| S0470 |
RSV604
|
RSV604 (A-60444), a novel benzodiazepine, is an inhibitor of respiratory syncytial virus (RSV) with EC50 of 0.86 μM. This compound has significant potential for the effective treatment of RSV disease. Phase 2.
|
-
Biomed Environ Sci, 2023, 36(2):135-145
|
|
| E1398 |
Rilematovir
|
Rilematovir (JNJ-678, JNJ-53718678) is an antiviral agent that inhibits respiratory syncytial virus (RSV) with EC50 of 1.2 nM in HBECs. This compound is also a fusion protein inhibitor.
|
|
|
| E1887New |
Sisunatovir hydrochloride
|
Sisunatovir hydrochloride (RV521 hydrochloride) is an orally available and potent inhibitor of the RSV-Fprotein with IC50 values of 1.4 nM and 1.0 nM for RSV A, RSV B, respectively. It effectively reduces RSV viral load and disease severity in humans and has demonstrated a good safety profile in the treatment of an established RSV infection.
|
|
|
| S8588 |
Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor)
|
ACSS2 inhibitor is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2). ACSS2 inhibitor also inhibits the respiratory syncytial virus (RSV).
|
-
Nat Commun, 2025, 16(1):2071
-
Cell Death Dis, 2025, 16(1):650
-
Cell Rep, 2025, 44(7):115947
|
|