUCzbnhHUUN3ME2xNE44PzdizszN M1nRfnNCVkeHUh?=
OAW-28 M3;abWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTFyLkm4PFgh|ryP NEn6UZNUSU6JRWK=
HN NEXLbnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFKxZpVKSzVyPUGxMlEyOzFizszN NGi3OWNUSU6JRWK=
NCI-H1304 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYXyWGNpUUN3ME2xNU4yPTd4IN88US=> NHWybW1USU6JRWK=
Daoy NHX6RZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVvJR|UxRTFzLkSzN|Yh|ryP M4KyNnNCVkeHUh?=
VA-ES-BJ NHTWVHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVvJR|UxRTFzLkexPVUh|ryP Mo[xV2FPT0WU
MCF7 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHf6dnNKSzVyPUGxMlgyOjZizszN NXS2XlB[W0GQR1XS
VM-CUB-1 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVvxb4g1UUN3ME2xNU46ODlzIN88US=> NYThXoc4W0GQR1XS
IPC-298 NV;UW41jT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MULJR|UxRTFzLkmzPFMh|ryP NYPDTplIW0GQR1XS
NCI-H2126 M1e3NWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoP1TWM2OD1zMj6wNlE5KM7:TR?= M4DxT3NCVkeHUh?=
OVCAR-8 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWrVOJFxUUN3ME2xNk4yOTRzIN88US=> M2r6fHNCVkeHUh?=
SJRH30 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV3JW5NjUUN3ME2xNk4zOjl7IN88US=> MWjTRW5ITVJ?
DMS-53 NV36Wm1oT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1\lT2lEPTB;MUKuNlY1QSEQvF2= NFHxfGdUSU6JRWK=
NCI-H322M NYrwTVNuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmfWTWM2OD1zMj6zN|U4KM7:TR?= NV7wZXBkW0GQR1XS
RVH-421 MnrpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlPKTWM2OD1zMj60PVA1KM7:TR?= Mkm2V2FPT0WU
Raji NI[ydnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkD1TWM2OD1zMj62NVQh|ryP MoraV2FPT0WU
MDA-MB-415 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlq5TWM2OD1zMj62OFQ1KM7:TR?= MWnTRW5ITVJ?
EFE-184 NF7QdHFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYTJR|UxRTF{LkexNFYh|ryP NIXPS2FUSU6JRWK=
BFTC-909 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnT3TWM2OD1zMj65NlQ4KM7:TR?= MVnTRW5ITVJ?
BHY MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIrocZJKSzVyPUGzMlM{QSEQvF2= NIP5RopUSU6JRWK=
YKG-1 Ml7wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH[0e4RKSzVyPUGzMlM4PDlizszN MkDCV2FPT0WU
EW-3 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWfUU|RnUUN3ME2xN{44OTZ|IN88US=> MmXjV2FPT0WU
HCC1143 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVHJR|UxRTF|Lke0N|ch|ryP NEPKWVlUSU6JRWK=
REH MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3\0VWlEPTB;MUOuPFk5OiEQvF2= NIDaUZBUSU6JRWK=
CESS NV\pU3FET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoLaTWM2OD1zMz65OFg6KM7:TR?= MlzzV2FPT0WU
EFM-19 M4XK[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4\pN2lEPTB;MUSuNVEyOiEQvF2= MV;TRW5ITVJ?
U031 NE\jeWFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXzReJBnUUN3ME2xOE41ODh3IN88US=> NYDzO24zW0GQR1XS
ES1 NILoSnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEP4Nm9KSzVyPUG0MlQ5PTFizszN MYfTRW5ITVJ?
HSC-3 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWnHb3lwUUN3ME2xOE43OjF3IN88US=> Ml\tV2FPT0WU
LOXIMVI MoL4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIH6fWFKSzVyPUG0MlcxPjhizszN NFvYOI1USU6JRWK=
A388 NH6wOoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnpSHQ5UUN3ME2xOE44PTV4IN88US=> Mn74V2FPT0WU
KP-N-YS MnLqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYLITGVqUUN3ME2xOE44PzNizszN NYW0UXA6W0GQR1XS
Capan-2 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF;j[FZKSzVyPUG0Mlc5PiEQvF2= NH:yNGxUSU6JRWK=
SKG-IIIa M3u3Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4rzTWlEPTB;MUSuPFg3OiEQvF2= NVT5eVRnW0GQR1XS
HEL MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFjaWWtKSzVyPUG0Mlg6QTdizszN NWPFOXgxW0GQR1XS
BEN M3;k[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHjxd4hKSzVyPUG0Mlk4PjZizszN MmHIV2FPT0WU
MC116 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3rTXmlEPTB;MUWuNVU6QSEQvF2= M1jySHNCVkeHUh?=
IGROV-1 MknTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHryPG9KSzVyPUG1MlI{OTdizszN NIfCV5JUSU6JRWK=
NCI-H1648 NGKzelhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{fvWmlEPTB;MUWuOVMxPSEQvF2= Mni3V2FPT0WU
ABC-1 M1Oyc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{\zcGlEPTB;MUWuPFA{OyEQvF2= Mlq2V2FPT0WU
EW-18 M2H2RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX3Kc|dZUUN3ME2xOU46QTd7IN88US=> MnKyV2FPT0WU
BC-3 M{XCNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHLlZ|BKSzVyPUG2MlA2PjJizszN MlLIV2FPT0WU
NCI-H1437 NVKxVWU5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1fOeGlEPTB;MU[uNFY3PyEQvF2= NX\m[4dkW0GQR1XS
SCC-15 NFKwWY5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIrFeJZKSzVyPUG2MlI5OjVizszN NHnzV4FUSU6JRWK=
TT NFPkTZRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGS4eYZKSzVyPUG2MlU5QDhizszN NVvkNmJPW0GQR1XS
KINGS-1 M3u3S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFzKO|RKSzVyPUG2MlgzPzNizszN MnrLV2FPT0WU
C32 M{TiV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NE\YbmNKSzVyPUG2Mlk4OTdizszN M37jdXNCVkeHUh?=
SBC-5 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGXGSVdKSzVyPUG3MlE1PzlizszN NF\3ZXFUSU6JRWK=
NB1 NEf0NppIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXLSSGZ5UUN3ME2xO{4{OTh6IN88US=> MmqwV2FPT0WU
EB-3 NHvldHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVvVOI9jUUN3ME2xO{42PzZizszN NWjnXIs{W0GQR1XS
NCI-H748 NGj2SIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVHJR|UxRTF5LkewN|Uh|ryP NXjJSnh4W0GQR1XS
IST-SL1 M2rLc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUf4e3NmUUN3ME2xO{44PTJ4IN88US=> Ml7TV2FPT0WU
WM-115 MnLpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWjhbJRlUUN3ME2xO{45ODh3IN88US=> NECxPVlUSU6JRWK=
NCI-H226 M1fK[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF3Q[HVKSzVyPUG3Mlk2PDZizszN NX3URWhIW0GQR1XS
CAL-33 NIHQUXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3jLV2lEPTB;MUiuNlc5OSEQvF2= MXPTRW5ITVJ?
SCC-4 NWnoV3N1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnnZTWM2OD1zOD6zNlI6KM7:TR?= MXPTRW5ITVJ?
RMG-I M4LkcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFS0UIRKSzVyPUG4MlY6PDdizszN NVL1[JByW0GQR1XS
KOSC-2 NWXuZXhtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYXzTol2UUN3ME2xPE44PzR4IN88US=> M2HIW3NCVkeHUh?=
A2058 NVT2cnBXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3HJN2lEPTB;MUiuPFI2PSEQvF2= NXLtNIZbW0GQR1XS
HCC70 NFWyVpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWLJR|UxRTF7LkO4PVQh|ryP M1jFcHNCVkeHUh?=
C2BBe1 M4PwUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1LhbmlEPTB;MUmuOFE1QCEQvF2= NHXJOYdUSU6JRWK=
NCI-H650 Mn3kS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlPKTWM2OD1zOT61PFk6KM7:TR?= M4n4bnNCVkeHUh?=
CAL-72 NES5UYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXTEWpRDUUN3ME2xPU43PzN5IN88US=> M{HPdHNCVkeHUh?=
L-363 NXmzRlZwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIj3UmZKSzVyPUKwMlAzOTJizszN NHPCeFJUSU6JRWK=
SNU-423 MlHUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoXyTWM2OD1{MD6xNFQ{KM7:TR?= MUfTRW5ITVJ?
PLC-PRF-5 M1zOeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVnJR|UxRTJyLkO5NFYh|ryP MYTTRW5ITVJ?
SW1463 NIG4[o1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYDJR|UxRTJyLkS1NlUh|ryP M1nxZ3NCVkeHUh?=
769-P MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4nlPWlEPTB;MkCuOlc3QSEQvF2= M4PxdXNCVkeHUh?=
DMS-79 NEXIU4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\yPJREUUN3ME2yNE45PDlizszN MUPTRW5ITVJ?
Saos-2 MmKwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXvJR|UxRTJyLkm1OVYh|ryP NF;XbodUSU6JRWK=
CHP-126 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUSzZ3FGUUN3ME2yNU41PDZ{IN88US=> NEDTWWVUSU6JRWK=
SW837 Ml;HS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1rRTmlEPTB;MkGuOFk{QSEQvF2= Ml\1V2FPT0WU
SHP-77 MlS5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIDRZopKSzVyPUKxMlYyOjJizszN MXjTRW5ITVJ?
DB NEm0[XhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYmxS5NoUUN3ME2yNU43OTR{IN88US=> M4PZ[XNCVkeHUh?=
ES5 NVzK[2RJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1;RT2lEPTB;MkGuOlg3PCEQvF2= NG\OZlZUSU6JRWK=
COR-L23 NGO0U2VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPaNZoyUUN3ME2yNU45ODVzIN88US=> MYrTRW5ITVJ?
KU-19-19 MkLJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIjwRXlKSzVyPUKxMlg6QDJizszN MVPTRW5ITVJ?
T84 M4PEfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnzFTWM2OD1{MT65PFE6KM7:TR?= NITNS2hUSU6JRWK=
NCI-H630 Mn60S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXjDSGNxUUN3ME2yNk42OzZ|IN88US=> M{PicHNCVkeHUh?=
LU-165 NUDvVGs4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGDRVJNKSzVyPUKyMlU2PCEQvF2= MYPTRW5ITVJ?
COLO-792 NFrlbXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4PFbGlEPTB;MkKuO|EyOSEQvF2= NG[wZoJUSU6JRWK=
CAL-62 NUPiNFNHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2rMTWlEPTB;MkKuO|UyPyEQvF2= Mmr1V2FPT0WU
HCE-T MnW3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3iwZ2lEPTB;MkKuPFYxPiEQvF2= MljDV2FPT0WU
BB65-RCC NEXxR|hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1f2fGlEPTB;MkOuNFM1PCEQvF2= MVLTRW5ITVJ?
SiHa MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUfJR|UxRTJ|LkO5Olgh|ryP M1OwcHNCVkeHUh?=
NCI-H2081 NI\ncZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2XhNGlEPTB;MkSuNFY1OSEQvF2= M3L4UXNCVkeHUh?=
U251 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVnJR|UxRTJ2LkC2Olgh|ryP MV7TRW5ITVJ?
LoVo NWPvSYRjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnfITWM2OD1{ND65NlgzKM7:TR?= NYfVc5hlW0GQR1XS
GCIY MlLoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV7qVoJoUUN3ME2yOU4zQDd5IN88US=> M2LvR3NCVkeHUh?=
NUGC-3 NWDGRm5RT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIfkdZlKSzVyPUK1MlM{OTZizszN M1PwbnNCVkeHUh?=
LNCaP-Clone-FGC NYThb4VjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVfJR|UxRTJ3LkO0PVgh|ryP MV3TRW5ITVJ?
PA-1 M2mzOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYXDXmZwUUN3ME2yOU43QDN|IN88US=> NIjkZZdUSU6JRWK=
OE33 M1LiNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4LSdWlEPTB;MkWuOlg2OyEQvF2= M3r2SnNCVkeHUh?=
HT-29 Mk[wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUSxS|NZUUN3ME2yOU44QDd7IN88US=> NU\HbmVpW0GQR1XS
RCM-1 M1fYemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGi2b4pKSzVyPUK1Mlk3PTZizszN MmqxV2FPT0WU
NCI-H1522 MoTpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnHkTWM2OD1{NT65PVEyKM7:TR?= NFPpZ49USU6JRWK=
LB373-MEL-D NV60[XM{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2C1S2lEPTB;Mk[uNVcxQCEQvF2= M2jSPHNCVkeHUh?=
NCI-H1436 M1fLfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV3tOGdzUUN3ME2yOk4zPzN6IN88US=> MnXwV2FPT0WU
COLO-824 NVzxOXBWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVnJR|UxRTJ4LkSwNFIh|ryP MUPTRW5ITVJ?
CP50-MEL-B NIfMZWpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3r5[mlEPTB;Mk[uOVY4PSEQvF2= M2LTfHNCVkeHUh?=
EGI-1 M2G4bWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUDJR|UxRTJ5LkK2PVgh|ryP NI[4bo5USU6JRWK=
LAN-6 NFvGUXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXvJR|UxRTJ5LkO1PVgh|ryP NH6xSZZUSU6JRWK=
GAK M16xW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHfTVIFKSzVyPUK3MlQzOjVizszN MW\TRW5ITVJ?
MDA-MB-175-VII NHjUV2tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV7JR|UxRTJ5LkWwOVMh|ryP MmXGV2FPT0WU
JVM-2 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MW\JR|UxRTJ5Lk[2NlIh|ryP MWfTRW5ITVJ?
UACC-257 MmPIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYTTeol1UUN3ME2yO{43QDd6IN88US=> MoPyV2FPT0WU
SW1783 NEjpRYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnXHTWM2OD1{Nz63O|g{KM7:TR?= NHvOc5NUSU6JRWK=
HT-3 Moe0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mof2TWM2OD1{OD6yNVY3KM7:TR?= NVfrWZhMW0GQR1XS
RL M2DaTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHHWWJhKSzVyPUK4MlU6OTFizszN MorPV2FPT0WU
TK10 Mmm3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV;4fnc2UUN3ME2yPE43PTN3IN88US=> M1X5bHNCVkeHUh?=
HT55 MmPpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4ew[2lEPTB;MkmuNFU3PSEQvF2= MnfQV2FPT0WU
BT-20 NELiT2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NETvbJpKSzVyPUK5MlA2QDZizszN NXf5WIozW0GQR1XS
TGBC24TKB MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXXQWVFqUUN3ME2yPU4yQDNzIN88US=> NHXufGJUSU6JRWK=
HSC-2 MlLpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmToTWM2OD1{OT6zNFAyKM7:TR?= MlvYV2FPT0WU
COLO-205 NXLyO2pyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH3mZ4pKSzVyPUK5MlM6PDRizszN MW\TRW5ITVJ?
GT3TKB M4\qVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVHJR|UxRTJ7Lk[4O|ch|ryP M33s[HNCVkeHUh?=
T47D NVr1WW9zT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkDXTWM2OD1{OT64OVgzKM7:TR?= MnLCV2FPT0WU
OMC-1 M4DETGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFnjb|FKSzVyPUOwMlE6OTlizszN NWLmWIhxW0GQR1XS
PFSK-1 NVHteG96T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M13ubmlEPTB;M{GuNlY2QSEQvF2= M3PQWXNCVkeHUh?=
JEG-3 M{jMfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmH1TWM2OD1|MT6zOVYyKM7:TR?= M3HRTHNCVkeHUh?=
RD MkXSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1z1T2lEPTB;M{GuOVEyPSEQvF2= NHnFdohUSU6JRWK=
NCI-H64 Ml60S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV7COG9XUUN3ME2zNk41OTd7IN88US=> NGHDfZNUSU6JRWK=
DMS-114 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnXiTWM2OD1|Mj60NVgzKM7:TR?= MoTIV2FPT0WU
NCI-H661 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVXJR|UxRTN{Lk[1NFEh|ryP MmjRV2FPT0WU
CAL-148 NHLB[2VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjOTWM2OD1|Mj62OlY2KM7:TR?= MVrTRW5ITVJ?
HuP-T3 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUTpb4xtUUN3ME2zNk46OzN6IN88US=> NULkWIhJW0GQR1XS
ES4 NYjZXodJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEH1ZoVKSzVyPUOzMlE4ODVizszN NIr3VnBUSU6JRWK=
Ca9-22 NYO2OJpbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoPITWM2OD1|Mz60OlAyKM7:TR?= NGTHPGhUSU6JRWK=
LP-1 M3T2UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX74TnlLUUN3ME2zOE4xQSEQvF2= MnS1V2FPT0WU
AU565 MnHtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXHJR|UxRTN2LkWwOlkh|ryP M4q5dXNCVkeHUh?=
MDA-MB-453 Ml7FS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1HvPWlEPTB;M{WuNVQzPiEQvF2= MWLTRW5ITVJ?
SNU-C1 MkjFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEWze4JKSzVyPUO1MlE4OSEQvF2= NWCwU4FCW0GQR1XS
SW13 NGTYU4ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUnnN4pbUUN3ME2zOU41ODd4IN88US=> NUTWOIJ5W0GQR1XS
NCI-H2122 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGHvdIhKSzVyPUO1MlU2QThizszN NXjDTIVFW0GQR1XS
NCI-H1395 NIfZNGtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NELRSJBKSzVyPUO1MlY3QTFizszN MkXSV2FPT0WU
J-RT3-T3-5 NFnxTGxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWjJR|UxRTN4LkCyPVQh|ryP MVzTRW5ITVJ?
COR-L279 MkTuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml3CTWM2OD1|Nj6xPVgyKM7:TR?= MWrTRW5ITVJ?
ATN-1 M1HmXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGSxXpBKSzVyPUO2Mlg2OTZizszN MXLTRW5ITVJ?
HCC2998 NIDsU2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXTtTIhZUUN3ME2zOk45PTdzIN88US=> MnfkV2FPT0WU
UM-UC-3 NVfjS3U3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFmyW5FKSzVyPUO2Mlg3PzVizszN NHjGWmNUSU6JRWK=
DV-90 NIjqNoRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIjnOIVKSzVyPUO2MlkxPjdizszN M1TvXHNCVkeHUh?=
ES8 NVvOU|VnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVrJR|UxRTN4LkmzNVgh|ryP MlXtV2FPT0WU
YAPC NHjEelJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVnJR|UxRTN4Lkm2OVQh|ryP MXnTRW5ITVJ?
HCC1599 NE\jXGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEjWcVZKSzVyPUO3MlE3OThizszN NYDPSpFYW0GQR1XS
UMC-11 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUPJR|UxRTN5LkK1NFMh|ryP M3vh[3NCVkeHUh?=
THP-1 M4DaSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnHVTWM2OD1|Nz6yPFY5KM7:TR?= NFyyOGRUSU6JRWK=
OCUB-M M2q1eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3HtSWlEPTB;M{euNlg6OSEQvF2= NVj6S3pLW0GQR1XS
NCI-H1693 NVz3W5ZtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWjSW49rUUN3ME2zO{4{OjN|IN88US=> MlHzV2FPT0WU
NCI-H345 MkLUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkfoTWM2OD1|Nz6zOlI1KM7:TR?= MV7TRW5ITVJ?
COLO-800 NFvSeIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEHsempKSzVyPUO3MlU3PyEQvF2= NFnNcJVUSU6JRWK=
COLO-320-HSR NW\XSFhHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWHnepk3UUN3ME2zPE4{PDl{IN88US=> NETEPWhUSU6JRWK=
NCI-H596 M{fkT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIrrfGRKSzVyPUO4MlQ1QDlizszN MlzYV2FPT0WU
NCI-H187 M37ofGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX7kdFhSUUN3ME2zPE44OzR2IN88US=> M325O3NCVkeHUh?=
ECC4 NX3melZZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4THcGlEPTB;M{muNFgyPCEQvF2= MVfTRW5ITVJ?
KP-4 NGKxSIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV3JR|UxRTN7LkGyN|Uh|ryP M{nifXNCVkeHUh?=
