OGA
Inhibitory Selectivity
OGA Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S8890New |
MK-8719MK-8719 is a selective and potent small molecule inhibitor of the O-GlcNAcase (OGA) enzyme with ki of 7.9nM for hOGA. |
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| S7213 |
Thiamet GThiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal –hexosaminidase. |
Jurkat cells were treated with DMSO, paclitaxel, thiamet-G or paclitaxel plus thiamet-G for 3 h, and then cells were incubated on ice for 20 min, microtubule (green) and DAPI (blue) were immunostained and shown.
|
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S8890New |
MK-8719MK-8719 is a selective and potent small molecule inhibitor of the O-GlcNAcase (OGA) enzyme with ki of 7.9nM for hOGA. |
||
| S7213 |
Thiamet GThiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal –hexosaminidase. |
Jurkat cells were treated with DMSO, paclitaxel, thiamet-G or paclitaxel plus thiamet-G for 3 h, and then cells were incubated on ice for 20 min, microtubule (green) and DAPI (blue) were immunostained and shown.
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