Teduglutide

For research use only.

Catalog No.S9935 Synonyms: ALX-0600, Gattex, Revestive, TAK 633

Teduglutide Chemical Structure

CAS No. 197922-42-2

Teduglutide (ALX-0600, Gattex, Revestive, TAK 633) is an analogue of human glucagon-like peptide-2 (GLP-2) and binds to the GLP-2 receptors. Teduglutide prolongs the intestinotrophic properties of GLP-2 in animal models.

Purity & Quality Control

Choose Selective Glucagon Receptor Inhibitors

Biological Activity

Description Teduglutide (ALX-0600, Gattex, Revestive, TAK 633) is an analogue of human glucagon-like peptide-2 (GLP-2) and binds to the GLP-2 receptors. Teduglutide prolongs the intestinotrophic properties of GLP-2 in animal models.

Protocol

Solubility (25°C)

Chemical Information

Molecular Weight 3752.08
Formula

C164H252N44O55S

CAS No. 197922-42-2
Storage powder
in solvent
Synonyms ALX-0600, Gattex, Revestive, TAK 633

In vivo Formulation Calculator (Clear solution)

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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04883606 Not yet recruiting -- Short Bowel Syndrome Takeda July 1 2021 --
NCT04465396 Completed Drug: Teduglutide|Device: Syringe|Device: Pen injector Healthy Volunteers Shire|Takeda Development Center Americas Inc.|Takeda May 13 2021 Phase 1
NCT04733066 Recruiting Drug: Teduglutide Short Bowel Syndrome|Intestinal Failure Charite University Berlin Germany|Takeda September 1 2020 --
NCT03860688 Recruiting Drug: TED + glucose Hyperlipidemias University Health Network Toronto May 1 2019 Phase 2|Phase 3
NCT03442972 Active not recruiting Drug: Teduglutide|Drug: Placebo Hyperlipidemias University Health Network Toronto|Kensington Screening Clinic January 17 2019 Phase 2|Phase 3
NCT03422666 Recruiting Drug: Teduglutide|Drug: Placebo Hyperlipidemias University Health Network Toronto September 21 2018 Phase 2|Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID