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PPAR Inhibitors

Cat.No. Product Name Information Product Use Citations Product Validations
S7767 AZ6102 AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5 nM for Wnt pathway inhibition in DLD-1 cells.
NPJ Precis Oncol, 2024, 8(1):264
Nat Commun, 2022, 13(1):2070
Sci Adv, 2022, 8(19):eabh2332
S4527 Fenofibric acid Fenofibric acid (NSC 281318, Trilipix, FNF acid) is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides.
BMC Cancer, 2025, 25(1):1404
J Immunother Cancer, 2024, 12(11)e009805
Front Med (Lausanne), 2021, 8:788663
S5824 Cinnamyl alcohol Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. This compound can be significantly attenuated the enhanced expression of obesity-related proteins PPARγ in MDI medium-cultivated 3T3-L1 cells.
S5113 Propyl gallate Propyl gallate (Gallic acid propyl esterZ, n-Propyl gallate) is an antioxidant used in foods especially animal fats and vegetable oils, also in a wide variety of cosmetics and beauty care products.
S7484 FH535 FH535 is a Wnt/β-catenin signaling inhibitor and also a dual PPARγ and PPARδ antagonist.
Int J Biol Sci, 2024, 20(6):2323-2338
Gastroenterology, 2023, S0016-5085(23)00114-2
Gastroenterology, 2023, 164(6):990-1005
Verified customer review of FH535
S7867 Oleuropein Oleuropein is an antioxidant polyphenol isolated from olive leaf. It exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. This compound inhibits PPARγ activity. It exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. This chemical also inhibits aromatase. It induces apoptosis. Phase 2.
Front Endocrinol (Lausanne), 2024, 15:1354435
J Med Virol, 2019, 91(8):1440-1447
S9129 20(S)-Ginsenoside Rh1 20(S)-Ginsenoside Rh1 (Prosapogenin A2, Sanchinoside B2, Sanchinoside Rh1) is one of major bioactive compounds extracted from red ginseng, which has been increasingly used for enhancing cognition and physical health worldwide. It exhibits potent characteristics of anti-inflammatory, antioxidant, immunomodulatory effects, and positive effects on the nervous system. Ginsenoside Rh1 inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β.