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HIV Protease Inhibitors

Cat.No. Product Name Information Product Use Citations Product Validations
S2319 Limonin Limonin is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.
Int J Biol Sci, 2019, 15(11):2497-2508
Biomed Pharmacother, 2019, 118:109366
Food Chem Toxicol, 2019, 125:621-628
S1639 Amprenavir (VX-478) Amprenavir (VX-478, 141W94, KVX-478) is a potent PXR-selective agonist and an HIV protease inhibitor, used to treat HIV.
Nat Commun, 2023, 14(1):5034
Sci Rep, 2021, 11(1):19443
Antimicrob Agents Chemother, 2020, AAC.00872-20
S6625 Temsavir (BMS-626529) Temsavir (BMS-626529) is a novel small-molecule HIV-1 attachment inhibitor active against both CCR5- and CXCR4-tropic viruses.
J Virol, 2023, 97(10):e0115423
S6581 Fosamprenavir calcium salt Fosamprenavir(GW433908G) is a pro-drug of the protease inhibitor and antiretroviral drug amprenavir. It is used for the treatment of HIV-1 infections.
Antimicrob Agents Chemother, 2020, AAC.00872-20
S3287 Rosamultin Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina L. that inhibits HIV-1 protease. This compound has protective effects on H2O2-induced oxidative damage and apoptosis.
S9010 Bevirimat Bevirimat (MPC-4326, PA-457, YK-FH312), the prototype Human Immunodeficiency Virus type 1 (HIV-1) maturation inhibitor, is highly potent in cell culture and efficacious in HIV-1 infected patients.
S9625 Saquinavir (Ro 31-8959) Saquinavir (Ro 31-8959,SAQ) is a potent and selective inhibitor of HIV proteinase with a mean IC50 of 2.7 nM in JM cells.
S6929 Dextran sulfate sodium (DSS) Dextran sulfate sodium (DSS) is a potent and selective inhibitor of human immunodeficiency virus type 1 (HIV-1) in vitro that inhibits virus adsorption to the host cells, and this compound can be used to induce animal models of Enteritis, Ulcerative Colitis.
E0943 NBD-556 NBD-556 is a novel human immunodeficiency virus type 1 (HIV-1) entry inhibitor that block the gp120-CD4 interaction.
S9633 GS-6207 (Lenacapavir) GS-6207 (Lenacapavir) is a HIV-1 capsid inhibitor. It shows anti-HIV activity with an EC50 of 0.1 nM in MT-4 cells.
E4466 Saquinavir Mesylate Saquinavir mesylate (Ro 31-8959/003) is a potent inhibitor of HIV Protease used in antiretroviral therapy. It blocks proteolysis of polyproteins containing either wild-type or single-chain dimer retroviral proteinase (PR).
E1243 Azvudine Azvudine (RO-0622) is a novel nucleoside reverse transcriptase inhibitor with antiviral activity against human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV), potently inhibits HIV-1 (EC50 range 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM).
S6999 Chloroquine Chloroquine is an antimalarial drug and autophagy/lysosome inhibitor. Chloroquine also suppresses Toll-like receptor-9 (TLR9) protein expression. Chloroquine is highly effective agianst SARS-CoV-2 (COVID-19) infection with EC50 of 1.13 μM in Vero E6 cells. Chloroquine has anti-HIV-1 activity.
Signal Transduct Target Ther, 2025, 10(1):26
Cell Discov, 2025, 11(1):15
Cell Metab, 2025, S1550-4131(25)00149-4
S3494 Vicriviroc maleate Vicriviroc maleate(SCH-417690 maleate,SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM, and also inhibits HIV-1 in PBMC cells.
Breast Cancer Res, 2021, 23(1):11