Photosensitizer

Other Apoptosis Related Inhibitors

Caspase Bcl-2 p53 Ferroptosis PD-1/PD-L1 Survivin TNF-alpha MDM2/MDMX KRas IAP

Cat.No.	Product Name	Information	Product Use Citations
S1786	Verteporfin	Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin. Verteporfin is an autophagy inhibitor. Verteporfin inhibits cell proliferation and induces apoptosis.	Theranostics, 2026 Jan 1, 2372-2387 Theranostics, 2026, 2372-2387 Cell Death Dis, 2026, 10.1038/s41419-026-08574-8
S9911	Chlorin e6	Chlorin e6(Ce6, Phytochlorin) is a photosensitizer characterized by strong absorption peaks at 402 nm and 662 nm and intense fluorescence at 668 nm. It possesses antimicrobial and anticancer activities. It activates caspase-3 and induces apoptosis in cells, making it valuable for cancer research.Solutions are unstable and should be fresh-prepared.
E7081	Purpurin 18	Purpurin-18 is a chlorophyll-derived dihydroporphyrin, serves as a key precursor for photosensitizers like purpurinimides, which absorb light in the 700–850 nm range. It demonstrate potent photodynamic anti-tumor activity and generates ROS, disrupting mitochondrial membrane potential and inducing apoptosis against triple-negative breast cancer both in vitro and in vivo.
S1750	Octocrylene	Octocrylene is an organic compound used as an ingredient in sunscreens and cosmetics.
S4552	Bithionol	Bithionol (Actamer) is a potent inhibitor of soluble adenylyl cyclase(sAC) with an IC50 of 4 μM and has antibacterial and anthelmintic properties along with algaecide activity.	iScience, 2023, 10.1016/j.isci.2023.106661 Cancer Lett, 2020, 479:100-111 Inflammation, 2019, 42(5):1530-1541