Beclomethasone dipropionate

Catalog No.S3078 Synonyms: Beclometasone dipropionate

Beclomethasone dipropionate Chemical Structure

Molecular Weight(MW): 521.04

Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.

Size Price Stock Quantity  
In DMSO USD 130 In stock
USD 97 In stock
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Purity & Quality Control

Choose Selective Glucocorticoid Receptor Inhibitors

Biological Activity

Description Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.
Targets
Glucocorticoid receptor [1]
()
In vitro

Beclomethasone dipropionate (BDP) is an anti-inflammatory corticosteroid available for the treatment of asthma and allergic rhinitis (AR). BDP is previously developed as aqueous nasal formulations for the treatment of AR. BDP is also available in dry nasal aerosol formulations as chlorofluoro carbon (CFC) metered-dose inhaler nasal sprays, but CFC-containing formulations have been withdrawn from the market and currently are not available.BDP hydrofluoroalkane (HFA) inhalation aerosol currently is available for patient use and indicated for the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older.BDP HFA nasal aerosol, an intranasal aerosol formulation, has been developed recently for the treatment of AR.

Protocol

Solubility (25°C)

In vitro DMSO 104 mg/mL (199.6 mM)
Ethanol 18 mg/mL (34.54 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 521.04
Formula

C28H37ClO7

CAS No. 5534-09-8
Storage powder
Synonyms Beclometasone dipropionate

Bio Calculators

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT00936793 Completed HIV|Asthma National Institutes of Health Clinical Center (CC) July 6, 2009 Phase 1
NCT02975843 Not yet recruiting Chronic Obstructive Pulmonary Disease|Asthma Chiesi Farmaceutici S.p.A. November 2016 Phase 1
NCT02646904 Recruiting Allergic Rhinitis Stefania La Grutta, MD|Istituto di Biomedicina e Immunologia Molecolare Alberto Monroy February 2016 Phase 4
NCT02513160 Completed Persistent Asthma Teva Branded Pharmaceutical Products, R&D Inc.|Teva Pharmaceutical Industries September 2015 Phase 3
NCT02517099 Recruiting Asthma Imperial College London|National Institute for Health Research, United Kingdom June 2015 Phase 2
NCT02381158 Completed Wheezing Istituto di Biomedicina e Immunologia Molecolare Alberto Monroy February 2015 Phase 4

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