OGA

Other Autophagy Related Inhibitors

Autophagy LRRK2 Mitophagy ULK LC3 Beclin ATTECs Cell wall GluCls

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S7213	Thiamet G	Thiamet G is a potent, selective O-GlcNAcase inhibitor with K_iof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal –hexosaminidase.	Nat Commun, 2025, 16(1):1274 Nat Commun, 2025, 16(1):6807 Proc Natl Acad Sci U S A, 2025, 122(32):e2502687122
S8890	MK-8719	MK-8719 is a selective and potent small molecule inhibitor of the O-GlcNAcase (OGA) enzyme with ki of 7.9nM for hOGA.

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S7213

Thiamet G

Thiamet G is a potent, selective O-GlcNAcase inhibitor with K_iof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal –hexosaminidase.

Nat Commun, 2025, 16(1):1274

Nat Commun, 2025, 16(1):6807

Proc Natl Acad Sci U S A, 2025, 122(32):e2502687122

S8890

MK-8719

MK-8719 is a selective and potent small molecule inhibitor of the O-GlcNAcase (OGA) enzyme with ki of 7.9nM for hOGA.