Beclomethasone dipropionate
Catalog No.S3078 Synonyms: Beclometasone dipropionate
Molecular Weight(MW): 521.04
Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.
Purity & Quality Control
Choose Selective Glucocorticoid Receptor Inhibitors
Biological Activity
| Description | Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis. | |
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| In vitro |
Beclomethasone dipropionate (BDP) is an anti-inflammatory corticosteroid available for the treatment of asthma and allergic rhinitis (AR). BDP is previously developed as aqueous nasal formulations for the treatment of AR. BDP is also available in dry nasal aerosol formulations as chlorofluoro carbon (CFC) metered-dose inhaler nasal sprays, but CFC-containing formulations have been withdrawn from the market and currently are not available.BDP hydrofluoroalkane (HFA) inhalation aerosol currently is available for patient use and indicated for the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older.BDP HFA nasal aerosol, an intranasal aerosol formulation, has been developed recently for the treatment of AR. |
Protocol
Solubility (25°C)
| In vitro | DMSO | 104 mg/mL (199.6 mM) |
|---|---|---|
| Ethanol | 18 mg/mL (34.54 mM) | |
| Water | Insoluble |
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Information
| Molecular Weight | 521.04 |
|---|---|
| Formula | C28H37ClO7 |
| CAS No. | 5534-09-8 |
| Storage | powder |
| Synonyms | Beclometasone dipropionate |
Bio Calculators
Molarity Calculator
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Dilution Calculator
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Molarity Calculator
Clinical Trial Information
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT00936793 | Completed | HIV|Asthma | National Institutes of Health Clinical Center (CC) | July 6, 2009 | Phase 1 |
| NCT02975843 | Not yet recruiting | Chronic Obstructive Pulmonary Disease|Asthma | Chiesi Farmaceutici S.p.A. | November 2016 | Phase 1 |
| NCT02646904 | Recruiting | Allergic Rhinitis | Stefania La Grutta, MD|Istituto di Biomedicina e Immunologia Molecolare Alberto Monroy | February 2016 | Phase 4 |
| NCT02513160 | Completed | Persistent Asthma | Teva Branded Pharmaceutical Products, R&D Inc.|Teva Pharmaceutical Industries | September 2015 | Phase 3 |
| NCT02517099 | Recruiting | Asthma | Imperial College London|National Institute for Health Research, United Kingdom | June 2015 | Phase 2 |
| NCT02381158 | Completed | Wheezing | Istituto di Biomedicina e Immunologia Molecolare Alberto Monroy | February 2015 | Phase 4 |
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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