Necroptosis

Cat.No. Product Name Information Product Use Citations Product Validations
E5880New Necrocide1 Necrocide1 is a potent inducer of cancer cell necrosis and displays antiproliferative activity with IC50 values of 0.48 nM and 2 nM for MCF-7 and PC3 cells, respectively. This compound also exerts potent antitumor effects in xenograft models.
E7531 Necrostatin 2 Necrostatin-2 is a potent inhibitor of necroptosis with an EC50 of 50 nM in FADD-deficient Jurkat T cells treated with TNF-α.