Glucagon Receptor

Inhibitory Selectivity

Isoform-specific Inhibitors

Glucagon Receptor Products

Catalog No. Information Product Use Citations Product Validations
P1206New

Tirzepatide (LY3298176)

Tirzepatide (LY3298176, GIP/GLP-1 RA, TZP) is a dual GIP/GLP-1 receptor agonist. Tirzepatide differentially induces internalization of the GIP and GLP-1 receptors with EC50 values of 18.2 nM and 18.1 nM, respectively.

P1203New

Avexitide

Avexitide (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor.

S0555

Adomeglivant

Adomeglivant (LY2409021) is a potent and selective antagonist of glucagon receptor that is used as a chronic treatment for type 2 diabetes.

S9697New

Semaglutide

Semaglutide (Rybelsus, Ozempic, NN9535, OG217SC, NNC 0113-0217), a long-acting glucagon-like peptide 1 (GLP-1) analogue, is a GLP-1 receptor agonist with the potential for the treatment of type 2 diabetes mellitus (T2DM).

S9851New

PF-06882961

PF-06882961, a non-peptide agonist, activates the canonical G protein signaling activity only in the Glucagon-like peptide-1 (GLP-1) receptor with Trp33ECD.

S8517

Lixisenatide

Lixisenatide (Lyxumia, Adlyxin, ZP10A peptide, AVE0010) is a once-daily short-acting glucagon-like peptide-1 (GLP-1) receptor agonist (GLP-1RA) with an IC50 of 1.4 nM for the human GLP-1 receptor in receptor binding studies.

S9307

Shanzhiside methyl ester

Shanzhiside methylester is a principle effective iridoid glycoside of L. rotata and serves as a small molecule glucagon-like peptide-1 (GLP-1) receptor agonist.

S8256

Liraglutide (NN2211)

Liraglutide (Victoza, Liraglutida, Liraglutidum, NN2211) is a long-acting glucagon-like peptide-1(GLP-1) receptor agonist.

S3734

Albiglutide Fragment

Albiglutide fragment is one copy of a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).

Catalog No. Information Product Use Citations Product Validations
P1206New

Tirzepatide (LY3298176)

Tirzepatide (LY3298176, GIP/GLP-1 RA, TZP) is a dual GIP/GLP-1 receptor agonist. Tirzepatide differentially induces internalization of the GIP and GLP-1 receptors with EC50 values of 18.2 nM and 18.1 nM, respectively.

Catalog No. Information Product Use Citations Product Validations
P1203New

Avexitide

Avexitide (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor.

S0555

Adomeglivant

Adomeglivant (LY2409021) is a potent and selective antagonist of glucagon receptor that is used as a chronic treatment for type 2 diabetes.

Catalog No. Information Product Use Citations Product Validations
S9697New

Semaglutide

Semaglutide (Rybelsus, Ozempic, NN9535, OG217SC, NNC 0113-0217), a long-acting glucagon-like peptide 1 (GLP-1) analogue, is a GLP-1 receptor agonist with the potential for the treatment of type 2 diabetes mellitus (T2DM).

S9851New

PF-06882961

PF-06882961, a non-peptide agonist, activates the canonical G protein signaling activity only in the Glucagon-like peptide-1 (GLP-1) receptor with Trp33ECD.

S8517

Lixisenatide

Lixisenatide (Lyxumia, Adlyxin, ZP10A peptide, AVE0010) is a once-daily short-acting glucagon-like peptide-1 (GLP-1) receptor agonist (GLP-1RA) with an IC50 of 1.4 nM for the human GLP-1 receptor in receptor binding studies.

S9307

Shanzhiside methyl ester

Shanzhiside methylester is a principle effective iridoid glycoside of L. rotata and serves as a small molecule glucagon-like peptide-1 (GLP-1) receptor agonist.

S8256

Liraglutide (NN2211)

Liraglutide (Victoza, Liraglutida, Liraglutidum, NN2211) is a long-acting glucagon-like peptide-1(GLP-1) receptor agonist.

Catalog No. Information Product Use Citations Product Validations
S3734

Albiglutide Fragment

Albiglutide fragment is one copy of a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).

Tags: Glucagon Receptor antagonist | Glucagon Receptor agonist | Glucagon Receptor Inhibition| Glucagon Receptor Activation| Glucagon Receptor antagonist | Glucagon Receptor agonist | Glucagon Receptor Activity