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Amyloid-β

Neuronal Signaling

GluR GABA Receptor AMPA Receptor-kainate Receptor-NMDA Receptor Gamma-secretase Dopamine Receptor 5-HT Receptor P2 Receptor AChR MAO Beta Amyloid Substance P BACE CaMK NMDAR GlyT Neurotrophin Notch BChE Adenosine Kinase Adenosine Deaminase Neurotensin Receptor Serotonin Transporter Secretase Calcineurin Ion Channel AAK1 Anion Exchanger Cholinesterase (ChE) Glutaminyl Cyclase HCN Channel iGluR Norepinephrine Amyloid-β
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Cat.No. Product Name Information Product Use Citations Product Validations
S6415 Azeliragon (TTP488) Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule that inhibits the receptor for advanced glycation endproducts (RAGE), which is an immunoglobulin-like cell surface receptor overexpressed in brain tissues of patients with AD.
Oncogene, 2025, 44(15):1051-1062
Circ J, 2025, 10.1253/circj.CJ-24-0878
JCI Insight, 2024, e169138
S6415 Azeliragon (TTP488) Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule that inhibits the receptor for advanced glycation endproducts (RAGE), which is an immunoglobulin-like cell surface receptor overexpressed in brain tissues of patients with AD.
Oncogene, 2025, 44(15):1051-1062
Circ J, 2025, 10.1253/circj.CJ-24-0878
JCI Insight, 2024, e169138