Phosphorylase

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S2717 CP-91149 <1 mg/mL 80 mg/mL <1 mg/mL
S3731 Tipiracil hydrochloride 55 mg/mL 8 mg/mL <1 mg/mL
S2045 Doxifluridine 49 mg/mL 49 mg/mL <1 mg/mL
Catalog No. Information Product Use Citations Product Validations
S2717

CP-91149

CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.

S3731New

Tipiracil hydrochloride

Tipiracil is an inhibitor of thymidine phosphorylase, the enzyme that degrades trifluridine into trifluorothymidine. Its combination with trifluridine increases the bioavailability of trifluridine.

S2045

Doxifluridine

Doxifluridine is an oral prodrug that is converted to the cytotoxic agent 5-fluorouracil (5-FU).