Cortodoxone

Synonyms: 11-Deoxycortisol, cortexolone, 11-Desoxycortisol, 17α,21-dihydroxyprogesterone

Cortodoxone (11-Deoxycortisol, cortexolone, 11-Desoxycortisol, 17α,21-dihydroxyprogesterone), also known as 11-Deoxycortisol, is a glucocorticoid steroid hormone.

Cortodoxone Chemical Structure

Cortodoxone Chemical Structure

CAS: 152-58-9

Purity & Quality Control

Batch: S477501 DMSO] 69 mg/mL] false] ] ] false] ] ] false Purity: 99.91%
99.91

Cortodoxone Related Products

Choose Selective Glucocorticoid Receptor Inhibitors

Biological Activity

Description Cortodoxone (11-Deoxycortisol, cortexolone, 11-Desoxycortisol, 17α,21-dihydroxyprogesterone), also known as 11-Deoxycortisol, is a glucocorticoid steroid hormone.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05633953 Active not recruiting
Cushing''s Syndrome
RECORDATI GROUP
January 16 2023 --
NCT05903716 Recruiting
Acne Vulgaris
Marmara University
September 15 2022 --
NCT04642391 Active not recruiting
Cirrhosis|Adrenal Insufficiency
University of Virginia|American Association for the Study of Liver Diseases
August 2 2021 --
NCT03665194 Completed
Healthy Volunteers
Cassiopea SpA
June 6 2018 Phase 1
NCT01831960 Completed
Acne Vulgaris
Intrepid Therapeutics Inc.
April 2013 Phase 2

Chemical Information & Solubility

Molecular Weight 346.46 Formula

C21H30O4

CAS No. 152-58-9 SDF Download Cortodoxone SDF
Smiles CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C(=O)CO)O)C
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 69 mg/mL ( (199.15 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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