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S9354
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Oxalic acid
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Oxalic acid (Ethanedioic acid, Wood bleach) is a strong dicarboxylic acid occurring in many plants and vegetables.
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S5636
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Methyl furan-2-carboxylate
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Methyl furan-2-carboxylate (Methyl pyromucate, Methyl 2-furoate) is found in cocoa and cocoa products. It is used in food flavouring and preparation of sesquiterpene lactone.
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S3814
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Tubeimoside I
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Tubeimoside I (Lobatoside H, TBMS1), a triterpenoid saponin, isolated from the tubers of Bolbostemma paniculatum, shows potent antitumor and antitumor-promoting effects.
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S8068
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Chaetocin
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Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR).
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S3790
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Methyl gallate
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Methyl Gallate (Methylgallate, Gallic acid methyl ester, Gallicin) is a plant polyphenol with antioxidant, anticancer, and anti-inflammatory activities.
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S4800
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Daminozide
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Daminozide (Aminozide, DMASA, DIMG, B 995, Alar, Kylar, B-NINE, SADH) is a plant growth regulator that selectively inhibits human KDM2/7 histone demethylases, with IC50 of 0.55 μM for PHF8 (KDM7B), 1.5 μM for KDM2A, and 2.1 μM for KIAA1718 (KDM7A). It shows over 100-fold selectivity for the KDM2/7 subfamily compared to other histone demethylase subfamilies, with significantly weaker activity against enzymes such as KDM3A with IC50 of 127 μM.
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S9188
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Magnoflorine chloride
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Magnoflorine (Escholine, Thalictrine, Corytuberine methochloride), isolated from the rhizome of Sinomenium acutum and from Pachygone ovata, is usually used as an anxiolytic chemical with anti-oxidant, α-tyrosinase inhibitory and anti-inflammationary activities.
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S9189
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Oroxin A
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Oroxin A (Baicalein 7-O-glucoside), an active component isolated from the herb Oroxylum indicum (L.) Kurz, activates PPARγ and inhibits α-glucosidase, exerting antioxidant activity.
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S9190
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Oroxin B
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Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. This compound significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, it potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after this chemical treatment.
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S9191
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Loganic acid
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Loganic acid (Loganate) is a naturally occurring iridoid monoterpeneglusoside involved in the biosynthesis of indole alkaloids in Vinca rosea.
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S9194
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Toddalolactone
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Toddalolactone, a natural coumarin, inhibits the activity of recombinant human Plasminogen activator inhibitor-1 (PAI-1) in a dose-dependent manner, yielding an IC50 value of 37.31 ± 3.23 μM.
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S9195
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Maltotetraose
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Maltotetraose, found in many foods, belongs to the class of organic compounds known as oligosaccharides.
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S9196
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Calceolarioside B
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Calceolarioside B (Nuomioside A), found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property. This compound exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC50 of 23.99 μM. It also displays inhibitory effect on DPPH radical scavenging activity with an IC50 of 94.60 μM.
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S9199
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Pseudoginsenoside F11
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Pseudoginsenoside F11, a natural product found in American ginseng but not in Asian ginseng, is a novel partial PPARγ agonist.
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S9200
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Pneumocandin B0
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Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
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S9203
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Notopterol
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Notopterol is a kind of furanocoumarin that possesses anti-inflammatory, analgesic, and anticancer activities.
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S9204
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Oroxylin A
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Oroxylin A (6-Methoxybaicalein) is a flavonoid isolated from Scutellaria root that exhibits multiple pharmacological activities, including anti-oxidative, anti-inflammatory, anti-viral and anti-tumor properties.
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S9205
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Hydroxygenkwanin
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Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, has anti-oxidant ability and can act as tissue factor (TF) inhibitor to prevent thrombosis. This compound, a natural flavonoid compound, has anti-oxidant ability and can act as tissue factor (TF) inhibitor to prevent thrombosis.
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S9206
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Hydroprotopine
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Hydroprotopine (W1171) is a kind of natural herbal extract.
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S9514
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Rotundic acid
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Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.RA induces cell cycle arrest, DNA damage, and apoptosis by modulating the AKT/mTOR and MAPK pathways.
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