MRP Inhibitors

Cat.No.	Product Name	Information	Product Use Citations
S8126	MK-571 (L-660711)	MK571 is a selective, orally active CysLT1 receptor(Cysteinyl leukotriene receptor) antagonist.	Nat Commun, 2025, 16(1):6942 STAR Protoc, 2025, 6(2):103777 Cancers (Basel), 2023, 15(15)3774
S1217	Cyclophosphamide	Cyclophosphamide(NSC 26271,Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cytophosphane) is a nitrogen mustard alkylating agent from the oxazophorines group.	Neurotherapeutics, 2025, 22(1):e00480 Sci Rep, 2025, 15(1):2893 Front Biosci (Landmark Ed), 2025, 30(11):45744
S1601	Reserpine	Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug. This compound is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).It can be used to induce animal models of Gastric and Intestinal Ulcers.	Mol Psychiatry, 2025, 10.1038/s41380-025-03374-6 J Immunother Cancer, 2024, 12(11)e009805 Int J Mol Sci, 2022, 23(9)4597
S2555	Clarithromycin	Clarithromycin (A-56268) is a macrolide antibiotic and a CYP3A4 inhibitor, used to treat a number of bacterial infections.	Circulation, 2024, 150(7):563-576 Microorganisms, 2022, 10(7)1421 Cell Biol Toxicol, 2021, 10.1007/s10565-021-09646-5
S1645	Ketoprofen	Ketoprofen (RP-19583) is a dual COX1/2 inhibitor, used as a nonsteroidal anti-inflammatory drug to treat arthritis-related inflammatory pains.	Signal Transduct Target Ther, 2022, 7(1):46 J Nucl Med, 2020, jnumed.120.249367
S2076	Lisinopril dihydrate	Lisinopril dihydrate(MK-521 dihydrate) is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.	J Immunother Cancer, 2024, 12(11)e009805
E4900	Enalapril	Enalapril(Eletriptan, Amprace, Vaseretic) is an inhibitor of angiotensin-converting enzyme (ACE), primarily used to treat hypertension, heart failure, and asymptomatic left ventricular dysfunction. It also attenuates frailty in aging mice.	Biochem Pharmacol, 2025, 240:117098
E2970	Gramicidin	Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is an antimicrobial peptide that destroys gram-positive bacteria. It inhibits the growth of bacteria by forming pores and channels in the cell wall, which increase its permeability to monovalent cations.
S5789	Propafenone	Propafenone (SA-79) is an orally active sodium channel blocking agent and a beta-adrenoceptor (β-adrenergic receptor) antagonist. This compound offers a broad spectrum of activity in the treatment of cardiac arrhythmias.It can be used to induce animal models of Heart Failure.
E4812	Fluoxetine	Fluoxetine (LY-110140 free base) is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. This compound is used widely in the treatment of depression, anxiety-related symptoms and also displays anticonvulsant activity.
S4210	Benzocaine	Benzocaine(ethyl 4-aminobenzoate) is the ethyl ester of p-aminobenzoic acid (PABA), it is a local anesthetic commonly used as a topical pain reliever or in cough drops.
E6074^New	Reserpine hydrochloride	Reserpine hydrochloride (Serpivite hydrochloride) is a potent inhibitor of the vesicular monoamine transporter 2 (VMAT2) and depletes monoamines from nerve terminals. It exhibits the potential to produce a pharmacological model of depression in animals.
E0209	Cinobufotalin	Cinobufotalin, extracted from the skin secretion of the giant toad, is a novel SREBP1 inhibitor that suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.