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S3279
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Polyphyllin B (Formosanin C)
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Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. This compound induces apoptosis.
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S3280
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Linderene
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Linderene (Lindenenol) is a furanosesquiterpenoid isolated from Lindera pulcherrima with antibacterial and antioxidant activities.
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S3281
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Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobioside
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Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobioside (Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobiosiden, Quercetin-3-O-beta-D-glucose-7-O-beta-D-gentiobioside) is an active constituent of Descurainiae Semen.
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S3298
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Caulophylline (N-Methylcytisine)
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Caulophylline (N-Methylcytisine, Caulophyllin, NMC) is a tricyclic quinolizidine alkaloid with anti-inflammatory activities. It binds to nicotinic acetylcholine receptors (nAChR) from squid optical ganglia with Kd of 50 nM. This compound significantly reduces myeloperoxidase (MPO) activity and blocks the activation of NF-κB by inhibiting IκB and IKK phosphorylation.
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S3302
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β,β-dimethyl-acryl-alkannin
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β,β-dimethyl-acryl-alkannin (AN-I, β,β-Dimethylacrylalkannin) is a napthoquinone isolated from roots of Arnebia nobilis Reichb.f. that has the potential to be used as an anti-aging ingredient.
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S3304
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Stylopine
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Stylopine ((R,S)-Stylopine, Tetrahydrocoptisine) reduces nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta), and the IL-6 production and cyclooxygenase-2 (COX-2) activity caused by the LPS stimulation. This compound is a major component of the leaf of Chelidonium majus L.
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S3306
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1,1,1,1-Kestohexaose
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1,1,1,1-Kestohexaose is a major DP 6 fructan in crested wheatgrass leaves.
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S3205
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Perillaldehyde
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Perillaldehyde (Perilladehyde, Perillal, PAE, PA), the main component of Perilla frutescens (a traditional medicinal antioxidant herb), inhibits BaP-induced AHR activation and ROS production, inhibits BaP/AHR-mediated release of the CCL2 chemokine, and activats the NRF2/HO1 antioxidant pathway.
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S3227
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5,7-Dimethoxyflavone
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5,7-Dimethoxyflavone (5,7-DMF) is an inhibitor of cytochrome P450 (CYP) 3As that markedly decreases the expression of CYP3A11 and CYP3A25 in the liver. This compound is also a potent Breast Cancer Resistance Protein (BCRP, ABCG2) inhibitor. It is one of the major components of Kaempferia parviflora with anti-obesity, anti-inflammatory, and antineoplastic effects.
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S3237
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Deoxyaconitine
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3-Deoxyaconitine is a diterpenoid alkaloid isolated from the root of Aconitum Carmichaeli Debx.
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S3241
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Loureirin A
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Loureirin A is a flavonoid extracted from the red resin of the herbs of Dracaena cochinchinensis, which is known as Dragon's Blood. This compound inhibits platelet activation by an impairment of PI3K/Akt signaling. It also inhibits Akt phosphorylation.
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S3247
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Icariside I
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Icariside I (Icarisid I) is one of the main components in Epimedii Folium that significantly stimulates cell proliferation and osteoblasts differentiation.
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S3249
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Corypalmine
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Corypalmine ((R)-(+)-Corypalmine), an alkaloid isolated from Stephania cepharantha, is an inhibitor of prolyl endopeptidase/oligopeptidase (PREP/POP) with IC50 of 128.0 μM.
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S3255
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Pectolinarigenin
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Pectolinarigenin, an active anti-inflammatory ingredient in Cirsium chanroenicum, is a dual inhibitor of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX).
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S3256
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Tectochrysin
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Tectochrysin (Techtochrysin, NSC 80687) is one of the major flavonoids of Alpinia oxyphylla Miquel. This compound significantly increases the expression of DR3, DR4 and Fas and inhibits activity of NF-κB. It induces apoptotic cell death.
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S3257
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Rebaudioside B
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Rebaudioside B (Reb B) is one of the minor steviol glycosides (SGs) isolated from Stevia rebaudiana and has a better taste quality than many of the major SGs.
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S3259
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Rebaudioside D
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Rebaudioside D (Reb D) is one of the several glycosides (SGs) found in the leaves of Stevia rebaudiana (Bertoni) which has been identified as a potential sweetener.
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S3272
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Steviol (Hydroxydehydrostevic acid)
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Steviol (Hydroxydehydrostevic acid, Hydroxy Dehydrostevic Acid, NSC 226902), a major metabolite of the sweetening compound stevioside, inhibits CFTR activity, reduces AQP2 expression and promotes AQP2 degradation.
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S3274
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Glucosyl-vitexin
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Glucosyl-vitexin (Glucosylvitexin), the major C-glycosylflavone present in millet, inhibits thyroid peroxidase (TPO) activity.
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S3282
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Rebaudioside M
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Rebaudioside M, isolated from Stevia rebaudiana Bertoni, is a natural non-caloric potential sweetener in food and beverage products.
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