Catalog No.S3081 Synonyms: CDB-2914
Molecular Weight(MW): 433.58
Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.
Purity & Quality Control
Choose Selective Estrogen/progestogen Receptor Inhibitors
|Description||Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.|
Ulipristal acetate has partial agonistic as well as antagonistic effects on the progesterone receptor. It also binds to theglucocorticoid receptor, but has no relevant affinity to the estrogen, androgen and mineralocorticoid receptors.
|In vivo||Based on clinical trials, ulipristal acetate seems to be a reasonably tolerable and effective method of emergency contraception when used within 120 hours of intercourse. Ulipristal acetate is at least as effective as LNG when used within the first 72 hours after unprotected intercourse. However, ulipristal acetate may be more effective than LNG when used between 72 to 120 hours after unprotected intercourse, extending the window of opportunity for emergency contraception. |
|In vitro||DMSO||83 mg/mL (191.42 mM)|
|Ethanol||14 mg/mL (32.28 mM)|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
Enter the chemical formula of a compound to calculate its molar mass and elemental composition:
Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2
Instructions to calculate molar mass (molecular weight) of a chemical compound:
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Clinical Trial Information
|NCT Number||Recruitment||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT01493791||Withdrawn||Urogenital Abnormalities||Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)|National Institutes of Health Clinical Center (CC)||November 8, 2011||Early Phase 1|
|NCT02601196||Not yet recruiting||Women With Leiomyoma After at Least One Unsuccessful IVF Treatment||Sheba Medical Center||September 2016||Phase 4|
|NCT02440750||Not yet recruiting||Uterine Fibroids||University of Cagliari||June 2016||Phase 4|
|NCT02634437||Recruiting||Renal Function||Forest Laboratories||December 2015||Phase 1|
|NCT02825719||Recruiting||Fibroid||Queen Mary Hospital, Hong Kong||November 2015||Phase 4|
|NCT02408770||Not yet recruiting||Breast Cancer||University Hospital of South Manchester NHS Foundation Trust|University of Manchester||September 2015||Phase 2|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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