GluCls

Other Autophagy Related Inhibitors

Autophagy LRRK2 OGA Mitophagy ULK LC3 Beclin ATTECs Cell wall

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S1351	Ivermectin	Ivermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug. This compound is a specific positive allosteric effector of P2X4 and α7 nicotinic acetylcholine receptors (nAChRs). It is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. This chemical induces autophagy through the AKT/mTOR signaling pathway and mitophagy.	Nat Commun, 2025, 16(1):7156 J Adv Res, 2025, S2090-1232(25)00874-4 Biomed Pharmacother, 2025, 189:118248
S3713	Moxidectin	Moxidectin (Milbemycin B) is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari.	Viruses, 2025, 17(2)220

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S1351

Ivermectin

Ivermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug. This compound is a specific positive allosteric effector of P2X4 and α7 nicotinic acetylcholine receptors (nAChRs). It is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. This chemical induces autophagy through the AKT/mTOR signaling pathway and mitophagy.

Nat Commun, 2025, 16(1):7156

J Adv Res, 2025, S2090-1232(25)00874-4

Biomed Pharmacother, 2025, 189:118248

S3713

Moxidectin

Moxidectin (Milbemycin B) is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari.

Viruses, 2025, 17(2)220