NCI-H2227 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV7LbGJUUUN3ME2zPU4{QTR7IN88US=> M3ixZ3NCVkeHUh?=
22RV1 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NELidnVKSzVyPUO5Mlg{QThizszN NHrhUXVUSU6JRWK=
SAS MlvTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1HhcWlEPTB;NECuNFk3KM7:TR?= NGDWS45USU6JRWK=
PANC-10-05 M1fBZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M175U2lEPTB;NECuNVgzQCEQvF2= NHv4Z|BUSU6JRWK=
MDA-MB-468 NFPENWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlS4TWM2OD12MD61N|Q3KM7:TR?= M4fwW3NCVkeHUh?=
RPMI-7951 NXHwemlbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4K1dmlEPTB;NEGuNlA4PSEQvF2= NVXrdZhOW0GQR1XS
BB49-HNC MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUHPe4s6UUN3ME20NU4zOTd7IN88US=> MlK1V2FPT0WU
23132-87 NV\IV44yT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX\4fZZjUUN3ME20NU4zPzN{IN88US=> M{HmbHNCVkeHUh?=
HCC1569 NG[4dodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUjJR|UxRTRzLkK4PFUh|ryP M1XhPXNCVkeHUh?=
CP66-MEL M{XBUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYDNTYNrUUN3ME20Nk4yQDh4IN88US=> Mlv1V2FPT0WU
K-562 Mo\mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NU\ycnE3UUN3ME20Nk4zQDV2IN88US=> MYPTRW5ITVJ?
OCI-AML2 M1zxdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWjJR|UxRTR{Lki5O|Qh|ryP NU\rdo5ZW0GQR1XS
SW756 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnnOTWM2OD12Mz6wN|g5KM7:TR?= MWjTRW5ITVJ?
M14 NY\EXpYxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1f1eGlEPTB;NEOuN|E5QSEQvF2= NUK2TGlDW0GQR1XS
NCI-H1623 NYOxVGZNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1jCfWlEPTB;NEOuOFY1KM7:TR?= NXn1bplpW0GQR1XS
KNS-81-FD MmqzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVTJR|UxRTR|Lke2NkDPxE1? MXPTRW5ITVJ?
TGBC1TKB MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTR|LkmwPVkh|ryP NHLKOXdUSU6JRWK=
RERF-LC-MS NX3RRmNxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWLudWNTUUN3ME20N{46OjhzIN88US=> NX36N3JFW0GQR1XS
PC-3 NYjrSW5iT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX:yTVNrUUN3ME20OE41OzR5IN88US=> MX;TRW5ITVJ?
HuP-T4 NVHqS3lUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUnJR2Q3UUN3ME20OE41PDd2IN88US=> MXTTRW5ITVJ?
NCI-H510A NYG4UHdZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnHGTWM2OD12ND63NFgh|ryP MYHTRW5ITVJ?
LB2518-MEL M1;6cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGn1NppKSzVyPUS0Mlc6OzdizszN Mn7pV2FPT0WU
TE-5 M3jicGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MorqTWM2OD12NT65OVgyKM7:TR?= NF:1PYRUSU6JRWK=
EW-24 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlvmTWM2OD12Nj6xO|I{KM7:TR?= Mn7KV2FPT0WU
LB647-SCLC NXTJOmY4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1zlbGlEPTB;NE[uNlE2PSEQvF2= MkT0V2FPT0WU
NCI-H524 M3nWOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVHJR|UxRTR4LkexPFUh|ryP M{Tsb3NCVkeHUh?=
EW-11 M1\MeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWW0NYY3UUN3ME20Ok46Ozd|IN88US=> NVTMTYtqW0GQR1XS
KALS-1 NXXNXnFMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUDJR|UxRTR5LkKwOlYh|ryP MXPTRW5ITVJ?
BT-474 MnvtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUjr[nhyUUN3ME20O{41OjF4IN88US=> MX7TRW5ITVJ?
SK-N-AS NEP5e5hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIO0Zm9KSzVyPUS3Mlg5QCEQvF2= NVL5WmJLW0GQR1XS
HCC2157 M1LNcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVvZSXNWUUN3ME20PE4xPzZizszN M2HUcnNCVkeHUh?=
HCC1954 M2jjd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXuxfW9OUUN3ME20PE4yPzB2IN88US=> NXrwVlVjW0GQR1XS
FADU MlL3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlXmTWM2OD12OD6zNFMyKM7:TR?= MkHlV2FPT0WU
S-117 NETpVHRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXnJR|UxRTR6LkO4NVUh|ryP NWLPcIptW0GQR1XS
LS-1034 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV7JR|UxRTR6LkewOlch|ryP MmPpV2FPT0WU
CAMA-1 Mo\JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYC3UndVUUN3ME20PU42PTR|IN88US=> MmixV2FPT0WU
LU-134-A Mmq4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnJRVlKSzVyPUS5MlgxQDVizszN MUTTRW5ITVJ?
NCI-H1838 MkXLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4T2b2lEPTB;NEmuPFA5PyEQvF2= MlLIV2FPT0WU

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
pSrc / Src / pPlcg / Plcg / pStat5 / Stat5 ; 

PubMed: 22781593     


In (B) inhibition of Src, Plcg and Stat5 was seen in MLNAF cell lines treated with Ponatinib; ZNF112 expresses ZMYM2–FGFR1, CEP2A and CEP5A cells express CEP110–FGFR1 and BBC2 expresses BCR–FGFR1.

pFGFR1(pY20) / FGFR1; 

PubMed: 22781593     


Western blot analysis, using various antibodies specific for downstream targets of FGFR1, demonstrates that Ponatinib inhibits the activation of Plcg and Src as a result of inhibiting the FGFR1 fusion kinase in human KG1 cells. 

cleaved caspase-3 / cleaved caspase-7 / BAX / Bcl-2; 

PubMed: 30959969     


Western blot analysis of cleaved caspase-3, cleaved caspase-7, Bax, Bcl-2, and β-Tubulin (control) in treated cells.

p-Rb(S807/811) / Rb / CDK4 / CDK6 / Cyclin D1 / CDK2 / Cyclin E1; 

PubMed: 30959969     


Western blot analysis of Rb/p-Rb, CDK4, CDK6, Cyclin D1, CDK2, Cyclin E1, and β-Tubulin (control) in the SK-Hep-1 and SNU-423 cells treated with ponatinib. 

