Home Protein Tyrosine Kinase ACK

ACK

Other Protein Tyrosine Kinase Related Inhibitors

VEGFR EGFR c-Met PDGFR CSF-1R IGF-1R c-Kit ALK Tie-2 HER2

Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S8272 XMD8-87 XMD8-87 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 38 nmol/L and 113 nmol/L for the D163E and R806Q mutations.
Cancer Cell, 2022, S1535-6108(22)00312-9
S8273 XMD16-5 XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations.
Cell Rep, 2022, 41(11):111827
S2212 AIM-100 AIM-100 is a potent small molecule inhibitor of Ack1 with IC50 of 24nM.
Front Immunol, 2022, 13:864995