Kaempferol

Catalog No.S2314

Kaempferol is a natural flavonol, a type of flavonoid, that has been isolated from plant sources.

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Kaempferol Chemical Structure

Kaempferol Chemical Structure
Molecular Weight: 286.23

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Kaempferol is available in the following compound libraries:

Product Information

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Product Description

Biological Activity

Kaempferol is a natural flavonol, a type of flavonoid, that has been isolated from plant sources. It is what gives the flowers of Acacia decurrens and Acacia longifolia their color. The compound has antidepressant properties. The enzyme kaempferol 4’-O-methyltransferase uses S-adenosyl methionine and kaempferol to produce S-adenosylhomocysteine and kaempferide.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesBaboonDogMonkeyRabbitGuinea pigRatHamsterMouse
Weight (kg)121031.80.40.150.080.02
Body Surface Area (m2)0.60.50.240.150.050.0250.020.007
Km factor202012128653
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)

Chemical Information

Download Kaempferol SDF
Molecular Weight (MW) 286.23
Formula

C15H10O6

CAS No. 520-18-3
Storage 3 years -20℃Powder
6 months-80℃in DMSO
Synonyms
Solubility (25°C) * In vitro DMSO 57 mg/mL (199 mM)
Water <1 mg/mL (<1 mM)
Ethanol 57 mg/mL (199 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Research Area

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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