Home Metabolism Phosphorylase

Phosphorylase

Other Metabolism Related Inhibitors

Dehydrogenase Transferase DPP Aminopeptidase Procollagen C Proteinase P450 (e.g. CYP17) Phospholipase (e.g. PLA) Factor Xa PDE DHFR
Cat.No. Product Name Information Product Use Citations Product Validations
S2717 CP-91149 CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.
Nat Commun, 2024, 15(1):1524
EMBO Rep, 2024, 10.1038/s44319-024-00278-4
Cell Rep, 2023, 42(6):112578
Verified customer review of CP-91149
S2045 Doxifluridine Doxifluridine (5'-DFUR, AMC 0101) is an oral prodrug that is converted to the cytotoxic agent 5-fluorouracil (5-FU).
BIOCHIP J, 2023, 17, 284–292
Acta Histochem, 2022, 124(4):151895
Cell Metab, 2019, 29(5):1217-1231
S3731 Tipiracil hydrochloride Tipiracil (MA-1) is an inhibitor of thymidine phosphorylase, the enzyme that degrades trifluridine into trifluorothymidine. Its combination with trifluridine increases the bioavailability of trifluridine.
iScience, 2024, 27(10):110862
Cell Mol Immunol, 2022, 10.1038/s41423-022-00842-9
JCI Insight, 2022, 7(22e158060)
S0031 Ingliforib Ingliforib (CP 368296) is a glycogen phosphorylase (GP) inhibitor, with IC50s of 52, 352 and 150 nM for liver, muscle and brain glycogen phosphorylase, and has cardioprotective activity.
S6510 Iso-H7 dihydrochloride Iso-H7 dihydrochloride is an inhibitor of phosphokinase C.
E6031 Tipiracil Tipiracil is a thymidine phosphorylase (TPase) inhibitor.