ADAM10

Cat.No. Product Name Information Product Use Citations Product Validations
S8660 GI254023X (GI4023) GI254023X (GI 4023, SRI028594) is a selective inhibitor of ADAM10 with 100-fold selectivity for ADAM10 over ADAM17. The IC50 values for recombinant ADAM10 amd ADAM17 are 5.3 nM and 541 nM, respectively.GI254023X can inhibit MMP9.
J Biol Chem, 2026, S0021-9258(26)01946-0
J Extracell Biol, 2026, 5:e70129
Signal Transduct Target Ther, 2025, 10(1):387