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AAK1

Neuronal Signaling

GluR GABA Receptor AMPA Receptor-kainate Receptor-NMDA Receptor Gamma-secretase Dopamine Receptor 5-HT Receptor P2 Receptor AChR MAO Beta Amyloid Substance P BACE CaMK NMDAR GlyT Neurotrophin Notch BChE Adenosine Kinase Adenosine Deaminase Neurotensin Receptor Serotonin Transporter Secretase Calcineurin Ion Channel AAK1 Anion Exchanger Cholinesterase (ChE) Glutaminyl Cyclase HCN Channel iGluR Norepinephrine Amyloid-β
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  • AAK1 Inhibitors (2)
  • New AAK1 Products
Cat.No. Product Name Information Product Use Citations Product Validations
E0498 BMS-986176 BMS-986176 (LX-9211,AAK1-IN-1) is a highly selective, brain-penetrant, potent AAK1 (adaptor associated kinase 1) inhibitor with an IC50 of 2 nM.
Cell Death Dis, 2022, 13(8):722
E0371New SGC-AAK1-1 SGC-AAK1-1 is a chemical probe that functions as a potent and selective inhibitor of AAK1 (AP2-associated kinase 1), exhibiting an IC50 of 270 nM and a Ki of 9 nM. It also demonstrates strong inhibitory activity against BMP2K. This compound serves as a research tool for investigating the Wnt pathway associated with AAK1.
E0498 BMS-986176 BMS-986176 (LX-9211,AAK1-IN-1) is a highly selective, brain-penetrant, potent AAK1 (adaptor associated kinase 1) inhibitor with an IC50 of 2 nM.
Cell Death Dis, 2022, 13(8):722
E0371New SGC-AAK1-1 SGC-AAK1-1 is a chemical probe that functions as a potent and selective inhibitor of AAK1 (AP2-associated kinase 1), exhibiting an IC50 of 270 nM and a Ki of 9 nM. It also demonstrates strong inhibitory activity against BMP2K. This compound serves as a research tool for investigating the Wnt pathway associated with AAK1.
E0371New SGC-AAK1-1 SGC-AAK1-1 is a chemical probe that functions as a potent and selective inhibitor of AAK1 (AP2-associated kinase 1), exhibiting an IC50 of 270 nM and a Ki of 9 nM. It also demonstrates strong inhibitory activity against BMP2K. This compound serves as a research tool for investigating the Wnt pathway associated with AAK1.