RAD51; 

PubMed: 30959969     


The effect of ponatinib on the concentration of Rad51 in SK-Hep-1 and SNU-423 cells.

p-MEK / MEK / p-ERK / ERK; 

PubMed: 30959969     


Effect of ponatinib on the phosphorylation of Mek and Erk. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was used as a control.

c-Jun / p-JNK(T183/Y185) / JNK; 

PubMed: 30959969     


Effect of ponatinib on the phosphorylation of JNK and c-Jun. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was used as a control.

p-p38 MAPK / p38 MAPK; 

PubMed: 30959969     


Effect of ponatinib on the phosphorylation of p38. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was used as a control.

p-JAK2 / JAK2 / p-STAT3 / STAT3; 

PubMed: 30959969     


Effect of ponatinib on the phosphorylation of Jak2, and Stat3. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was used as a control.

PI3K p85 / p-PI3K / p-PDK1 / PDK1 / p-mTOR / mTOR; 

PubMed: 30959969     


Effects of ponatinib on the protein concentration and phosphorylation of PI 3-kinase, PDK1, Akt, and mTOR in HCC cells. 

p-PDGFRα / PDGFRα; 

PubMed: 24472312     


Ponatinib inhibited phosphorylation of PDGFRα in a concentration-dependent manner. EOL-1 and BaF3-WT or -T674I FIP1L1-PDGFRα cells were exposed to escalating concentrations of ponatinib for 24 h.

PARP / Caspase-3 / Active Caspase-3; 

PubMed: 24472312     


The concentration- (for 24 h) and time-dependent (1 nM for EOL-1, 300 nM for BaF3-WT and -T674I FIP1L1-PDGFRα cells) cleavage of PARP and caspase-3 triggered by ponatinib was analyzed by immunoblotting.

AIF / Cyto C ; 

PubMed: 24472312     


Ponatinib elicited release of AIF and cytochrome c into the cytosol. Cells were treated with 1 nM ponatinib for the indicated durations and the cytosolic fraction was extracted with digitonin buffer. Levels of AIF and Cytochrome c (Cyto c) were detected by immunoblotting.

Mcl-1 / Survivin / Bcl-Xl / XIAP / Bax / Bcl-2 / Bim; 

PubMed: 24472312     


Immunoblotting of apoptosis-related proteins in CEL cells after treatment for 24 h.

β-catenin ; 

PubMed: 24472312     


Ponatinib concentration-dependently lowered β-catenin. EOL-1 cells were incubated with ponatinib for 24 h, and cytoplasmic and nuclear extracts were determined by immunoblotting.

β-catenin; 

PubMed: 24472312     


Analysis of β-catenin localization. EOL-1 cells were pretreated with 1 nM ponatinib for 24 h, immunofluorescence analysis was performed with anti-β-catenin. Nuclei were stained with 4,6-diamidino-2-phenylindole (DAPI). 

ABL; 

PubMed: 19878872     


In vitro [γ-32P]-ATP autophosphorylation of full-length (A) ABL or (B) ABLT315I kinase treated with AP24534, imatinib, nilotinib, or dasatinib. After incubation of tyrosine-dephosphorylated enzyme with the indicated inhibitor in the presence of [γ-32P]-ATP and separation by SDS-PAGE, signal intensity was measured by autoradiography.

22781593 30959969 24472312 19878872
Growth inhibition assay
Cell viability; 

PubMed: 30174789     


(A) Effect of Ponatinib on basal viability of HUVECs. The cells were treated with Ponatinib at indicated concentrations or 0.1% DMSO (vehicle control) for 24 h.

