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ADAM10

Apoptosis

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Cat.No. Product Name Information Product Use Citations Product Validations
S8660 GI254023X GI254023X (GI 4023, SRI028594) is a selective inhibitor of ADAM10 with 100-fold selectivity for ADAM10 over ADAM17. The IC50 values for recombinant ADAM10 amd ADAM17 are 5.3 nM and 541 nM, respectively.GI254023X can inhibit MMP9.
Cell Death Dis, 2025, 16(1):34
Alzheimers Res Ther, 2024, 16(1):160
J Biol Chem, 2024, 300(12):107930
S8660 GI254023X GI254023X (GI 4023, SRI028594) is a selective inhibitor of ADAM10 with 100-fold selectivity for ADAM10 over ADAM17. The IC50 values for recombinant ADAM10 amd ADAM17 are 5.3 nM and 541 nM, respectively.GI254023X can inhibit MMP9.
Cell Death Dis, 2025, 16(1):34
Alzheimers Res Ther, 2024, 16(1):160
J Biol Chem, 2024, 300(12):107930