Progesterone Receptor Inhibitors

Cat.No. Product Name Information Product Use Citations Product Validations
E0937 Segesterone acetate Segesterone acetate (Nestoron, ST-1435) is a synthetic progestin that binds to the progesterone receptor with EC50 of 50.3 nM.
S4638 Desogestrel Desogestrel (Cerazette, Desogen, Desogestrelum, Org-2969) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
S4883 Lynestrenol Lynestrenol (Ethinylestrenol) is a synthetic progestational hormone, an agonist of the progesterone receptor and has weak androgenic and estrogenic activity.
S3635 Medroxyprogesterone Medroxyprogesterone (MP) is a synthetic pregnane steroid and a derivative of progesterone. It is a potent progesterone receptor agonist.
S4097 Dydrogesterone Dydrogesterone (NSC 92336) is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.
S4507 17-Hydroxyprogesterone 17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.
E2664 Cridanimod Cridanimod, a low-Mw interferon-inducer (IFN-inducer), recognizes the intracellular signaling protein stimulator of interferon genes (STING), resulting in the STING-TBK1-IRF3 pathway activation and synthesis of type I IFNs (subtypes IFN-α and IFN-β).
E0742 Melengestrol Acetate Melengestrol Acetate, progestational steroid suppress the AT3 tumour.