Photosensitizer

Other Apoptosis Related Inhibitors

Caspase Bcl-2 p53 Ferroptosis PD-1/PD-L1 Survivin TNF-alpha MDM2/MDMX KRas IAP

Cat.No.	Product Name	Information	Product Use Citations
S1786	Verteporfin	Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin. Verteporfin is an autophagy inhibitor. Verteporfin inhibits cell proliferation and induces apoptosis.	Nat Commun, 2025, 16(1):4124 Adv Sci (Weinh), 2025, 12(44):e11726 Cell Death Differ, 2025, 10.1038/s41418-025-01446-2
E8123	Methyl pyropheophorbide-a	Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth.
S9911	Chlorin e6	Chlorin e6(Ce6, Phytochlorin) is a photosensitizer characterized by strong absorption peaks at 402 nm and 662 nm and intense fluorescence at 668 nm. It possesses antimicrobial and anticancer activities. It activates caspase-3 and induces apoptosis in cells, making it valuable for cancer research.Solutions are unstable and should be fresh-prepared.
E7081	Purpurin 18	Purpurin-18 is a chlorophyll-derived dihydroporphyrin, serves as a key precursor for photosensitizers like purpurinimides, which absorb light in the 700–850 nm range. It demonstrate potent photodynamic anti-tumor activity and generates ROS, disrupting mitochondrial membrane potential and inducing apoptosis against triple-negative breast cancer both in vitro and in vivo.
S1750	Octocrylene	Octocrylene is an organic compound used as an ingredient in sunscreens and cosmetics.
E8055	Hematoporphyrin monomethyl ether	Hematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and research of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma.
S4552	Bithionol	Bithionol (Actamer) is a potent inhibitor of soluble adenylyl cyclase(sAC) with an IC50 of 4 μM and has antibacterial and anthelmintic properties along with algaecide activity.	iScience, 2023, 10.1016/j.isci.2023.106661 Cancer Lett, 2020, 479:100-111 Inflammation, 2019, 42(5):1530-1541