GC376

For research use only.

Catalog No.S0475

1 publication

GC376 Chemical Structure

CAS No. 1416992-39-6

GC376 is a 3CLpro (3C-like protease) inhibitor with IC50 of ~ 1.11 μM for the PEDV 3CLpro. GC376 is active against the 3CLpro of multiple coronaviruses, including SARS-CoV.

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Selleck's GC376 has been cited by 1 publication

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Biological Activity

Description GC376 is a 3CLpro (3C-like protease) inhibitor with IC50 of ~ 1.11 μM for the PEDV 3CLpro. GC376 is active against the 3CLpro of multiple coronaviruses, including SARS-CoV.
Targets
PEDV 3CLpro [1]
(Cell-free assay)
1.11 μM
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HG23 NUPEbGZ4SW62aY\pdoFtKGG|c3H5 M4G5O2FvfGm4aYLhcEBi[3Srdnn0fUBi\2GrboP0JG5wem:4aYL1d{Bqdm[nY4Tl[EBqdiCqdX3hckBJTzJ|IHPlcIx{NCCHREWwJF0hOC5|IN88UU4> M1f2UlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkG4O|E{Lz5{M{KxPFcyOzxxYU6=

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Protocol

Solubility (25°C)

Chemical Information

Molecular Weight 507.53
Formula

C21H30N3NaO8S

CAS No. 1416992-39-6
Storage powder
in solvent
Synonyms N/A
Smiles CC(C)CC(C(=O)NC(CC1CCNC1=O)C(O)S(=O)(=O)[O-])NC(=O)OCC2=CC=CC=C2.[Na+]

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Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID