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Insulin Receptor

Other Protein Tyrosine Kinase Related Inhibitors

VEGFR EGFR c-Met PDGFR CSF-1R IGF-1R c-Kit ALK Tie-2 HER2
Cat.No. Product Name Information Product Use Citations Product Validations
S6922 S961 S961 is a biosynthetic insulin receptor antagonist that inhibits cellular proliferation and colony formation in breast tumour cells.
Front Immunol, 2025, 16:1620571
Hepatol Commun, 2025, 9(9)e0793
J Neuroendocrinol, 2024, e13446.
S1091 Linsitinib (OSI-906) Linsitinib (OSI-906) is a selective inhibitor of IGF-1R with IC50 of 35 nM in cell-free assays. It is modestly potent to InsR with IC50 of 75 nM, and shows no activity towards Abl, ALK, BTK, EGFR, FGFR1/2, PKA etc. Phase 3.
Nat Commun, 2025, 16(1):2493
Cell Rep Med, 2025, 6(8):102297
Cell Rep Med, 2025, 6(8):102254
Verified customer review of Linsitinib (OSI-906)
S1124 BMS-754807 BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met (c-Met), Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.
Cell Rep, 2025, 44(8):116149
Commun Med (Lond), 2025, 5(1):206
Front Cell Neurosci, 2024, 18:1441827
Verified customer review of BMS-754807