Progesterone Receptor Antagonist

Featured Inhibitors
Inhibitors (2)
Modulator (1)
Chemicals (5)
Agonists (9)
Antagonist (1)

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S2606	Mifepristone (RU-486)	Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.Mifepristone (RU486) can be used to induce animal models of Spontaneous Abortion.	Alcoholism: Clinical and Experimental Research, May 2020, 1025-1036 Scientific Reports, March 24, 2020, 5363 Frontiers in Immunology, August 12, 2022, 863034

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S2606

Mifepristone (RU-486)

Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.Mifepristone (RU486) can be used to induce animal models of Spontaneous Abortion.

Alcoholism: Clinical and Experimental Research, May 2020, 1025-1036

Scientific Reports, March 24, 2020, 5363

Frontiers in Immunology, August 12, 2022, 863034

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