Dehydrogenase Inhibitors

Cat.No.	Product Name	Information	Product Citations
S1501	Mycophenolate mofetil (CellCept)	Mycophenolate mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively.	Front Immunol, 2013, 4, 46
S2776	CPI-613	CPI-613 inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase.
S1404	Trilostane	Trilostane is an inhibitor of 3 β-hydroxysteroid dehydrogenase used in the treatment of Cushing’s syndrome.	Biol Reprod, 2012, 87(2):35
S2055	Gimeracil	Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, which inhibits the early step in homologous recombination for double strand breaks repair.
S1158	MK-8245	MK-8245 is an inhibitor of stearoyl-CoA desaturase (SCD) which targets the liver with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1.

Cat.No.	Product Name	Solubility (25°C)
Cat.No.	Product Name	Water	DMSO	Ethanol
S1501	Mycophenolate mofetil (CellCept)	<1 mg/mL	87 mg/mL	9 mg/mL
S2776	CPI-613	<1 mg/mL	78 mg/mL	78 mg/mL
S1404	Trilostane	<1 mg/mL	66 mg/mL	<1 mg/mL
S2055	Gimeracil	<1 mg/mL	29 mg/mL	<1 mg/mL
S1158	MK-8245	<1 mg/mL	93 mg/mL	<1 mg/mL

Product Categories