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S9052
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Auraptene
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Auraptene (7-geranyloxycoumarin) is a natural coumarin derived from citrus plants and possesses valuable pharmacological properties, including anticarcinogenic, anti-inflammatory, antihelicobacter, antigenotoxic, and neuroprotective effects. This compound inhibits matrix metalloproteinase 2 (MMP-2) as well as key inflammatory mediators, including IL-6, IL-8 and chemokine (C-C motif) ligand-5(CCL5).
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S9045
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Triptophenolide
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Triptophenolide (Hypolide), derived from Tripterygium wilfordii, is a pan-antagonist for wild-type and mutant androgen receptors with the IC50 values of 260 nM for AR-WT, 480 nM for AR-F876L, 388 nM for AR-T877A, and 437 nM for W741C+T877A.
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S9061
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Hydroxy safflor yellow A
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Hydroxy safflor yellow A, a monomer extracted from Carthamus tinctorius L., possesses various kinds of bio-activities, including anti-oxidation, anti-inflammatory actions, anti-platelet aggregation, anti-tumor and anti-myocardial injury effects.
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S9062
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4-Hydroxyisoleucine
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4-Hydroxyisoleucine, an atypical branched-chain amino acid derived from fenugreek, has effects on the glucose and lipid metabolism, stimulates glucose-dependent insulin secretion and reduces insulin resistance in muscle and/or liver.
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S9063
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Harringtonine
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Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.
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S9064
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Trilobatin
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Trilobatin (P-Phlorizin), a natural flavonoid lipid molecule, is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and exihibits anti-oxidant and anti-inflammatory effect.
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S9065
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Songorine
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Songorine, a ubiquitous alkaloid in the genus Aconitum, is a novel antagonist of the GABAA receptor in rat brain and has antiarrhythmic, antinociceptive, anti-inflammatory, regenerative and CNS-modulating properties.
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S9066
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Specnuezhenide
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Specnuezhenide (Nuezhenide), one of the main ingredients of Chinese medicine, has anti-angiogenic and vision improvement effects.
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S9067
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Pseudoprotodioscin
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Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. This compound inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
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S9068
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Trillin
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Trillin (Disogluside, Diosgenin glucoside) is an active ingredient isolated from Trillium tschonoshii Maxim and acts as a potential anti-inflammatory drug for chronic hepatic inflammation.
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S9069
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Jatrorrhizine chloride
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Jatrorrhizine chloride (Neprotine, Yatrorhizine) is the hydrochloride salt form of jatrorrhizine, which is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
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S9070
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(2S)-(-)-isoxanthohumol
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(2S)-(-)-isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
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S9072
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Sweroside
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Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
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S9073
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Lithospermoside
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Lithospermoside (Griffonin), extracted from the roots of Lithospermum purpurocaeruleum and L.officinale (Borginaceae), and Thalictrum rugosum and T. dasycarpum (Ranunculaceae), has anti-oxidant, anti-tumor promoting activities.
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S9074
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Buddlejasaponin IVb
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Buddlejasaponin IVb (Saikosaponin 1b), a major component of Pleurospermum kamtschaticum, exerts anti-inflammatory and cytotoxic effects against cancer cells.
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S9075
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Mulberroside A
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Mulberroside A, isolated from the ethanol extract of Morus alba roots, is widely employed as an active ingredient in cosmetic products due to its anti-tyrosinase and anti-oxidant activities. This compound decreases the expressions of TNF-α, IL-1β and IL-6 and inhibits the activation of NALP3, caspase-1 and NF-κB and the phosphorylation of ERK, JNK and p38.
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S9076
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Typhaneoside
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Typhaneoside is a flavonoid glycoside plant extract that has an inhibitory effect on the proliferation of human umbilical arterial smooth muscle cell(HUASMC).
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S9077
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Plantamajoside
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Plantamajoside (Y0160, C10485), a hydroxycinnamic acid, is used as a biomarker in chemotaxonomical studies, and is a compound with numerous biological applications and considerable pharmacological potential.
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S9078
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Epigoitrin
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Epigoitrin (Goitrin, BA-51-090278), the main bioactive constituent of Radix isatidis, exerts antiviral, anticancer, and antithyroid activities.
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S9079
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Ginsenoside Rb2
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Ginsenoside Rb2 (Ginsenoside C) is a ginsenoside found in Panax ginseng that has a role as a plant metabolite, an antiviral agent and a hypoglycemic agent.
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