AAK1

Other Neuronal Signaling Related Inhibitors

Secretase GluR GABA Receptor Dopamine Receptor 5-HT Receptor P2 Receptor AChR Histamine Receptor MAO Beta Amyloid

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
E0498	BMS-986176	BMS-986176 (LX-9211,AAK1-IN-1) is a highly selective, brain-penetrant, potent AAK1 (adaptor associated kinase 1) inhibitor with an IC50 of 2 nM.	Cell Death Dis, 2022, 13(8):722
E0371^New	SGC-AAK1-1	SGC-AAK1-1 is a chemical probe that functions as a potent and selective inhibitor of AAK1 (AP2-associated kinase 1), exhibiting an IC50 of 270 nM and a Ki of 9 nM. It also demonstrates strong inhibitory activity against BMP2K. This compound serves as a research tool for investigating the Wnt pathway associated with AAK1.