Myricetin

For research use only.

Catalog No.S2326 Synonyms: Cannabiscetin

2 publications

Myricetin Chemical Structure

Molecular Weight(MW): 318.24

Myricetin, a natural flavonoid with antioxidant and anti tumor properties, is a novel inhibitor of MEK1 activity and transformation of JB6 P+ mouse epidermal cells. It also inhibits PI3Kγ with Kd of 0.17 μM.

Size Price Stock Quantity  
10mM (1mL in DMSO) USD 70 In stock
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Biological Activity

Description Myricetin, a natural flavonoid with antioxidant and anti tumor properties, is a novel inhibitor of MEK1 activity and transformation of JB6 P+ mouse epidermal cells. It also inhibits PI3Kγ with Kd of 0.17 μM.
Targets
MEK1 [4] PI3Kγ [5]
0.17 μM(Kd)
In vitro

Myricetin(Cannabiscetin) is a flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants, which has antioxidant and anti tumor properties. Myricetin has antioxidant properties. In vitro research suggests that myricetin in high concentrations can modify LDL cholesterol such that uptake by white blood cells is increased. [1] Studies shows that high myricetin consumption reduces the risk of prostate cancer and pancreatic cancer. [2] [3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HT-29 cells MUfGeY5kfGmxbjDhd5NigQ>? Mn\ESIV{\W6|aYTpfoF1cW:wIH;mJGdRWjN3IILlZ4VxfG:{IHnuJIh2dWGwIFjUMVI6KGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gfoFxemmwYYP0MYlv\HWlZXSg[Jlv[W2rYzDtZZN{KHKnZHnzeJJq[nW2aX;uJIFnfGW{IEGwJI1qdnNuIFnDOVA:Oi5zMjFOwG0> MXqyOFkxODR2Nx?=
HeLa cells Ml[wSpVv[3Srb36gZZN{[Xl? NFjmVXFKdmirYnn0bY9vKG:oIF3SVFEhfHKjboPm[YN1\WRiaX6gbJVu[W5iSHXMZUBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIGuzTH1NXEN2IITyZY5{eG:{dDDifUBz[XCrZDDmbYx1emG2aX;uJIF{e2G7LDDLbV0zNjRizszN NXPu[VNCOTl5MkW1O|g>
HCT116 cells M1;oTWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWPvZYhXPDhiaB?= NIjSTHJIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBJS1RzMU[gZ4VtdHNib4\ldoV5eHKnc4PpcochWEl|S3HsdIhiKEhzMES3VkBufXSjboSgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OD12LkGg{txO NIrvNGczOjJzMkeyNS=>
human 22Rv1 cells MnPRVJJwdGmoZYLheIlwdiCjc4PhfS=> MmPENVQ1KGh? NVnKe|kzSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjCyNnJ3OSClZXzsd{BqdmO3YnH0[YQhfXBidH:gNVQ1KGi{czDifUBEd3WudHXyJJBienSrY3zlJINwfW62IHHu[EB{cXqnIHHuZYx6gmW{LDDJR|UxRTF|LkGg{txO MWmyNlc5QThzMh?=
human SKBR3 cells M33vT2Z2dmO2aX;uJIF{e2G7 M{PLNlI1KGh? NEHPXlBFcXOybHHj[Y1mdnRib3[gS20u[3l|QjDmdo9uKEi|cEmwJIlvKGi3bXHuJHNMSlJ|IHPlcIx{KGGodHXyJFI1KGi{czDifUBndHWxcnXzZ4Vv[2VicH;sZZJqgmG2aX;uJIF{e2G7LDDJR|UxRTF|LkWg{txO M4mwflI1PTR6MkC3
human U2OS cells NYW3TJFTTnWwY4Tpc44h[XO|YYm= NX7wcnl4PSCq MUfB[49vcXO2IHHjeIl3cXS7IHH0JGdRWjN3IILlZ4VxfG:{IHnuJIh2dWGwIGWyU3Mh[2WubIOgZ49mgHC{ZYPzbY5oKEejbEStWnAyPi2WRW[gZZN{\XO|ZXSgZZMh[mW2YTDhdpJme3SrbjD0doFve2yxY3H0bY9vKGGodHXyJFUhcHK|IHL5JIJmfGFibHHjeIFu[XOnIILldI9zfGW{IHflcoUh[XO|YYmsJGVEPTB;MUSuO{DPxE1? MV:yOFkxODR2Nx?=
human H9 cells MXHGeY5kfGmxbjDhd5NigQ>? NGHkXmI{KGSjeYO= MnHURY51cX[rcnHsJIFkfGm4aYT5JIFo[Wmwc4SgTGlXOSB|QjDpcoZm[3SnZDDpckBpfW2jbjDIPUBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oII\pdoFtKHKncHzpZ4F1cW:wIHHmeIVzKDNiZHH5d{BjgSCyMkSgZY51cWenbjDjZZB1fXKnIHHzd4F6NCCHQ{WwQVM2KM7:TR?= NX74WoJJQDF3OEG2OC=>
NCI-60 human tumor cell line MmK2R5l1d3SxeHnjbZR6KGG|c3H5 MWHJckB3cXS{bzDjfZRwfG:6aXOgdI91\W6leTDh[4FqdnO2IF7DTU03OCCqdX3hckB1fW2xcjDj[YxtKGyrbnWsJGdKPTB;M{[g{txO NGDHcm86PjN{M{[2
human HL60 cells MV;Qdo9tcW[ncnH0bY9vKGG|c3H5 NVK5[oV{OzBizszN MXe0PEBp NIHZUVZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjMOlAh[2WubIOgZZQhOzBidV2gZYZ1\XJiNEigbJJ{KGK7IF3UV{Bie3OjeR?= NYrENG9UOTh{NUi0OFA>
mouse L929 cells NWi2PFh7TnWwY4Tpc44h[XO|YYm= NVy3WodIOiCq Mm\VTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCWTl[tZYxxcGFvaX7keYNm\CCleYTveI95cWOrdImgc4YhdW:3c3WgUFkzQSClZXzsd{Bie3Onc4Pl[EBieyC|dYL2bZZidGm2eTD0doVifGWmIIfpeIgh\HK3ZzDh[pRmeiB{IHjyd{Bw\iCWTl\hcJBp[SC2cnXheI1mdnR? NV\NNnpoQTJ6N{SxOS=>

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 63 mg/mL (197.96 mM)
Ethanol 9 mg/mL warmed (28.28 mM)
Water Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
4% DMSO+30% PEG 300+ddH2O
For best results, use promptly after mixing.
5mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 318.24
Formula

C15H10O8

CAS No. 529-44-2
Storage powder
in solvent
Synonyms Cannabiscetin
Smiles OC1=CC(=C2C(=O)C(=C(OC2=C1)C3=CC(=C(O)C(=C3)O)O)O)O

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID