Myricetin

For research use only. Not for use in humans.

Catalog No.S2326 Synonyms: Cannabiscetin

1 publication

Myricetin Chemical Structure

Molecular Weight(MW): 318.24

Myricetin, a natural flavonoid with antioxidant and anti tumor properties, is a novel inhibitor of MEK1 activity and transformation of JB6 P+ mouse epidermal cells. It also inhibits PI3Kγ with Kd of 0.17 μM.

Size Price Stock Quantity  
10mM (1mL in DMSO) USD 70 In stock
USD 50 In stock
USD 70 In stock
USD 120 In stock
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Selleck's Myricetin has been cited by 1 publication

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Biological Activity

Description Myricetin, a natural flavonoid with antioxidant and anti tumor properties, is a novel inhibitor of MEK1 activity and transformation of JB6 P+ mouse epidermal cells. It also inhibits PI3Kγ with Kd of 0.17 μM.
Targets
MEK1 [4] PI3Kγ [5]
0.17 μM(Kd)
In vitro

Myricetin(Cannabiscetin) is a flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants, which has antioxidant and anti tumor properties. Myricetin has antioxidant properties. In vitro research suggests that myricetin in high concentrations can modify LDL cholesterol such that uptake by white blood cells is increased. [1] Studies shows that high myricetin consumption reduces the risk of prostate cancer and pancreatic cancer. [2] [3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HT-29 cells M2LUe2Z2dmO2aX;uJIF{e2G7 Ml[3SIV{\W6|aYTpfoF1cW:wIH;mJGdRWjN3IILlZ4VxfG:{IHnuJIh2dWGwIFjUMVI6KGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gfoFxemmwYYP0MYlv\HWlZXSg[Jlv[W2rYzDtZZN{KHKnZHnzeJJq[nW2aX;uJIFnfGW{IEGwJI1qdnNuIFnDOVA:Oi5zMjFOwG0> NGjJPIczPDlyMES0Oy=>
HeLa cells MWTGeY5kfGmxbjDhd5NigQ>? NIHKfG5KdmirYnn0bY9vKG:oIF3SVFEhfHKjboPm[YN1\WRiaX6gbJVu[W5iSHXMZUBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIGuzTH1NXEN2IITyZY5{eG:{dDDifUBz[XCrZDDmbYx1emG2aX;uJIF{e2G7LDDLbV0zNjRizszN MWWxPVczPTV5OB?=
HCT116 cells MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{TMOVQ5KGh? MUnHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDIR3QyOTZiY3XscJMhd3[ncnX4dJJme3OrbnegVGk{U2GucHjhJGgyODR5UjDteZRidnRiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NF01NjFizszN NHLkWYMzOjJzMkeyNS=>
human 22Rv1 cells MnLZVJJwdGmoZYLheIlwdiCjc4PhfS=> MUGxOFQhcA>? NELBTXNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIEKyVpYyKGOnbHzzJIlv[3WkYYTl[EB2eCC2bzCxOFQhcHK|IHL5JGNwfWy2ZYKgdIFzfGmlbHWgZ492dnRiYX7kJJNqgmViYX7hcJl7\XJuIFnDOVA:OTNwMTFOwG0> MnzPNlI4QDl6MUK=
human SKBR3 cells MVPGeY5kfGmxbjDhd5NigQ>? MWqyOEBp M4LQdmRqe3CuYXPlcYVvfCCxZjDHUU1kgTOEIH\yc40hUHOyOUCgbY4hcHWvYX6gV2tDWjNiY3XscJMh[W[2ZYKgNlQhcHK|IHL5JIZtfW:{ZYPj[Y5k\SCyb3zhdol7[XSrb36gZZN{[XluIFnDOVA:OTNwNTFOwG0> M{PN[VI1PTR6MkC3
human U2OS cells NIj2S5NHfW6ldHnvckBie3OjeR?= MWO1JIg> M13KZ2Fod26rc4SgZYN1cX[rdImgZZQhT1CUM{WgdoVk\XC2b4KgbY4hcHWvYX6gWVJQWyClZXzsd{Bkd2W6cILld5NqdmdiR3HsOE1XWDF4LWTFWkBie3Onc4Pl[EBieyCkZYThJIFzemW|dHnuJJRz[W6|bH;jZZRqd25iYX\0[ZIhPSCqcoOgZpkh[mW2YTDsZYN1[W2jc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhTUN3ME2xOE44KM7:TR?= NHXyUm8zPDlyMES0Oy=>
human H9 cells M4LMOWZ2dmO2aX;uJIF{e2G7 M2nBeVMh\GG7cx?= NXzIRXpqSW62aY\pdoFtKGGldHn2bZR6KGGpYXnud5QhUEmYMTCzRkBqdm[nY4Tl[EBqdiCqdX3hckBJQSClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJJZqemGuIILldIxq[2G2aX;uJIFnfGW{IEOg[IF6eyCkeTDwNlQh[W62aXflckBk[XC2dYLlJIF{e2G7LDDFR|UxRTN3IN88US=> MUm4NVU5OTZ2
NCI-60 human tumor cell line NIDxeo5EgXSxdH;4bYNqfHliYYPzZZk> MmPFTY4hfmm2cn:gZ5l1d3SxeHnjJJBwfGWwY4mgZYdicW6|dDDOR2kuPjBiaIXtZY4hfHWvb4KgZ4VtdCCuaX7lMEBIUTVyPUO2JO69VQ>? NUnPXHJRQTZ|MkO2Oi=>
human HL60 cells MoC0VJJwdGmoZYLheIlwdiCjc4PhfS=> NXfXXlZvOzBizszN M2D4V|Q5KGh? NX;kcnRpSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIUFYxKGOnbHzzJIF1KDNyIIXNJIFnfGW{IES4JIhzeyCkeTDNWHMh[XO|YYm= MkT1NVgzPTh2NEC=
mouse L929 cells MUPGeY5kfGmxbjDhd5NigQ>? Ml;SNkBp MoXUTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCWTl[tZYxxcGFvaX7keYNm\CCleYTveI95cWOrdImgc4YhdW:3c3WgUFkzQSClZXzsd{Bie3Onc4Pl[EBieyC|dYL2bZZidGm2eTD0doVifGWmIIfpeIgh\HK3ZzDh[pRmeiB{IHjyd{Bw\iCWTl\hcJBp[SC2cnXheI1mdnR? Mly4PVI5PzRzNR?=

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 63 mg/mL (197.96 mM)
Ethanol 9 mg/mL warmed (28.28 mM)
Water Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
4% DMSO+30% PEG 300+ddH2O
For best results, use promptly after mixing.
5mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 318.24
Formula

C15H10O8

CAS No. 529-44-2
Storage powder
in solvent
Synonyms Cannabiscetin
Smiles OC1=CC(=C2C(=O)C(=C(OC2=C1)C3=CC(=C(O)C(=C3)O)O)O)O

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID