Kaempferol

Catalog No.S2314 Synonyms: Robigenin

Kaempferol Chemical Structure

Molecular Weight(MW): 286.23

Kaempferol, a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.

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1 Customer Review

  • Total cellular protein was harvested after 8 days and the protein levels of adipogenic factors were measured using western blot analysis with specific antibodies (B).

    Food Funct, 2015, 6(8):2824-33. Kaempferol purchased from Selleck.

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Biological Activity

Description Kaempferol, a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.
Targets
ERRα [1] ERRγ [1] Topo I [2] fatty acid synthase [3]
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 FS cells NEnXeohHfW6ldHnvckBie3OjeR?= M{nSOGlvcGmkaYTpc44hd2ZiTl;YOEBmgHC{ZYPz[YQhcW5iSFXLNlk{KE[VIHPlcIx{KGG|c3Xzd4VlKGG|IFiyU|IheHKxZIXjeIlwdiCkeTDINm8zN1S7cj;MVG8h[XO|YYmsJGlEPTB;MT6yJO69VQ>? M3G3elIxPzNzM{W3
human HeLa cells M37XU2Z2dmO2aX;uJIF{e2G7 M1PCVGlvcGmkaYTpc44hd2ZiTWLQNUB1emGwc3\lZ5Rm\CCrbjDoeY1idiCKZVzhJINmdGy|IHHzd4V{e2WmIHHzJIlvcGmkaYTpc44hd2ZiW{PIYWxVSzRidILhcpNxd3K2IHL5JJJieGmmIH\pcJRz[XSrb36gZZN{[XluIFvpQVIvPCEQvF2= MmXPNVk4OjV3N{i=
human MV4-11 cells M3\JTmN6fG:2b4jpZ4l1gSCjc4PhfS=> NF3jc204OiCq NUfJOm5NS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVVZ2LUGxJINmdGy|IHjhdoJwemmwZzDGUHQ{KG23dHH0bY9vKGGodHXyJFczKGi{czDifUB1\XS{YYrvcIl2dSCkYYPl[EBGgiCFeWTvfEBk\WyuII\pZYJqdGm2eTDhd5NigSxiR1m1NF0{NjN2IN88US=> MkTKNlM1OTFyN{O=
MDCK cells NXr3V5BUTnWwY4Tpc44h[XO|YYm= MoWzTY5pcWKrdHnvckBw\iCEQ2LQJIV5eHKnc4Pl[EBqdiCPRFPLJINmdGy|IIXzbY5oKEixZXPod5QhOzN|NEKgd5RicW6rbnesJGlEPTB;ND63JO69VQ>? M4HRXFIyOzV2OECw
human MDA-kb2 cells NF\S[|FHfW6ldHnvckBie3OjeR?= NET3W3lCdnSjZ3;ubZN1KGGldHn2bZR6KGG2IHHu[JJw\2WwIILlZ4VxfG:{IHnuJIh2dWGwIF3ERU1s[jJiY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBFUFRvaX7keYNm\CCudXPp[oVz[XOnIHHjeIl3cXS7IHL5JIx2[2moZYLhd4UhemWyb4L0[ZIh\2WwZTDhd5NigSxiSVO1NF06NjdizszN MV[xPVU6OjJ2NR?=
B16-4A5 cells M{TGNGZ2dmO2aX;uJIF{e2G7 M1GzfmlvcGmkaYTpc44hd2ZibXXsZY5w\2WwZYPpd{BqdiC2aHXvdIh6dGyrbnWtd5RqdXWuYYTl[EBud3W|ZTDCNVYuPEF3IHPlcIx{KGGodHXyJFczKGi{czygTWM2OD1{MDFOwG0> MUKxPVYyPTlzMB?=
human HL60 cells Mme0R5l1d3SxeHnjbZR6KGG|c3H5 M3XmeGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhNPjBiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB{fXK4aY\hcEBifCB3MDD1UUBi\nSncjC3NkBpenNiYomgR2NMQCCjc4PhfS=> NGrPPFUzPTB5NEixOS=>
mouse 3T3L1 cells MV3GeY5kfGmxbjDhd5NigQ>? MV3Jcohq[mm2aX;uJI9nKEGPUFutcYVlcWG2ZXSgZYRqeG:leYTlJIRq\m[ncnXueIlifGmxbjDpckBud3W|ZTCzWFNNOSClZXzsdy=> NVLBW2xJOjB6MkK5NFI>
mouse RAW264.7 cells NXnaT2t2TnWwY4Tpc44h[XO|YYm= NFvUOWlCdnSraX7mcIFudWG2b4L5JIFkfGm4aYT5JIlvKEySUz3zeIlufWyjdHXkJI1wfXOnIGLBW|I3PC55IHPlcIx{KGG|c3Xzd4VlKGG|IH7peJJqfGVibHX2[Ywh[XRiMTD0c{AyODBidV2gZYZ1\XJiMkSgbJJ{KGK7IFfybYV{eyCvZYToc4Q> NELBemUzOTN3M{W0Ny=>
mouse L929 cells MXfGeY5kfGmxbjDhd5NigQ>? NXPJZ2RyUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDUUmYu[WyyaHGtbY5lfWOnZDDjfZRwfG:6aXPpeJkhd2ZibX;1d4UhVDl{OTDj[YxteyCjc4Pld5Nm\CCjczDzeZJ3cX[jbHn0fUB1emWjdHXkJJdqfGhiZIL1[{Bi\nSncjCyJIhzeyCxZjDUUmZidHCqYTD0doVifG2nboS= NUjUUmxyQTJ6N{SxOS=>
human U87 cells MVvDfZRwfG:6aXPpeJkh[XO|YYm= Mk\DOU01OCEQvF2= NFrpUZY4OiCq NH25bmZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBWQDdiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxidnnhZoltcXS7IHH0JFUhfG9iNECgeW0h[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfS=> MmLnNlI5PzF{MUe=
human A549 cells MkfkR5l1d3SxeHnjbZR6KGG|c3H5 NHXiRo82NTRyIN88US=> NHLkd|c4OiCq MlLSR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYYSgOUB1dyB2MDD1UUBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5 MlO0NlI5PzF{MUe=
human MCF7 cells MUfDfZRwfG:6aXPpeJkh[XO|YYm= NELrfIQ2NTRyIN88US=> NFO1[YY4OiCq Mmn1R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYYSgOUB1dyB2MDD1UUBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5 NYHMWYVROjJ6N{GyNVc>
MDA-MB-231 cells NH\T[ZhEgXSxdH;4bYNqfHliYYPzZZk> NFH3b|I2NTRyIN88US=> MV23NkBp M{frdWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj2yN|Eh[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwIHPlcIwhfmmjYnnsbZR6KGG2IEWgeI8hPDBidV2gZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeR?= NHTxWWgzOjh5MUKxOy=>
MDCK cells NWfkW4xoTnWwY4Tpc44h[XO|YYm= M3qxflUxKM7:TR?= NXX3OFJFSW62aY\pdoFtKGGldHn2bZR6KGGpYXnud5QhcW6obIXlcppiKEFidnnyeZMhUDGQMTDBM3BTNzhxM{SgbY5n\WO2ZXSgbY4hVUSFSzDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h\my3b4Lld4NmdmOnIIDvd4l1cX[nIHPlcIx{KGG2IEWwJJVOKGmvbYXuc4ZtfW:{ZYPj[Y5k\SCjc4PhfS=> MWKxPVczQTNzNh?=
human NCI-H2126 cells MVPDfZRwfG:6aXPpeJkh[XO|YYm= M{PnclUuPDBizszN NGLzTJU4OiCq MmDZR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUmNKNUh{MUK2JINmdGy|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBifCB3IITvJFQxKHWPIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[Xl? M{DMNlIzQDdzMkG3
human SMMC7721 cells NXrwNJBwS3m2b4TvfIlkcXS7IHHzd4F6 MV21MVQxKM7:TR?= M1r2dFczKGh? MUnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTUW1EPzd{MTDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZZQhPSC2bzC0NEB2VSCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6 NXTp[XVuOjJ6N{GyNVc>
human PANC1 cells M3jhe2N6fG:2b4jpZ4l1gSCjc4PhfS=> NVfjN4hbPS12MDFOwG0> NV7lWW16PzJiaB?= NX71elYxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWEGQQ{GgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIF1KDVidH:gOFAhfU1iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigQ>? M4\lOlIzQDdzMkG3
human BxPC3 cells NInIfGNEgXSxdH;4bYNqfHliYYPzZZk> NEDTRow2NTRyIN88US=> NE\z[|c4OiCq M1LVOmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGJ5WEN|IHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDheEA2KHSxIESwJJVOKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZk> NITFbYczOjh5MUKxOy=>

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 57 mg/mL warmed (199.14 mM)
Ethanol 3 mg/mL (10.48 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 286.23
Formula

C15H10O6

CAS No. 520-18-3
Storage powder
Synonyms Robigenin

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

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  • Computed Result

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    C2=C1/X C2: LOG(C2):
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    C4=C3/X C4: LOG(C4):
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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID