DAPK

Choose Selective DAPK Inhibitors

DAPK Products

  • All (1)
  • DAPK Inhibitor (1)
  • New DAPK Products
Catalog No. Product Name Information Product Use Citations Product Validations
S1113 GSK690693 GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM in cell-free assays, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. GSK690693 also potently inhibits AMPK and DAPK3 from the CAMK family with IC50 of 50 nM and 81 nM, respectively. GSK690693 affects Unc-51-like autophagy activating kinase 1 (ULK1) activity, robustly inhibits STING-dependent IRF3 activation. Phase 1.
Oncogene, 2021, 10.1038/s41388-021-01932-0
Breast Cancer Res, 2021, 23(1):81
Cancer Discov, 2021, candisc.1265.2020
S1113 GSK690693 GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM in cell-free assays, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. GSK690693 also potently inhibits AMPK and DAPK3 from the CAMK family with IC50 of 50 nM and 81 nM, respectively. GSK690693 affects Unc-51-like autophagy activating kinase 1 (ULK1) activity, robustly inhibits STING-dependent IRF3 activation. Phase 1.
Oncogene, 2021, 10.1038/s41388-021-01932-0
Breast Cancer Res, 2021, 23(1):81
Cancer Discov, 2021, candisc.1265.2020