Thioredoxin

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Catalog No. Product Name Information Product Use Citations Product Validations
S7947 PX-12 PX-12 (DB05448, 1-methyl propyl 2-imidazolyl disulfide) is a potent thioredoxin-1 (Trx-1) inhibitor by irreversibly thioalkylation of Cys73 of Trx-1. Phase 2.
Br J Cancer, 2022, 10.1038/s41416-022-01835-1
Mol Biol Rep, 2022, 10.1007/s11033-022-07177-8
Free Radic Biol Med, 2020, S0891-5849(20)31609-9
S7947 PX-12 PX-12 (DB05448, 1-methyl propyl 2-imidazolyl disulfide) is a potent thioredoxin-1 (Trx-1) inhibitor by irreversibly thioalkylation of Cys73 of Trx-1. Phase 2.
Br J Cancer, 2022, 10.1038/s41416-022-01835-1
Mol Biol Rep, 2022, 10.1007/s11033-022-07177-8
Free Radic Biol Med, 2020, S0891-5849(20)31609-9
Tags: Thioredoxin inhibition | Thioredoxin activation | Thioredoxin activity | Thioredoxin inhibitor review