30174789
In vivo In a mouse xenograft model of Ba/F3 cells expressing native Bcr-Abl, AP24534 (2.5 mg/kg and 5 mg/kg) prolongs mice median survival. In the xenograft model of Ba/F3 Bcr-AblT315I, AP24534 (10 mg/kg–50 mg/kg) significantly suppresses tumor growth. AP24534 (30 mg/kg) decreases the phosphorylated Bcr-Abl and phosphorylated CrkL levels in the tumors. [2]

Protocol

Kinase Assay:[1]
- Collapse

Peptide substrate phosphorylation assays with GST-Abl kinase domains:

The effect of AP24534 (0-320 nM) on GST-Abl kinase activity is assessed by using a synthetic peptide substrate (Abltide: EAIYAAPFAKKK). Assays are carried out at 30 °C for 15 min in 25 μL reaction mixture: 8 mM MOPS (pH 7), 0.2 mM EDTA, 50 μM Abltide, 30 mM MgCl2, 10 mM β-glycerol phosphate, 1 mM EGTA, 0.002% Brij-35, 0.4 mM DTT, 0.2 mg/mL BSA, 0.4 mM sodium orthovanadate, 10 nM WT or mutant GST-Abl kinase, and 100 µM ATP/γ-32[P]ATP (5000 cpm/pmol). Reactions are terminated by transferring a portion of the reaction mixture onto a p81 phosphocellulose filter and immersing in 0.75% phosphoric acid. Filters are washed 3 times in 0.75% phosphoric acid, rinsed in acetone, and air dried; phosphate incorporation is determined by scintillation counting. All results are corrected for background binding to the filters, as determined by omitting peptide substrate from the kinase reaction. Time course experiments to establish the linear range of enzymatic activity precedes kinase assays.
Cell Research:[2]
- Collapse
  • Cell lines: Ba/F3 cells expressing Bcr-Abl or a range of single mutations in the kinase domain of Bcr-Abl
  • Concentrations: 0-625 nM
  • Incubation Time: 72 hours
  • Method: Ba/F3 cell lines are distributed in 96-well plates (4 × 103 cells/well) and incubated with AP24534 for 72 hours. Proliferation is measured using a methanethiosulfonate (MTS)-based viability assay (CellTiter96 Aqueous One Solution). All values are normalized to the control wells with no drug. IC50 values are reported as the mean of three independent experiments performed in quadruplicat
    (Only for Reference)
Animal Research:[1]
- Collapse
  • Animal Models: Mouse xenograft models of Ba/F3 cells expressing Bcr-Abl or Bcr-AblT315I
  • Formulation: Dissolved in 25 mM citrate buffer, pH 2.75
  • Dosages: 2.5 mg/kg and 5 mg/kg for Ba/F3 Bcr-Abl; 2.5 mg/kg–50 mg/kg for Ba/F3 Bcr-AblT315I
  • Administration: Oral gavage once daily
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 30 mg/mL (56.33 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
1% CMC Na
For best results, use promptly after mixing.
30mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 532.56
Formula

C29H27F3N6O

CAS No. 943319-70-8
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04070443 Not yet recruiting Drug: Ponatinib|Drug: Imatinib Philadelphia Chromosome Positive CML|BCR-ABL Positive Chronic Myelogenous Leukemia Centre Leon Berard October 1 2019 Phase 2
NCT03934372 Not yet recruiting Drug: Ponatinib Acute Myeloid Leukemia|Accelerated Phase Chronic Myeloid Leukemia|Blast Phase Chronic Myeloid Leukemia|Chronic Phase Chronic Myeloid Leukemia|Acute Lymphoblastic Leukemia|Acute Lymphocytic Leukemia|Leukemia|Lymphoma|Solid Tumors Incyte Biosciences International Sàrl|Incyte Corporation October 25 2019 Phase 1|Phase 2
NCT03895671 Recruiting Drug: Ponatinib|Drug: Azacitidine CHRONIC MYELOGENOUS LEUKAEMIA IN ACCELERATED PHASE|CHRONIC MYELOGENOUS LEUKAEMIA IN MYELOID BLAST CRISIS Versailles Hospital June 19 2019 Phase 2
NCT03690115 Recruiting Drug: Ponatinib 30 MG Leukemia Myeloid Acute Versailles Hospital December 12 2018 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    Is the pre-solubilized inhibitor suitable for in vivo whole animal studies? Whether the solvent contains any non-DMSO stabilizer?

  • Answer:

    Our 10mM Ponatinib in DMSO solution is in pure DMSO and there is not other stabilizer added. You can use it for animal study. The vehicle we suggest for Ponatinib is: 30% PEG400/0.5% Tween80/5% Propylene glycol. It is a milky suspension used for oral gavage.

Bcr-Abl Signaling Pathway Map

Bcr-Abl Inhibitors with Unique Features

Related Bcr-Abl Products

Tags: buy Ponatinib (AP24534) | Ponatinib (AP24534) supplier | purchase Ponatinib (AP24534) | Ponatinib (AP24534) cost | Ponatinib (AP24534) manufacturer | order Ponatinib (AP24534) | Ponatinib (AP24534) distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID